Tsotne Chitiashvili
@tsotnech
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Scientist at @Calico
San Francisco, CA
Joined May 2008
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š¢ Ready to rethink XIST? Our latest work, now in Cell, challenges two fundamental assumptions about XIST: its cis-limited action, and its role in equalizing gene expression between XX and XY genotypes. Dive in šš¤æ(1/6) .
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Last but not least thanks to @PlathLab and @clarklabucla1 for their help and guidance and many thanks to all the authors contributing to this work! (3/3).
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Here we show (2/3): .- FGFR3 marks human primordial germ cells (hPGCs) in vivo.- Upon advancement to Prophase I or Meiosis I FGFR3 gets down-regulated .- hPGCs can be enriched from prenatal human ovaries using FGFR3 FACS.
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Happy to share our most recent paper (1/3):. FGFR3 is expressed by human primordial germ cells and is repressed after meiotic initiation to form primordial oocytes
cell.com
Stem cell biology benefits from inĀ vivo reference maps of human cell types to enable comparisons with human cells generated inĀ vitro using stem cell differentiation. In this study, Chitiashvili and...
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RT @clarklabucla1: The Clark Lab is HIRING an experienced Staff Research Associate!! Do you want to join a dynamic and supportive team doiā¦.
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Congrats @YolandaMarkaki!.
Excited to share our latest publication out @CellCellPress where we explore how Xist nucleates local protein gradients to propagate gene silencing during X chromosome inactivation. 1/15 ..š§«š§¬š¬š§µ.
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New SARS-CoV-2 variants have changed the pandemic. What will the virus do next?
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RT @IchinoLucia: So happy to share my first paper, published today in Science! š.How does DNA methylation repress gā¦.
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<3.
OurJune issue features several exciting studies on stem cell models of human development, showing hESCs make trophectoderm & can be used to create blastoids. The cover art by Misaki Ouchida plays on the etymology of "placenta" which is ācakeā in Latin.
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Lots of interesting stories in this issue of CSC, but can we appreciate awesome cover art? Kudos to the author!.
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She was probably soooo proud to get the vaccine shot! Amazing story! .
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RT @SFGate: The state of California launched a new program Friday that gives the residents the opportunity to get vaccinated by volunteerinā¦.
sfgate.com
MyTurnVolunteer is an online tool that allows you to look for clinics and mass vaccine...
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RT @demarco_rafa: New review out with @JonesLabUCLA: Redox signaling as a modulator of germline stem cell behavior: Implications for regeneā¦.
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Boris Johnson pipetting is so uncomfortable to watch!.
For reasons the reference laboratory could not readily explain, the antibody titer in every well at every dilution of every patient sample, including positive and negative controls, was a homogeneous 1:1,028.
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RT @MonicaGandhi9: Okay, took me a long time to make this table (icons and everything) so please appreciate column 6. What protects from seā¦.
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