Roshan Padmanabhan
@roshan_818
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Lead, Bioinformatics Scientist, Trailhead Biosystems Inc.
Ohio, USA
Joined June 2008
RT @BiologyAIDaily: PROTEOMIZER: Leveraging the Transcriptome-Proteome Mismatch to Infer Novel Gene Regulatory Relations. １．The authors int….
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RT @RaziaAliani: We're about to create the 1st gen of scientists who can't research without AI. And honestly? I'm not sure if that's evolut….
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RT @itsPaulAi: Google has released an open source project for building fullstack agents with Gemini 2.5 🔥. You can run and modify it with R….
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RT @razoralign: uHAF: a unified hierarchical annotation framework for cell type standardization and harmonization h….
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RT @naturemethods: Out today from the Neal lab! An optical pooled cell profiling platform (PERISCOPE) based on Cell Painting and optical se….
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Why probability probably doesn’t exist (but it is useful to act like it does)
nature.com
Nature - All of statistics and much of science depends on probability — an astonishing achievement, considering no one’s really sure what it is.
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RT @StephenQuake: Virtual cell models have the potential to transform biological research. Today @ChanZuckerberg released an initial set of….
chanzuckerberg.com
We’re making it easier for biologists and machine learning researchers to collaborate with cell models that are easy-to-use + build upon to accelerate the next big breakthrough.
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RT @strnr: Gene count estimation with pytximport enables reproducible analysis of bulk RNA sequencing data in Python .
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The Nobel Prize in Physics 2024 - Popular science background -
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diffGEK: Differential Gene Expression Kinetics
biorxiv.org
A defining characteristic of all metazoan organisms is the existence of different cell states or cell types, driven by changes in gene expression kinetics, principally transcription, splicing and...
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RT @emileifrem: My friend and Neo4j CTO @prathle has written an outstanding blog post that summarizes the recent buzz around GraphRAG, what….
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The gut microbiome has a circadian rhythm. Here's how it might affect your health.
livescience.com
Daily fluctuations in gut microbes may have a plethora of effects on the body, but many questions remain.
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Chimeric brain organoids capture human genetic diversity
nature.com
Nature - Cortical organoids made from a mix of stem cells from different donors.
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ESM3 a frontier language model for the life science can generate new proteins with an unprecedented degree of control, and its generation process can be guided by sequence, structure, and function prompts. #GenAI #proteinengineering #llm #bioinformatics.
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"Agents for Science Era" - CellAgent, an LLM-driven multi-agent framework, automates scRNA-seq data analysis, reducing manual labor and ensuring high-quality results. #LLM #scrnaseq.
biorxiv.org
Single-cell RNA sequencing (scRNA-seq) data analysis is crucial for biological research, as it enables the precise characterization of cellular heterogeneity. However, manual manipulation of various...
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