Stephen Muench
@stemuench
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Leeds, England
Joined October 2017
PhD studentship available! @AstburyCentre @UoL_LICAMM Cardiac muscle function in health and disease CryoEM & MD with @stemuench & Sarah Harris Apply by 6th Jan
findaphd.com
PhD Project - Unravelling the mechanisms of cardiac myosin function in health and disease through molecular dynamic simulation and electron microscopy at University of Leeds, listed on FindAPhD.com
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I have a 4 year fully funded PhD position in collaboration with Prof Helen Walden (Glasgow) and Dr Panos Kotsantis. If you are interested in cell cycle regulation and ubiquitin signalling, this could be for you. https://t.co/f94KMs7KYy
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Very excited to announce that my first PhD project advert is live on @FindAPhD. Led by @KitchenPhil, I'm co-supervising along with @StephenCLH. Please get in touch if you like lipids, membrane proteins and biophysics.
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Great to see one of the past members of our group starting his own lab @AstonAIME . We wish Ben Lane @95bjl the best in his new scientific adventure!
Introducing Dr Benjamin Lane (@95bjl), a new Research Fellow in #AIME. Ben is interested in using structural biology approaches to understand the mechanisms of important bacterial transport proteins, with the aim of identifying new ways of targeting bacteria.
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Very happy to share our latest preprint: Non-covalent spin labelling of TRPC5 ion channels enables EPR studies of protein-ligand interactions | ChemRxiv - https://t.co/MY9Cp3Qqfx
@UoL_LICAMM @AstburyCentre @chemleedsuni @OfficialUoM @univofstandrews @unibirmingham
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We're recruiting! Looking for a postdoc in a fun and inclusive lab doing cutting edge #CryoEM in a great city? Come join us @imperialcollege and be part of an interdisciplinary team funded by @wellcometrust @ImperialLifeSci
https://t.co/dppEZ6QqI8
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Just posted the most biologically important photopharmacology story we've had in the last few years. Ditched the photoswitch design principles we used for the last 10 years, & started all over again. And now it will work in vivo. https://t.co/JTyPfgg3kn 🧵1/n🧵
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Congratulations @isohirst @Astbury_BSL on a clear and engaging review of current #cryoem sample prep! https://t.co/9SMtyb6V8u
portlandpress.com
Sample preparation can present a significant hurdle within single particle cryo-electron microscopy (cryoEM), resulting in issues with reproducibility, data quality or an inability to visualise the...
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Fully-funded EPSRC PhD opportunity @UoL_LICAMM @AstburyCentre developing live-cell chemical cross linking methods to study myosin folding and disease with myself and @MWrightLab
https://t.co/IdpFD366DB apply by 9th August
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Funding (UK fees only!) is in place and the advert will appear ASAP. I am happy to answer questions from eligible candidates. @UoL_LICAMM @IonChannelLeeds @Astbury_BSL Please RT
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Our lab is running the @CR_UK @raceforlife to raise funds and awareness for #breastcancer. 1 in 2 people will get cancer in their lifetime. Thanks to life-saving research I am here to tell my story. Sponsor us through this link. @ImperialSci @CRUKEventsLDN
fundraise.cancerresearchuk.org
1 in 2 people will be diagnosed with cancer in their lifetime. As a scientist working in cancer research, I know the magnitude of this issue, but one year ago I never thought that it would be me....
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Our freshly-accepted paper with @Beth_aimee_cole @KalliGroup @stemuench and @AutifonyLtd. Thanks to the reviewers. #ionchannels A molecular switch in RCK2 triggers sodium-dependent activation of KNa1.1 (KCNT1) potassium channels: Biophysical Journal
cell.com
The Na+-activated K+ channel KNa1.1, encoded by the KCNT1 gene, is an important regulator of neuronal excitability. How intracellular Na+ ions bind and increase channel activity is not well underst...
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Last chance to submit your abstract for the Astbury Conversation! Deadline 4th March. This conference is themed "illuminating life" and we have a super line-up of speakers spanning biophysics, cellular, structural and chemical biology @AstburyCentre
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1/12 - ESIBD+cryoEM paper Now in @ScienceAdvances: Cryo-EM of soft-landed β-galactosidase: Gas-phase and native structures are remarkably similar. collaboration of @ESIBDLab, @KavliOxford, @thermofisher, @TBharat_lab, @UniKonstanz
https://t.co/XSA1vZlyrM
#cryoEM #MassSpec
science.org
Electrospray ion-beam deposition on cold grids and in-vacuum ice growth enable cryo-EM of mass-selected proteins at 2.6 Ã….
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1/6: #CryoEM Exhausted with fighting the air-water interface (AWI) problem during sample grid plunge freezing? We may have an easy solution for you! Read our latest preprint on how we use LEA proteins as AWI sample protectants for challenging samples:
biorxiv.org
Sample loss due to air-water interface (AWI) interactions is a significant challenge during cryo-electron microscopy (cryo-EM) sample grid plunge freezing. We report that small Late Embryogenesis...
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Great PhD programme! Apply by 3rd Jan. Biological mechanisms, population science, AI in healthcare, chemistry, maths, physics - interdisciplinary science at its best - working towards improving care for patients https://t.co/hpTge1TY3S
medicinehealth.leeds.ac.uk
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This one has been a long time in the making… I’m really proud of a stunning paper (IMO!) but much more proud of a stunning team who made it possible @milkowilko @AstburyCentre @Astbury_BSL @RadfordLab @CellPressNews
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I am really excited to announce an EPSRC funded PhD opportunity in my lab to work with me on time-resolved methods development. Please share with your contacts! Open to UK and International students.
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