Uciel
@ucielp
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Group Leader of the Computational RNA Biology Lab
Barcelona, Spain
Joined September 2010
Here we use In-cell NMR to study degradation of misfolded proteins in the periplasm of live bacterial cells 👇👇 A fun project with @TatoVila_1962
@rpierattelli, FJH y LJG! @IBR_CONICET @Plabem1 @cerm_cirmmp @fbioyfunr
https://t.co/Z1pxqwRYGi
nature.com
Nature Communications - In-cell NMR reveals the molecular details of NDM-1 degradation, an enzyme linked to antibiotic resistance, and sheds light on protein quality control in the periplasm of...
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Excited to share our latest advances in RNA structural discovery at Harvard Medical School, with my kids there to share the moment. Huge thanks to Fede and @silvirouskin for the invitation and their expert feedback! it was truly inspiring.
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Among the pioneers in discovering and characterizing light sensing and physiological responses in bacterial chemotrophic pathogens such as Acinetobacter baumannii, we now show that these microorganisms exhibit light-modulated circadian rhythms. https://t.co/fmy87GGke1
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Large language models are reshaping the way we do science, but how well do they actually understand plant molecular biology? ➡️We created MoBiPlant to answer this. 📝Preprint: https://t.co/EhQf4YofLw 💾Dataset: https://t.co/D1B5lBj0UR (Thread below)
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🪴 🤖 New preprint: What do LLMs know about Plant Molecular Biology? Take a look at MoBiPlant, our new benchmark to measure LLMs performance built by more than 100 plant scientist from 19 countries! More info in this thread 👇 https://t.co/DlRYZCX00x
Large language models are reshaping the way we do science, but how well do they actually understand plant molecular biology? ➡️We created MoBiPlant to answer this. 📝Preprint: https://t.co/EhQf4YofLw 💾Dataset: https://t.co/D1B5lBj0UR (Thread below)
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🌱🧬New preprint: What do LLMs know about Plant Molecular Biology? Take a look at MoBiPlant, our new benchmark to measure LLMs performance built by more than 100 plant scientists from 19 countries! Amazing collaboration! 🚀 More info in this thread 👇 https://t.co/xujvRjUFj0
Large language models are reshaping the way we do science, but how well do they actually understand plant molecular biology? ➡️We created MoBiPlant to answer this. 📝Preprint: https://t.co/EhQf4YofLw 💾Dataset: https://t.co/D1B5lBj0UR (Thread below)
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Riboswitches are super cool and the next frontier in RNA therapeutics !
#Guanidine was known since the 1870s to affect muscle function. Vertebrates have guanidine-sensing #riboswitch RNAs linked to genes relevant to muscle disorders, including some for Ca2+ signaling and others relevant to #ataxia symptoms. @NatureComms
https://t.co/TdoTLvIL0t
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Happy to share that our lab got funded through Spain’s PID2024 call!! We'll be exploring how RNA structure, not just sequence, shapes lncRNA function across evolution. Congrats to those selected, and strength to those who weren’t in this highly competitive process.
Publicamos la Propuesta de Resolución Provisional de la convocatoria Proyectos Generación de Conocimiento 2024 (#PID2024). ✅ Dotación histórica de 667M de euros (+ 2% que el año anterior). ✅ Se han presentado 7.190 solicitudes. 🆕 Informe interactivo para buscar ayudas por
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Big congrats @incaRNAtolab on this amazing work just out in Nature Biotechnology! RNA structure ensembles and regulatory switches!
I am so incredibly excited to share our latest work, on the exploration of #RNA secondary structure ensembles and discovery of RNA regulatory structural switches in bacteria and human cells, out today in @NatureBiotech: https://t.co/tqiilEGJkp. A short tread! (1/n)
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#PublicationAlert! Our long-standing collaboration with HKI Jena and colleagues about the role of albumin in virulence of C. Albicans is now published in Nature Communications! See the full paper below https://t.co/951kH70rwG Congrats to all contributors!
nature.com
Nature Communications - Candida albicans normally relies on specific pathogenicity mechanisms to cause tissue damage. This study reveals that when sensing host albumin, C. albicans, even avirulent...
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Calling all #RNA & #AI researchers! 🧬🤖 Submissions are open for the new open‑access collection “Exploring RNA Biology with Deep Learning Algorithms” in RNA Biology that I am guest editing with @YiliangDing 📄⬇️ https://t.co/gQzF5ckD5S
#DeepLearning #bioinformatics #CompBio
michaelwolfinger.com
The RNA biology journal is launching a new open‑access article collection called “Exploring RNA Biology with Deep Learning Algorithms” to bring together the latest breakthroughs at the intersection...
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Now published in ACS Applied Bio Materials. You can read the published version here: https://t.co/f6f6uCo7jA
New preprint: we isolated an heterogeneous population comprising both large and small #ExtracellularVesicles. Using a modified immuno-gold protocol, we show that, at least in U-2 OS EVs, CD9 and CD81 are enriched in EVs < 100 nm. https://t.co/QmRcjaxvGr
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I am excited to share my research is now published! 📚 Genomically-selected antifungal Bacillaceae strains improve wheat yield and baking quality https://t.co/s7rNOa3t80
@SN and #SNAuthor.
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Oportunidad para hacer bioinfo & machine learning ->
linkedin.com
Posted 7:33:00 PM. Job Title: Computational Biologist / AI Scientist Location: Buenos Aires // RemoteJob Type:…See this and similar jobs on LinkedIn.
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The IncaRNAto lab is seeking a motivated #PhD candidate, interested in studying #RNA structural ensemble dynamics in living cells. Here's the link to the vacancy: https://t.co/eaQbAOVBG4. Please share!
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🧬 New Paper Alert! Can RNA structure prediction benefit from large language models? Our study benchmarks 6 state-of-the-art RNA-LLMs across diverse datasets to find out 👉 Our preprint: https://t.co/yxzp4VAf8e 👉 Paper & code: https://t.co/ZEcz4dLQ6H
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🎉 Thrilled to share our latest research published in @PNASNews! 🧬 Our study uncovers how PKA regulatory subunits dynamically relocate during sperm capacitation, linking PKA to the CatSper signaling complex—shedding light on the molecular choreography essential for fertilization
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Check out our latest review in @MolecularCell! We discuss how formaldehyde, a toxic metabolic by-product, threatens genome stability and disrupts cellular homeostasis. 👏Terrific job by the talented #MartaValverde
@CarrerasIJC 📰👉 https://t.co/2YqgFaqYgg
cell.com
Formaldehyde is an endogenous reactive metabolite that challenges cellular integrity. This review outlines its metabolic sources, detoxification pathways, and protective mechanisms, highlighting...
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Happy to be featured in this Technology Feature by Michael Eisenstein in Nature Methods about the present and future of #RNA structure analysis, along with @ywan_wan, @RouskinLab, @JosephYesselman and many other colleagues working in this amazing field! https://t.co/Sv4SVawBnX
nature.com
Nature Methods - A steadily growing toolbox of techniques is helping researchers to understand the structural complexity that enables RNA molecules to perform a dizzying array of functions in the...
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