Edward N Smith
@tednsmith
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Biochemist using flux analysis to investigate the amazing metabolism of plants! @HeinemannLab @univgroningen @leesweetlove @oxfordplants.🌱🌿🌵👨🔬
Oxford, England
Joined May 2018
RT @qpb_journal: Our most downloaded article in Quantitative Plant Biology is now available! This groundbreaking piece of research has capt….
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RT @qpb_journal: Join us TOMORROW!. "The Arabidopsis leaf quantitative atlas: A cellular and subcellular mapping through unified data integ….
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RT @emily_flashman: UK plant science twitter, can you help? Is anyone growing whole cell Arabidopsis thaliana cultures and would be happy t….
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Dear @pcanfin @cesarluena @jessicapolfjard @clergeau @jhuitema @MartinHaeusling @AMALRICCatheri1 @MChahim @woelken @PoselBalt @engerer @delarabur @CorinaCretuEU @NicosPapandreou @PetarVitanovMEP @sandor_ronai please read our open letter 📷and vote in favour of NGTs tomorrow!.
37 Nobel Laureates & nearly 1,500 Scientists call on MEPs to support New Genomic Techniques (#NGTs). NGTs give farmers access to new drought-tolerant & nitrogen-efficient crops, helping to produce food more at lower environmental cost.
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RT @weplanetint: 🧬Urgent Appeal for Support on New Genomic Techniques (NGTs) in Europe 🌍🔬. 🚨 An urgent call to action! Our open letter, end….
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We can grow more food with fewer resources if we improve the efficiency of photosynthesis. Our new review explores how to do this by taking advantage of existing natural variation and bypassing inefficient pathways with completely new ones! @gain4crops.
.@gain4crops crew review on: Improving photosynthetic efficiency toward food security: Strategies, advances, and perspectives: Molecular Plant
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A new open-source python package for isotopically nonstationary MFA. Looks promising - anyone tested this out yet?
pubs.acs.org
13C metabolic flux analysis is a powerful tool for metabolism characterization in metabolic engineering and synthetic biology. However, the widespread adoption of this tool is hindered by limited...
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RT @schwarzland_lab: 🌟 Exciting opportunities @WWU_Muenster within DFG Research Unit #GoPMF! Join us as. 1. Postdoc.2. Part-time Technician….
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Super exciting to escape my computer models and see where our metabolic predictions will be tested in an actual field of sunflowers! 🌻Thanks to everyone @gain4crops and @agroscope for hosting!
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Congratulations Sanu! - looking forward to seeing all the exciting science you get up to here!.
We welcome Dr. Sanu Shameer as the newest faculty member. @SanuShameer did his Ph.D. with @MetExplore at INRA Toulouse & postdoctoral fellowship with @leesweetlove at the @OxfordBiology. His research focuses on using mathematical models to study metabolism in biological systems.
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RT @ADHansonLab: ICYMI - News you can use for #SyntheticBiology researchers w/ plant interests: @PlantPhys welcomes plant-related #SynBio s….
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I love how my favourite metabolite, NAD(P)H, pops up everywhere - this time showing how metabolism oscillates during the cell cycle. It was fun to work on this project and see how computational modelling is so useful for interpreting complex processes!.
I am more than happy to be able to share this study that has been my passion for many years. I was lucky that I got to work on this extremely interesting and fundamental topic. A long thread will follow soon. @HeinemannLab @ResearchGbb @univgroningen
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RT @ZantenMartijn: Virus discovered in world’s most widely used research plant
uu.nl
The presence of the virus in thale cress, the most widely studied plant species, potentially has far-reaching implications for research projects.
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An excellent review of metabolic engineering principles in microbes. These concepts are also applicable to engineering plants which is exactly what we're attempting in the @gain4crops consortium! 🌻🔀.
Have you ever been stuck in your #pathway design by a #bottleneck and not found your way #around it yet? Then, this fresh review on the topic of #bypasses ↪️written together w/ @NicoC_MicSynBio, @PabloINik, @SteffenNLindner might help 🧵(1/7).
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RT @schwarzland_lab: PhD position in the fantastic lab of @SonnewaldUwe, to explore organelle positioning as a principle of metabolic regul….
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The Codon newsletter from @NikoMcCarty is my go to source for keeping up with biotech and synbio research. This week it features a great summary of recent efforts to improve photosynthesis 🌻
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Changing redox energy balance between chloroplasts and mitochondria might be a way to increase photosynthetic efficiency and crop yields. Great use of fluorescent biosensors to show the effects of modifying malate shuttling on NADH levels👇Congrats @BeaMorenoGarcia!.
What happens if you perturb the shuttling of NAD(P)H💥 and ATP⚡️ between plant organelles? We targeted connection points chloroplast-cytosol-mitochondria and found changes to the NADH/NAD+ ratios in the dark in tobacco leaves🌱. Out today @JPlantPhysiol!.
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RT @SanuShameer: FBA and ODE models have their own strengths and weaknesses. Here we present a hybrid ODE-FBA model of leaf metabolism that….
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