Takatsugu Miyazaki
@taka_enzyme
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Enzymology / Structural Biology / CAZymes / Associate Professor at Shizuoka University, Japan. ただのCAZyオタク (CAZy nerd). ex-swimmer
Joined July 2020
日本応用糖質科学会(監修)『澱粉の事典』 本書では澱粉の基礎科学から利用加工まで，各1～4頁の読み切り形式で解説。 A5判600ページ 定価17,600円（本体16,000円＋税） https://t.co/du2pr3SEMp
asakura.co.jp
澱粉は光合成により植物内部で作られる炭水化物（糖質）の一種であり，私たちのエネルギー源としてはもちろん，工業製品としても重要である。本書では澱粉の基礎科学から利用加工まで，各1～4頁の読み切り形式で解説。〔内容〕澱粉の基礎科学／澱粉関連酵素／澱粉・糖質の製造・特性／澱粉・糖質の産業利用／澱粉・糖質の調理科学
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We’re excited to share that our paper on the crystal structure of dextran dextrinase is now published open access in JBC! https://t.co/pV4bz1VzGs
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The structure investigation of GH174 endo-1,3-fucanase revealed an unusual glycoside hydrolase fold #CAZyme #GlycosideHydrolase #GH174
https://t.co/0bTFo5bInw
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A new CBM family, CBM104! A cellulose-binding domain specific for native crystalline cellulose in lytic polysaccharide monooxygenase from the brown-rot fungus Gloeophyllum trabeum #CAZyme #CarbohydrateBindingModule #CBM104
https://t.co/FPppsU3e2q
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SusC/D-like proteins in Gammaproteobacteria that utilize fructans #CAZyme #GlycosideHydrolase #GH32 #GH68 #PolysaccharideUtilizationLocus #PUL
https://t.co/pDuhszyNml
biorxiv.org
SusC/D-like proteins are essential components of glycan utilization machineries in Bacteroidota , but remain unknown in other bacterial phyla. The glycan-binding SusD-like protein forms a ‘lid’ on...
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We are proud to share a curated collection of cutting-edge research articles in the JBC, spotlighting pioneering discoveries and advancements in glycobiology. https://t.co/dWSlmWF9ES
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Prevotella are major contributors of sialidases in the human vaginal microbiome | PNAS #CAZyme #GlycosideHydrolase #GH33
https://t.co/35fdx7tGyG
pnas.org
Elevated bacterial sialidase activity in the female genital tract is strongly associated with poor health outcomes including preterm birth and bact...
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Cobalt as a Cofactor for α-Galactosaminidase-Catalyzed Cleavage of Blood Group Antigens #CAZyme #GlycosideHydrolase #GH36
https://t.co/XuyTadWmYb
pubs.acs.org
Enzymatic cleavage of the terminal α-N-acetylgalactosamine of the A-antigen of red blood cells by gut commensal organisms such as Flavonifractor plautii is achieved in a two-step process in which a...
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The molecular basis of cereal mixed-linkage β-glucan utilization by the human gut bacterium Segatella copri #CAZyme #GlycosideHydrolase #GH5_4 #GH3 #PolysaccharideUtilizationLocus #PUL
https://t.co/NS3ghWl3IJ
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Functional role of carbohydrate-binding modules in multi-modular chitinase OfChtII #CAZyme #CarbohydrateBindingModule #CBM14 #GlycosideHydrolase #GH18
https://t.co/WUgj8fGdJa
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Happy to see our Trichuris hexosaminidase paper out in Biochemistry. A particular thanks to Annabelle Varrot @Cermav_UPR5301 for supervising Zuzanna (our former @BioToP_PhD student) - otherwise there would be no crystal structure of HEX-2! #glycotime
https://t.co/tGC7xUIjPD
pubs.acs.org
Hexosaminidases are key enzymes in glycoconjugate metabolism and occur in all kingdoms of life. Here, we have investigated the phylogeny of the GH20 glycosyl hydrolase family in nematodes and...
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Broad Protection against Invasive Fungal Disease from a Nanobody @RamonHu08403543 @unizar @bifi_unizar @cphglyco @ARAID_ES @EvaGalvezB, @PardoGalvez_Lab @ICB_CSIC @SaludGlobalCSIC @IISAragon @ciberinfec #AngewandteVIP #AngewandteVIP
onlinelibrary.wiley.com
Nanobodies show promise in treating invasive fungal diseases such as aspergillosis and cryptococcosis. By selectively targeting enzymes critical for fungal cell wall remodeling, these single-domain...
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Polyelectrolyte mannan from diatoms reshapes sunlit ocean microbiome https://t.co/onZXing15h
#bioRxiv
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静岡大学農学部では、「生命現象」を軸に、生物学、化学、物理学、地学を基礎とした科学技術の教育研究を行っています。私たちの活動領域は植物科学、バイオテクノロジー、環境科学、食品栄養化学、材料工学、生物化学、土壌学、微生物学、経済学など、基礎から応用にわたる幅広い分野に及びます。
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早期公開 Crystal Structure of Bifidobacterium bifidum Glycoside Hydrolase Family 110 α-Galactosidase Specific for Blood Group B Antigen Kashima et al., J. Appl. Glycosci. https://t.co/aCNFd2rFT3
jstage.jst.go.jp
To overcome incompatibility issues and increase the possibility of blood transfusion, technologies that enable efficient conversion of A- and B-type r …
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Anthocyanin glucosylation mediated by a glycoside hydrolase family 3 protein in purple carrot #CAZyme #GlycosideHydrolase #GH3
https://t.co/6Zzy7YSM4S
onlinelibrary.wiley.com
Glucosylation of the purple carrot anthocyanin cyanidin 3-O-(2″-O-xylosyl)-(6″-O-sinapoylglucosyl)-galactoside is mediated by a glycoside hydrolase family 3 vacuolar enzyme that catalyzes a reaction...
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Our new paper is now online at JACS (@J_A_C_S ). An unprecedented anomer-inverting transglycosylase was found as a phytopathogenic glycan synthase. #glycotime, #CAZyme, #GH186
https://t.co/vxc79eVfSC
pubs.acs.org
Various Xanthomonas species cause well-known plant diseases. Among various pathogenic factors, the role of α-1,6-cyclized β-1,2-glucohexadecaose (CβG16α) produced by Xanthomonas campestris pv....
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Exploring the sequence-function space of microbial fucosidases #CAZyme #GlycosideHydrolase #GH29
https://t.co/n79cPfDiBf
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Our new publication about GH13_30 alpha-glucosidase. A part of special issue "Enzymatic synthesis, modification, and structure-functionality analysis of starch and starch derivatives" edited by Birte Svensson, Stefan Janecek, and Yuxiang Bai. https://t.co/K1fc7PhwV3
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