
Takatsugu Miyazaki
@taka_enzyme
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Enzymology / Structural Biology / CAZymes / Associate Professor at Shizuoka University, Japan. ただのCAZyオタク (CAZy nerd). ex-swimmer
Joined July 2020
RT @kiku_dake: We’re excited to share that our paper on the crystal structure of dextran dextrinase is now published open access in JBC!.ht….
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The structure investigation of GH174 endo-1,3-fucanase revealed an unusual glycoside hydrolase fold.#CAZyme #GlycosideHydrolase #GH174.
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A new CBM family, CBM104!. A cellulose-binding domain specific for native crystalline cellulose in lytic polysaccharide monooxygenase from the brown-rot fungus Gloeophyllum trabeum .#CAZyme #CarbohydrateBindingModule #CBM104.
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SusC/D-like proteins in Gammaproteobacteria that utilize fructans.#CAZyme #GlycosideHydrolase #GH32 #GH68 #PolysaccharideUtilizationLocus #PUL.
biorxiv.org
SusC/D-like proteins are essential components of glycan utilization machineries in Bacteroidota , but remain unknown in other bacterial phyla. The glycan-binding SusD-like protein forms a ‘lid’ on...
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RT @jbiolchem: We are proud to share a curated collection of cutting-edge research articles in the JBC, spotlighting pioneering discoveries….
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Prevotella are major contributors of sialidases in the human vaginal microbiome | PNAS .#CAZyme #GlycosideHydrolase #GH33.
pnas.org
Elevated bacterial sialidase activity in the female genital tract is strongly associated with poor health outcomes including preterm birth and bact...
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Cobalt as a Cofactor for α-Galactosaminidase-Catalyzed Cleavage of Blood Group Antigens.#CAZyme #GlycosideHydrolase #GH36.
pubs.acs.org
Enzymatic cleavage of the terminal α-N-acetylgalactosamine of the A-antigen of red blood cells by gut commensal organisms such as Flavonifractor plautii is achieved in a two-step process in which a...
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The molecular basis of cereal mixed-linkage β-glucan utilization by the human gut bacterium Segatella copri #CAZyme #GlycosideHydrolase #GH5_4 #GH3 #PolysaccharideUtilizationLocus #PUL.
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Functional role of carbohydrate-binding modules in multi-modular chitinase OfChtII.#CAZyme #CarbohydrateBindingModule #CBM14 #GlycosideHydrolase #GH18.
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RT @IainWil92988866: Happy to see our Trichuris hexosaminidase paper out in Biochemistry. A particular thanks to Annabelle Varrot @Cermav_U….
pubs.acs.org
Hexosaminidases are key enzymes in glycoconjugate metabolism and occur in all kingdoms of life. Here, we have investigated the phylogeny of the GH20 glycosyl hydrolase family in nematodes and...
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RT @angew_chem: Broad Protection against Invasive Fungal Disease from a Nanobody @RamonHu08403543 @unizar @bifi_unizar @cphglyco @ARAID_ES….
onlinelibrary.wiley.com
Nanobodies show promise in treating invasive fungal diseases such as aspergillosis and cryptococcosis. By selectively targeting enzymes critical for fungal cell wall remodeling, these single-domain...
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RT @biorxivpreprint: Polyelectrolyte mannan from diatoms reshapes sunlit ocean microbiome #bioRxiv.
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RT @shizu_uni_agr: 静岡大学農学部では、「生命現象」を軸に、生物学、化学、物理学、地学を基礎とした科学技術の教育研究を行っています。私たちの活動領域は植物科学、バイオテクノロジー、環境科学、食品栄養化学、材料工学、生物化学、土壌学、微生物学、経済学など、基礎か….
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RT @sugargroove: 早期公開.Crystal Structure of Bifidobacterium bifidum Glycoside Hydrolase Family 110 α-Galactosidase Specific for Blood Group….
jstage.jst.go.jp
To overcome incompatibility issues and increase the possibility of blood transfusion, technologies that enable efficient conversion of A- and B-type r …
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Anthocyanin glucosylation mediated by a glycoside hydrolase family 3 protein in purple carrot.#CAZyme #GlycosideHydrolase #GH3.
onlinelibrary.wiley.com
Glucosylation of the purple carrot anthocyanin cyanidin 3-O-(2″-O-xylosyl)-(6″-O-sinapoylglucosyl)-galactoside is mediated by a glycoside hydrolase family 3 vacuolar enzyme that catalyzes a reaction...
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RT @periplasmic_gly: Our new paper is now online at JACS (@J_A_C_S ). An unprecedented anomer-inverting transglycosylase was found as a ph….
pubs.acs.org
Various Xanthomonas species cause well-known plant diseases. Among various pathogenic factors, the role of α-1,6-cyclized β-1,2-glucohexadecaose (CβG16α) produced by Xanthomonas campestris pv....
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RT @saburiwtr: Our new publication about GH13_30 alpha-glucosidase. A part of special issue "Enzymatic synthesis, modification, and structu….
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Discovery of a class of glycosaminoglycan lyases with ultrabroad substrate spectrum and their substrate structure preferences.#CAZyme #PolysaccharideLyase #PL35.
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