Siddhartha Kar
@siddhartha_kar
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associate professor, University of Cambridge | research group leader, Early Cancer Institute | genetic epidemiology for cancer prevention and early detection
Calcutta / Cambridge
Joined June 2013
What protects individuals from developing blood cancers? Thrilled to share my work in @bloodgenes lab, describing inherited resilience protecting blood stem cells from clonal hematopoiesis by modifying RNA regulation. 🧵👇(1/n) https://t.co/PNaCHa4D4k
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Delighted to share our work on clonal hematopoiesis #CH out now in @NatureGenet. We revealed ancestry as a risk factor for CH 🧵 @ASTRAZENECAUK @Cambridge_Uni
https://t.co/4Raaujn3In
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Really fed up with ITV News. I did a pre-recorded interview in which I expressed strong scepticism about the 'coffee only good in the morning' story. But they cut all that out, leaving me apparently supporting their credulous story. I really should not be so naive.
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Why do news outlets keep promoting clickbait dietary epidemiology findings when they’ve been shown to be spurious so often? It was dark chocolate b4 xmas, coffee this morning and milk this evening.
Really fed up with ITV News. I did a pre-recorded interview in which I expressed strong scepticism about the 'coffee only good in the morning' story. But they cut all that out, leaving me apparently supporting their credulous story. I really should not be so naive.
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If you’re at #ASHG2024 #ASHG24 come to the platform session on cardiovascular genetics! 🫀 I’ll present our study using an AI-based phenotype to improve rare variant discovery of coronary artery disease. See paper: https://t.co/Swfwi4nt6W 📍room 401 ⏰ Wed. 8:30 am
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Very excited to share our preprint led by @NakaoTetsushi @skoyamamd examining the determinants & clinical outcomes of leukocyte telomere length in the U.S. with stark geographic differences! https://t.co/z62sFbCrRE
@medrxivpreprint Hear more about this from @NakaoTetsushi at
🚨📣 Thrilled to share our new preprint exploring leukocyte telomere length (LTL) across ~242,500 whole genome sequences in @AllofUsResearch! https://t.co/S6MKQ4bs20 What did we find? A thread 🧵 (1/11)
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📢📢if you're in Denver this week for #ASHG24, be sure to attend the🎇platform talk🎇by my PhD student, the wonderful⭐George Richenberg⭐, at 8.15 am on the final morning of the conference - Saturday 9th November - at the Four Seasons Ballroom 2&3👇
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Thrilled to be in Denver with 14 colleagues from @AstraZeneca’s Centre for Genomics Research, ready for 5 days of human genomics #ASHG24 The perfect chance to learn about how genomics is transforming drug discovery! Here’s a thread of our presentations - see you there 😀
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Thrilled for #ASHG24. Please check out the cool work from our group and collaborations! Lots of exciting methods for large scale analysis of genetic data 😁
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📢📢if you're in Denver this week for #ASHG24, be sure to attend the🎇platform talk🎇by my PhD student, the wonderful⭐George Richenberg⭐, at 8.15 am on the final morning of the conference - Saturday 9th November - at the Four Seasons Ballroom 2&3👇
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🚨 Preprint 🚨 SSRI #antidepressant users report on whether drugs ‘helped’ them. In @uk_biobank’s 2nd Mental Health Q, - 20k respondents reported on - 4 SSRI antidepressants, answering ‘yes’ or ‘no’ to whether specific drugs helped What do these reports capture? 1/7
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In the latest study from my PhD & @CanGeneCanVar programme, published in @jco_asco, we looked at Risks of Second Cancers in Female and Male Breast Cancer Survivors carrying BRCA1 & BRCA2 pathogenic variants (PVs) using linked NHS data: Paper: https://t.co/BnPNSGO37S
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“Everywhere and Nowhere: Why massive cohort studies have failed to identify more modifiable causes of disease”- in person & online talk @UCLHealthPublic 21st Nov 5pm, registration below. Suggestions for turning this situation around will be discussed https://t.co/xRRZavEEEb.
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We are re-advertising for an exciting 3-yr postdoc post at @imperialcollege using molecular #epidemiology to understand adiposity-driven pancreatic #cancer. Competitive salary and hybrid working options. Deadline 4/11. Email if interested! Pls retweet🙏 https://t.co/a9lkof1DX3
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Interested in combining genetic epidemiology with other methods to identify modifiable causes of disease? If so a research fellow post with @mrc_ieu with @explodecomputer and me now available
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#Endometriosis: addressing the roots of slow progress Governments need to formulate plans that not only include measurable targets & interventions across the care pathway but also address the need to change the culture around women, pain & periods. 🔗 https://t.co/bajgcETOhX
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New #preprint! Using genetic algorithms for GWAS functional interpretation. On @researchsquare: Genome wide association studies are enriched for interacting genes
researchsquare.com
Background: With recent advances in single cell technology, high-throughput methods provide unique insight into disease mechanisms and more importantly, cell type origin. Here, we used multi-omics...
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A new senior lecturer post in cancer epidemiology @BrisCancerEpi working within a fantastic team
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‼️ It's today! #ECISymposium2024 with exciting keynote talks from @TitusBrinker and @leedham_simon. Also presentations from Group Leaders @siddhartha_kar and Danielle Harper and early career researchers @__AFonseca, @GiovannaMantica and @williammcgough_ 👇
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