Siekhaus lab
@siekhauslab
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studying migratory steps relevant for metastasis & inflammation with Drosophila macrophages and more #genetics #Drosophila #cancer #immunity #development
Los Angeles, USA
Joined July 2015
Our recent review summarizing findings on macrophage tissue infiltration in Drosophila (developmental, neuroinflammatory, adipose tissue infiltration, tumor ingression and vascular crossing) and how these relate to vertebrate findings. https://t.co/4haPbQrb8M
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Nominate your European Drosophila PhD student for the best thesis prize, sponsored by the European Drosophila Society. More info at: https://t.co/bKSJUNyWtl Submit by Feb 28th to edsprize@gmail.com.
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Los Angeles fires meant Daria and the undergrads evacuated from UCLA to Bay Area, so we had a get together in Daria's fathers house
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I am very excited to share our most recent work on how ‘Cell heterogeneity and fate bistability drive tissue patterning during intestinal regeneration’ ☺️ Thanks a lot to @Silvia_Bar01 @d_brueckner @prisca @EdouardHannezo and all the co-authors!
A perfect start in the new year! 🌱 Regenerating tissues are just an amazing spatio temporal controlled process! Our new manuscript explores how cell heterogeneity and bistability orchestrate intestinal regeneration 🧵 https://t.co/TZaK4D2isb
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The European Drosophila Society @Fly_EDS has just launched a #prize to the best #PhD thesis using #Drosophila. 🏆🪰 Deadline is Feb 2025. Prize = €1000 & keynote presentation at the EDRC in Alicante @edrc2025! More info here:
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Winter sunsets are the best. Did I mention that the @Neuro_CF PhD program just opened for applications and that the lab has an open postdoc position in metabolism?
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Come to sunny San Diego in March to learn the latest about work in the fly and tell everyone about your great results. Abstract submission deadline this Thursday! https://t.co/zrLibFe92V
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If you have different chirality you will not be degraded, good for you! but how can you be synthesized?? Shubham answers your question:
Now published, @SHUBHAM30642626 identifies PLD3/4 as synthesizing BMP, a lipid crucial for #lysosome #lipid #metabolism and #brain health https://t.co/bvyZ1L1G3T
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preach!!! worms are badass, says gary ruvkun. (almost as much as flies). 🪰🪱 https://t.co/g8ABsnw1Os
nytimes.com
A staple in laboratories worldwide, C. elegans is “an experimental dream,” said one scientist.
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Our body🧍♂️🧍♀️ is 60% water 🌊and we often forget that a big chunk of this water is OUTSIDE of cells... Check out our review on how extracellular water sculpt our body during development Discover the beautiful drawings from @louise_dgh and the connections with Bruce Lee's teachings
‘Be water my friend’ Intercellular fluid dynamics in tissue morphogenesis @CurrentBiology with @maitrejl and @Descroix16, we are happy to present you our new review: https://t.co/SqdqxVV2Sw
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🚨 We're Hiring! 🚨 At EMBL Barcelona we build tissues to understand them, and we are looking for a Group Leader in Tissue Biology & Disease Modelling! 🔬 Lead independent research on 3D tissue dynamics & engineering 📅 Apply by 24 Nov 2024 More info: https://t.co/TgBpnWWtJN
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What I love about EMBL Barcelona is the big open lab space that connects all 7 groups and the supportive atmostphere. Even if you're an introvert like me, you'll still end up naturally interacting with other groups and feeling part of a big friendly group. So go ahead and apply!
🚨 We're Hiring! 🚨 At EMBL Barcelona we build tissues to understand them, and we are looking for a Group Leader in Tissue Biology & Disease Modelling! 🔬 Lead independent research on 3D tissue dynamics & engineering 📅 Apply by 24 Nov 2024 More info: https://t.co/TgBpnWWtJN
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My department at K-State is hiring a tenure-track Assistant Professor in Integrative Molecular, Cell, or Developmental Biology! Manhattan, KS is a great college town. Please share widely with your network. I'm happy to answer questions.
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Insects build specialised muscles in one animal? Flight muscle sarcomeres oscillating at 200Hz with gigantic A-bands vs regular larval sarcomeres. How? Solution: 1. I-band titin isoforms 2. Mechanical feedback from I- to A-band. Took 10 years to figure out https://t.co/n5Vz4zH4r8
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Our latest out today @Nature! We revisit a century-old theory and show that metabolic gradients work hand-in-hand with genetic&signalling instructions to shape the embryo. Glucose isn't just an energy source, it acts as a major conductor of the body plan🍬 https://t.co/mfx6Hk7nma
nature.com
Nature - Two waves of glucose metabolism provide distinct ERK-mediated cellular signals during gastrulation, which regulate cell fate and specialized cellular functions that are necessary for...
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Our former post doc is starting her lab at Sloan Kettering. She's brilliant, kind, creative, and works at the interface of biophysics, cell biology, imaging and immunology, studying tissue infiltration. Very exciting projects. Apply to work with her!
🪰🔬🦠Happy starting my "Cell immigration" lab at fantastic @MSKCancerCenter!! #microscopy, #modelling #Drosophila #organoids. Looking for postdocs, students - come join us🫐 here in NYC
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Drosophila colleagues: Nominate yourself or others for positions on the North American FlyBoard, Trainee Reps, ADRC Plenary/Keynote Speakers, Platform Chairs. Find the GSA email from 9/30 with subject "Share your interest in volunteering with FlyBoard". Pls retweet #Drosophila 🪰
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Great to see my @UclaMcdb colleague Pavak Shah sitting in the front row! Hope you enjoyed Vienna!
It’s a wrap! EvoWorm2024, hosted by IMBA, welcomed 114 attendees and included 43 posters and 50 talks, as well as three workshops on topics ranging from effective scientific communication to nematode sequencing. Thank you to all the attendees and organizers. #evoworm2024
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