Xin He
@xinhe2
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Associate Professor of Human Genetics at University of Chicago
Chicago
Joined October 2009
Come join us! UChicago Human Genetics has an open broad computational faculty search (with an emphasis on probabilistic machine learning). First round of application review will begin ~October 15th. https://t.co/MAIb1C7wEe EOE/Vet/Disability.
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Open TT faculty position at the department of medicine at the University of Chicago! Come join us in Genetic Medicine, Biomedical data science, Oncology, or any of the other sections. Apply here:
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There is a position on my new team that just opened! We are looking for a creative and talented data scientist or statistical geneticist to help us use human genetics to drive value in drug development. https://t.co/53mEML1xr2
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Glad to see our paper, with @xinhe2 @mstephens999 @wescrouse Sheng and Kevin, is out today at @NatureGenet! https://t.co/hMfTQYsGuK. We developed a new statistical method, causal-TWAS or cTWAS, to reliably identify causal genes in genome-wide association studies (GWAS). 1/n
nature.com
Nature Genetics - Causal-TWAS (cTWAS) is a statistical framework that adjusts for genetic confounders in transcriptome-wide association studies. Application of cTWAS on common traits leads to...
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Introducing guided sparse factor analysis (GSFA), a statistical framework to detect changes in gene expression resulting from perturbations in single-cell CRISPR screening. @xinhe2 @MengjieChen6 OA paper:
nature.com
Nature Methods - Guided sparse factor analysis (GSFA) is a powerful statistical framework to detect changes in gene expression as a result of perturbations in single-cell CRISPR screening.
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The Department of Human Genetics at University of Chicago is searching for a faculty candidate in Computational genetic and genomics. Please share this job ad with your colleagues:
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My department @UChicagoPHS now has a twitter account. If interested follow us and RT 👇
The Department of Public Health Sciences at the University of Chicago now has a twitter account! Follow @UChicagoPHS for PHS-related accouncements, news, and faculty and student updates.
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The work involved the collaborator @MengjieChen6, and many lab members, including @SimingZhao06.
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We have a very successful collaboration with the lab of Jubao Duan, @jubao9812! We showed that variants disrupting chromatin accessibility in iPSC-derived neurons are highly enriched with risk variants of psychiatric disorders. See:
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Hello Everybody, I am now directing the Bioinformatics Core at U Chicago Biological Science Division. We are now recruiting a PhD level Bioinformatician (well compensated staff scientist). Please share the post. If you're on the market, please check us out.
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Very excited to share our paper, in collaboration with Chuan He's lab at U of Chicago and @mstephens999 :
nature.com
Nature Genetics - Quantitative trait locus (QTL) mapping of N6-methyladenosine (m6A) in human cells highlights the role of RNA-binding proteins, RNA secondary structure and context-dependent m6A...
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University of Chicago department of human genetics statement on police violence, racism and genetics: https://t.co/XysyEsihvF
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My lab is looking for a #postdoc in computational biology/genetics, jointly supervised with Matthew Stephens @mstephens999). See the ad: https://t.co/9ZZUVHCAQf Please RT!
forms.stat.ufl.edu
This is a current listing of job announcements related to Statistics. To submit a job for posting please use the Statistics Job Submission Form. Please note that jobs are posted within 24hrs of...
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Our paper on Mendelian randomization accounting for correlated and uncorrelated horizontal pleiotropy is out! https://t.co/A4FjugZkf0 with @mstephens999 and @xinhe2
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The Stephens lab is looking for postdocs - if you have a PhD in statistics, computational biology, or related discipline, and are interested in methods dev and/or analysis of single cell transcriptomic data please email me at mstephens@uchicago.edu with CV. Please RT!
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Our work with @SimingZhao06 and @mstephens999, on modeling evolution of cancer driver genes is now published:
nature.com
Nature Communications - Finding driver genes sheds lights on the biological mechanisms propelling the development of a tumour, and can suggest therapeutic strategies. Here, the authors develop...
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