
Vince Luca
@vcluca1
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Principal Investigator | Moffitt Cancer Center Department of Immunology | Scientific Director - Center for Antibody & Protein Engineering
Tampa, FL
Joined February 2011
I am excited to share our @NatureComms paper describing the structure of #LAG3 bound to MHC-II. This project was carried out by @SuperMQQ et al at @MoffittResearch and provides new insights into the mechanism by which LAG3 suppresses T cell activation.
nature.com
Nature Communications - Lymphocyte activation gene-3 (LAG3) is an immune checkpoint protein recently approved as a target for anti-melanoma therapy. Here, the authors solve the structure of mouse...
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RT @DrJuanLMendoza: I am happy to share that we have a great opportunity for a postdoctoral scientist. Please share.
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RT @srikosuri: Solving the "replication crisis" is dumb because (1) it's not a crisis, (2) the medicine is worse than the disease. Much of….
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RT @Satpathology: I once quit a study section mid-review because a reviewer gave an exceptionally productive physician-scientist trainee (a….
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I’m not sure where the right place to report this is (@CityofTampa @cot_traffic). The traffic light timing is malfunctioning at the left turn from Fowler to Bruce B Downs. There is a massivebackup and it’s only turning green for ~5 seconds at a time.
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RT @aaronmring: You’ve heard of vibe coding—meet vibe protein design. Click, launch, and watch the binders roll in. That’s what we're unvei….
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RT @CancerBiol_PhD: 🎓 📷 Congratulations to Elliot Medina, PhD @ElliotMedina31 on the successful defense of his doctoral dissertation entitl….
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RT @ProfGregSawyer: At today’s ribbon cutting for the Nikon Center of Excellence, long-time @MoffittNews supporter Mr. Ted Couch shared ins….
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My first PhD student, Elliot Medina, defended his thesis today! And as an added bonus, he got a job offer during his Q&A session! . Elliot is an absolute wizard of a protein engineer. I could not have been more fortunate to have him as employee #1 in my lab @MoffittResearch
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RT @Noahpinion: Trump is trying to root out wokeness in the scientific establishment. But he's smashing American science in the process. h….
noahpinion.blog
An experiment I would prefer not to conduct.
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RT @RepAuchincloss: Basic science is inspired by curiosity, accountable to evidence, and subject to peer review. Politics should have no ro….
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RT @PatrickHwuMD: Honored to join @ibaworldwide leaders and guests today in Paris for a keynote sharing Moffitt’s work, including our #Sper….
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RT @JuddLegum: 1. BREAKING . The Trump administration is maintaining a funding freeze at the National Institutes of Health (NIH) in defian….
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RT @tombrettlab: Really proud of our newest study with @JABLab3 , led by @GrevenJessica with major contributions from @WydraJosh Cynthia Zh….
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Very cool paper from Marta Borowska in the Garcia lab @Stanford_MCP. They drew inspiration from adenoviral immune evasion to engineer CD45-targeting proteins that suppress T cell activation.
New research from @Stanford_MCP describes the structural mechanism that enables #adenoviruses to escape immunity by targeting #CD45 on T cells. Read more in Science #Immunology:
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RT @tombrettlab: We are recruiting for Investigator (Tenure) track faculty @WUSTL in the Dept of Pathology and Immunology; Division of Lab….
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