Harry Low’s Lab
@thelowlab
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Bacterial pathogenesis. Antibiotic discovery. Membrane remodelling. Structural biology #cryoEM @imperialcollege @lowlab.bsky.social
Imperial College, London
Joined August 2017
Now out in NSMB for those who missed our biorxiv back in 2023..
The missing piece in the bacterial #ESCRT-III story.. #Vipp1 forms dynamic spiral filaments on membrane! Spirals are springs that drive 3D ring formation in the spiral centre! 😎😵💫 Wonderful collaboration with @Colom_D @RouxLab… 1/2 https://t.co/BRJhMGRE8u
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Two weeks left to apply for a PhD with us at MRC-LMB in Cambridge. Join our team for an exciting project on transcription-coupled splicing to understand human gene regulation 🧬 Feel free to get in touch directly #PhD #cryoEM #biochemistry
https://t.co/Ud5RRaw5Px
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Please RT. Post-doc opportunity alert! 💥 closing 10th December.. Come join our team ( https://t.co/Q2PixVbm9k) at Imperial, London, working on the structure and mechanism of bacterial secretion systems. For more details and to apply please see https://t.co/ko2GpcLRkW
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Latest from the lab: we’ve found that arbitrium phages can cross-communicate across species. Their molecular “language” isn’t as private as we thought. The original idea came from @AlbertoMarina14. As always, he was right. https://t.co/57t55dymdV
biorxiv.org
Arbitrium is a communication system that helps bacteriophages decide between lysis and lysogeny via secreted peptides. In arbitrium, the AimP peptide binds its cognate AimR receptor to repress aimX...
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Formal ads are out now for openings in our #CDlab: https://t.co/QETvVUv9p2
https://t.co/E2dt3x660W
https://t.co/AHmdmM9xs8
https://t.co/mcme2468d1
https://t.co/fv9Hn6d6hP So, ambitious talented experimentalists: please apply!
careers.tudelft.nl
Postdoc Researcher for Studying in Vitro Transport Across the Nuclear Pore Complex
WORK! My lab currently have 5 (!) open positions for postdocs/PhD students for: -Nanopore protein sequencing -Archaeal CDV cell division -Microfluidics for synthetic cells -Nuclear Pore Complex -Origami mimics of peroxisomes Please apply! https://t.co/t4Yk0aZLHF RT=👍
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Our collaborative work on the T9SS is just out in Nature Communications! Fantastic work led by Dhana Gorasia and Eric Hanssen. This paper reveals the structure of the T9SS outer membrane PorKN ring complex and mechanistic insights into protein secretion. https://t.co/gvU2kdY4Fs
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Please RT 🙏 If you’re an ECR working in the fields of structural or synthetic biology wishing to start your lab then come join us at Imperial, London. We’re looking to support outstanding individuals for external Career Development Awards/Fellowships https://t.co/Mw7aNCZle5
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We're hiring for a Head of Department to lead one of Europe’s largest and most impactful centres for infectious disease research — right here at @imperialcollege. We're looking for a strategic leader with vision and drive. Apply by 15 September👇 https://t.co/qTuQwPuTNy
imperial.ac.uk
Please note that job descriptions are not exhaustive, and you may be asked to take on additional duties that align with the key responsibilities ment...
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❗️ Exciting review alert❗️focussing on the evolution and mechanism of prokaryotic ESCRT-III-like systems.. fun collaboration with Tom Williams! https://t.co/Gpp9IEBa9H
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We are looking for an Assistant Professor / Lecturer in Molecular Microbiology @ImperialInfect @CBRB_Imperial. All areas of bacterial/fungal infection biology considered. Details👇. Please contact me by email for any further information.
imperial.ac.uk
Please note that job descriptions are not exhaustive, and you may be asked to take on additional duties that align with the key responsibilities ment...
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The Beeby lab's magnum opus on the Campylobacter flagellum is out. This is a uniquely powerful flagellum and how it evolved out of simpler precursors will keep us busy for a while still. Check it out!
nature.com
Nature Microbiology - In situ cryoEM and modelling of the Campylobacter jejuni flagellar motor characterize the periplasmic scaffold and the structural basis for increased torque generation.
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Brilliant🔥
Exciting findings from @JunLiuLab #postdoc @YueJianUSTC @YaleMed Architecture and activation of the Legionella Dot/Icm type IVB secretion machine #cryoEM #cryoET #Legionella
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Looking for a fully-funded D. Phil. / Ph.D. studentship in structural biology and vaccinology? Come to join our team. Fully and generously funded by a donation from the Kyner-Field family with full fees at overseas level. Join us?? https://t.co/KZMGLmTGI3
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We have a funded #PhD project working on RSV, antibodies and computational biology. Deadline 30th June https://t.co/ou8v8Hs4cc
imperial.ac.uk
The MRC funded projects for the current call are listed below. The application form will ask for one project to be selected or two projects to b...
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We describe why Hfq forms condensates in nitrogen starved E.coli by @JoshMcquail and colleagues:
biorxiv.org
Ribonucleoprotein-condensates are membraneless compartments that concentrate RNA-binding proteins and RNA and play key roles in cellular adaptation across both eukaryotes and bacteria. While the...
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Postdoc position available! This is a 2-year post funded by the Academy of Medical Sciences. You'll be based in the Centre for Bacterial Cell Biology here in Newcastle, using super-resolution microscopy to look at the bacterial cell wall. 🔬🦠 RT 🙏 https://t.co/qFgp19Vz5Y
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Please RT. Post-doc opportunity alert! 💥 closing 5th May.. Come join our team ( https://t.co/7PN1tJGp4H) at Imperial, London, working on bacterial secretion systems. The position is funded by the Wellcome Trust. For more details and to apply please see https://t.co/MSEJe6UWMW
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Recently out! An awesome commentary on our bacterial ESCRT-III work https://t.co/eUvfQT9jCu - big thanks to John McCullough and Wes Sundquist for this. And of course big shout out to #NSMB for the tasty cover!
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More awesome cryo-ET from the Liu lab unravelling flagella motor architecture..
MotE-like proteins, including FlgY in Campylobacterota and FlbB in Spirochaetota, form characteristic ring structures across bacterial phyla. https://t.co/LPeHscQyuZ
https://t.co/zNtUe9nHAd
https://t.co/5ZHNtBrydh
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This is jaw dropping level stuff!
Excited to share our pre-print on the molecular architecture of heterochromatin in human cells🧬🔬 w/ @jpkreysing, Johannes Betz,Turoňová lab, @MarinaLusic, Hummer lab, @Beck_Laboratory, @MPIbp 🔗 Preprint here: https://t.co/0tTxZcu0Vz
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Apply by 18 May 2025!
mankalab.org
We are offering a PhD project focused on engineering fluorescently tagged prions in human cells
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