Shawn Lee
@shawnleehr
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Paediatric hemato-oncologist | Clinician-Scientist | Childhood leukemia and genomics 🧬 St Jude Children’s Research Hospital | National University of Singapore
Singapore
Joined June 2016
Excited to share our newest paper in @JCO_ASCO!. Where we define the most optimal hyperdiploid definition, and also evaluate ex vivo drug sensitivities, with chromosome-specific associations, across the largest subtype of childhood ALL.
ascopubs.org
PURPOSEHigh hyperdiploidy, the largest and favorable subtype of childhood ALL, exhibits significant biological and prognostic heterogeneity. However, factors contributing to the varied treatment...
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The most fun image & video creation tool in the world is here. Try it for free in the Grok App.
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RT @Junjyang: And we are actively recruiting motivated postdocs to work on this massive dataset, a lot to mine with new biology to follow u….
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Also made possible for me through the support of @NUSResearch @NUSMedicine and NMRC Singapore.
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Honored to share our study on drug sensitivity in childhood ALL and its impact on prognosis. Hot off the press in Nature Medicine! @StJudeResearch.
Pharmacotyping analyses of large cohorts of pediatric acute #lymphoblastic #leukemia identify correlations between drug sensitivities and clinical outcomes across different #genomic subtypes. @shawnleehr @Junjyang @StJudeResearch .
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RT @Junjyang: Start 2023 with a bang: new paper on ALL pharmacogenomics in @NatureMedicine, studying 805 kids of 23 subtypes for ex vivo re….
nature.com
Nature Medicine - Pharmacotyping analyses of large cohorts of pediatric acute lymphoblastic leukemia identify correlations between drug sensitivities and clinical outcomes across different genomic...
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RT @Junjyang: Proud of @shawnleehr and Wenjian for leading this massive collaboration with Dr. Bill Evans @mrelling @StJudeResearch.
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RT @StJudeResearch: Scientists from St. Jude performed the largest study yet examining drug sensitivity in childhood acute lymphoblastic le….
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RT @StJudeResearch: In 2022, our scientists advanced research in hemoglobin expression, cancer survivorship, CAR-T, COVID-19, #smFRET and m….
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RT @StJudeResearch: To wipe childhood cancer off the map, scientists must chart its genomic landscape. Earlier this year, they created a ro….
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RT @Junjyang: Kudos to twitterless Seth Karol and Wenjian Yang, and @KeitoPharmd @mrelling!! The protective effect of TPMT specific to the….
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RT @StevenXGe: Happy holidays! Introducing an AI-powered app that lets you chat with your data in English! RTutor….
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RT @Junjyang: Glad to share our recent work on pharmacogenomics of immunotherapy resistance. It is all about leukemia interaction with host….
science.org
Genome wide CRISPR screen identifies CD58 as the key regulator of blinatumomab resistance in Acute Lymphoblastic Leukemia.
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RT @SherifAbdlhamed: Two amazing studies by @StJudeResearch researchers were featured in the Best of ASH22 @ASH_hematology. Way to go! @Pol….
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RT @CMullighan: Fantastic to see our collaborative studies with @COGorg @CHOPCancerCntr @Junjyang showing the power of large scale integrat….
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RT @POTUS: Today, I sign the Respect for Marriage Act into law – a landmark civil rights bill that honors the courage and sacrifice of gene….
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RT @Junjyang: @yixuanxiaozhu presenting her exciting data on PAX5/CD58 mediated blinatomomab resistance in B-ALL. #ASH2022 DM me if you are….
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RT @ALL_Hub_: CONGRESS |#ASH22 Shawn Lee, @StJudeResearch highlights results from the drug sensitivity analysis of pediatric ALL subtypes,….
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