Jon Lippiat
@DrJonLippiat
Followers
478
Following
372
Media
25
Statuses
483
Ion channel pharmacologist, amongst many other things. Still here, but also @drjonlippiat.bsky.social
Leeds, England
Joined November 2014
I am looking for a post doc with structural biology and/protein science background - if you meet the criteria and feel interested, then feel free to drop an application: https://t.co/sUtxufn1Mg
0
14
23
Here, Emily explains how we go about initiating drug discovery projects for rare and neglected diseases. #ionchannels @ScienceLeeds
The recording from my EpIC seminar earlier this month is up! Have a watch if you'd like to learn about our work identifying novel inhibitors of the KNa1.1 potassium ion channel - my mum watched the first 5 minutes and said that bit was pretty good. https://t.co/cIZfGalARj
0
1
6
Happy to share our latest work in Science Signalling highlighting the essential role of ion channels in KSHV replication. It highlights Kv1.3 as a potential druggable host factor for this oncogenic virus. @scisignal @ScienceLeeds
https://t.co/TUQKwAZ1CY
science.org
Kv1.3 is a potential druggable host factor for inhibiting the lytic replication of an oncogenic herpesvirus.
1
11
28
PhD position available in @LabWykes ! Fantastic news. @EpilepsyInst North West Epilepsy Doctoral Training program lead by @rebbromley @OfficialUoM and @BrainImagingLiv @LivUni. 7 PhDs available to study the impact of anti-seizure drugs on cognition. @mern_UoM @GJBrainResearch
2
18
25
The 39th Cell Physiology Workshop is happening! Applications are now open! To get the application form, please use the QR code, this link ( https://t.co/zsttuc2FAv) or email cpw@liverpool.ac.uk @CPW_Liverpool #CPW2024 #CPW_Liverpool
0
14
16
Our freshly-accepted paper with @Beth_aimee_cole @KalliGroup @stemuench and @AutifonyLtd. Thanks to the reviewers. #ionchannels A molecular switch in RCK2 triggers sodium-dependent activation of KNa1.1 (KCNT1) potassium channels: Biophysical Journal
cell.com
The Na+-activated K+ channel KNa1.1, encoded by the KCNT1 gene, is an important regulator of neuronal excitability. How intracellular Na+ ions bind and increase channel activity is not well underst...
1
3
13
Two exciting Assistant/Associate Professor opportunities @UnivCamPharm: Post 1 - Ageing/Neurodegeneration https://t.co/9sUum7bpKr Post 2 - Structural & Molecular Pharmacology https://t.co/CfvUlnDdja It’s a great place to work, please reach out if you’re interested!
0
24
25
Expressions of interest for PhD opportunity due by 7th January. #ionchannels #PhDOpp
findaphd.com
PhD Project - White Rose BBSRC DTP: The structural and mechanistic basis of neuronal sodium-activated potassium channel function and pharmacology. at University of Leeds, listed on FindAPhD.com
0
2
4
We are recruiting! Lecturer in Neuroscience: Interested in working with other enthusiastic neuroscientists @NeuroLeeds . Check out the link: https://t.co/zjAVyMmCb7 Application deadline: 17th Nov 2023
jobs.leeds.ac.uk
1
16
13
Size matters. There's a very important amino acid in the intracellular domains of KNa1.1 (KCNT1) channels that controls sodium-activation. If it's changed to a smaller one, the channel flips into the sodium-activated state, but any larger it's locked inactive. #ionchannels
A molecular switch in RCK2 triggers sodium-dependent activation of KNa1.1 (KCNT1) potassium channels. https://t.co/TlKC646afl
#biorxiv_biophys
2
8
28
Please apply for the RA position in my group at the UCL GOS ICH! This is funded by an ER UK Endeavour project award and is an exciting project working with patient-derived neurons in epilepsy! https://t.co/DgHHNQc81F contact me for any more info!
ucl.ac.uk
UCL is consistently ranked as one of the top ten universities in the world (QS World University Rankings 2010-2022) and is No.2 in the UK for research power (Research Excellence Framework 2021).
1
34
40
Modelling human KCNT1-epilepsy in Drosophila: a seizure phenotype and drug responses https://t.co/cu7dgBcPnj
#bioRxiv
0
1
0
Faculty position available in the Integrative Membrane Biology team in our department at the University of Leeds. Would suit an ion channel (or transporter/receptor) enthusiast with research in the context of neurological conditions. https://t.co/fSiHFN5TzL
jobs.leeds.ac.uk
0
11
13
Postdoctoral research position available in ion channel research, conducting MD simulations and electrophysiology on KNa1.1 (Slack, KCNT1) potassium channels. Joint project with @antreaskalli and @stemuench
https://t.co/goHN9Mz4fj
#ionchannels
jobs.leeds.ac.uk
0
12
14
An impromptu weekend away to a castle and spa in the middle of the countryside.
0
0
3
PhD opportunity available in my lab starting October 2023 to design, make and test ion channel inhibitors as potential treatments for Epilepsy. A fantastic interdisciplinary project with @DrJonLippiat @MartinMcPhillie @stemuench Email me for more info: https://t.co/RhWPXoNUtW
findaphd.com
PhD Project - Synthesis and biological evaluation of novel potassium channel inhibitors for the development of treatments for KCNT1-related epilepsy at University of Leeds, listed on FindAPhD.com
0
8
7
The Miller lab @UnivCamPharm is looking for an enthusiastic postdoc to study antibody modulation of ion channels! A previous relevant publication from our group is https://t.co/XTBPsCJrWh Job details 👉 https://t.co/cV4aojH2dK DEADLINE 30th NOVEMBER
nature.com
Nature - Cryo-electron microscopy structures are used to identify mechanisms underlying distinct features of extrasynaptic type A γ-aminobutyric acid receptors.
0
4
4