Now out - we show that PV and SOM inhibitory interneurons contribute synergistically to generate cortical oscillations at various frequencies (from gamma down to beta/alpha) and control network stability... https://t.co/5IGtgoZJKK - with Farzin Tahvili and Matteo Di Volo - 1/3

Also check out our website for a detailed guide and overview: https://t.co/I9plsqjfMe

GUI walkthrough & tutorial video here: https://t.co/ik7wdhQJBB Code & install instructions on GitHub:

🚀 🚀Preprint out now on bioRxiv! “KIASORT: Knowledge-Integrated Automated Spike Sorting for Geometry-Free Neuron Tracking” Brings geometry-free, per-neuron drift correction, without uniform movement assumptions in large-scale recordings. 🔗 https://t.co/FDDfOWixvl 👇Code + docs

Notable: mental re-ordering (swapping) was more likely with better learning the initial sequence (=memory) (otherwise NHPs keep using serial chaining strategy) and correlates with working memory performance - kudos to Xuan, Adam and Seema for pulling this off ! 2 / 2

New paper shows how nonhuman primates learn (5-) object sequences and use context cues to mentally re-order objects within a learned sequence – showing that NHPs form non-spatial cognitive maps 1 / 2

Overall, the effects suggests that stimulation induced uncertainty in the ACC (with few exceptions) and in striatum boosted feature-specific credit assignment and updating of attentional priorities. Kudos to Louis, Kia, Charlie, Adam and Paul for pulling this off.

Modeling suggests stimulation improved/impaired directed exploration/information gathering of relevant objects and the updating of feature values. Recordings showed ACC firing tracked feature uncertainty and error history, while striatum tracked stronger feature values of objects

New paper shows causal effects of gaze-contingent stimulation on learning feature-based attention: Treuting et al. (2025) Adaptive Reinforcement Learning is causally supported by Anterior Cingulate Cortex and Striatum. Neuron https://t.co/nEsn6HXW9j 1/2

Experience reorganizes content-specific memory traces in macaques 🐒🧠. @perpl_lab @AymanAljishi https://t.co/TDx7wYbgE0

Humor me: I’m reactivating the latest preprint from the lab (itza “new” trace) 🤓

What makes memories last—dynamic ensembles or static synapses? | The Transmitter: Neuroscience News and… https://t.co/mqcd0KOD5a Thanks to @JasonSynaptic for organizing!

Excited to share that the latest @perpl_lab paper is published in @CellReports. We describe the dynamics of superficial and deep CA1 pyramidal cells and identified putative groups of inhibitory cells in freely moving, thinking, and sleeping macaques. 1/n

Led by Satoka Fujimoto and with @RussBEneuro and @HelenMaybergMD our first paper on the effects of deep brain stimulation in the brain. What’s exciting is that we find it induces white matter remodeling in specific tracts. @SinaiBrain

The conclusion is the ACC causally meta-adjusts learning strategies during periods of uncertainty to infer which objects to choose/attend/explore for best outcomes. kudos to @LTreuting44120 and the team with @KiaBanaie to pull this off!! 3/3

An adaptive RL/WM learning model suggests ACC-stimulation had primary effects: impairing integration of feature specific prediction errors over time; and secondary effects: impairing meta-adjustment of exploration-over-exploitation AND the use of working memory for learning. 2/3

If you are interested in how the Anterior Cingulate Cortex affects behavior: Brief ACC-stimulation when an object is fixated changes inferring the relevance of that object over other objects, i.e. ACC reduces uncertainty about the objects' value. 1/3 https://t.co/mCkkHC3Svg

Group photo of inaugural Multi-Area, high-Density, Laminar Neurophysiology (MaDeLaNe) workshop @VanderbiltU. Thanks @martin_a_vinck @perpl_lab @AkellaShailaja @jake_westerberg @KiaBanaie @thiwomTO Alex Maier, students and tutors! LFPs and spikes making a cameo - see them!?? ;)

Check out our new paper on "state-dependent circuit dynamics of superficial and deep CA1 pyramidal cells in macaques" now available on @biorxivpreprint #biorxiv_neursci @perpl_lab https://t.co/gP2RhBzQnR