Ryan Nett
@rnett42
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Assistant Professor @MCB_Harvard. Working to understand plant metabolism and its role in biology. Avid mushroom hunter.
Cambridge, MA
Joined June 2021
Our work on the biosynthesis of huperzine A, a neuroactive alkaloid from clubmosses, is now published in @Nature!. Beyond pathway elucidation, we make the surprising discovery that carbonic anhydrase-like enzymes are crucial in alkaloid scaffold formation.
nature.com
Nature - We show how neuroactive alkaloids from clubmosses are biosynthesized, which reveals an unexpected role for carbonic anhydrase-like enzymes in alkaloid scaffold formation.
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RT @aribidopsis: It was really wonderful to see @rnett42 Ryan in-person after 2+ years and visiting his lab, greenhouse, and department @MC….
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RT @mehran_plantsci: My lab is moving! Excited to join @UtscBiology + @UofT Cell & Systems Biology on Sept 1st. Grateful to @mcgillu coll….
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RT @MCB_Harvard: Wendy Valencia Montoya – Bridging Natural History and Molecular Biology @wendyssae @NBellono @RachelleGaudet @HarvardOEB @….
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Cool new story by Colin Kim @cyhkim (current postdoc in my group) from his time as a grad student in Jing-Ke Weng's lab. Great example of combining plant genomics and biochemistry to understand enzyme evolution/neofunctionalization!.
science.org
Moonseed evolved rare chloroalkaloids via stepwise mutations that rewire an ancestral oxidative enzyme into a halogenase.
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RT @ScienceAdvances: This common moonseed produces a rare, halogenated molecule, offering an opportunity to study the genomic basis for the….
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RT @pewtrusts: 🎉Congrats to our 2025 biomedical scholars and fellows! . These 37 early-career scientists are embarking on innovative resear….
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Truly honored to be selected as a Pew Biomedical Scholar! . Thank you to past/present mentors for your support and to everyone in my lab for your help in advancing our understanding of plant chemistry. Excited to meet the other Pew scholars! @pewresearch .
pew.org
PHILADELPHIA—The Pew Charitable Trusts today announced the 22 researchers joining the Pew Scholars Program in the Biomedical Sciences. These early-career scientists will receive four years of funding...
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RT @MCB_Harvard: Ryan Nett Named Pew Scholar for Innovative Research on Plant-Derived Molecules @rnett42 @RachelleGaudet @mlgredler @DulacL….
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RT @conor_mcclune: A truly enabling new approach by Tara Lowensohn, @WillCody_12 and @Sattely_lab to probe plant genetics at scale. Single….
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RT @Stanford_ChEMH: 'The vaccine we all wear' .In @ScienceMagazine, Postdoc @DjenetBousbaine writes about her work in Institute Scholar @mf….
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RT @JamieBlum7: I am thrilled to announce that I am launching my lab at the Salk Institute in September! The Blum lab will study the physio….
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RT @MCB_Harvard: You Are What Your Great-Grandparents Ate .@RachelleGaudet @DulacLab @VMurthyLab @JeeyunC @mlgredle….
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RT @DjenetBousbaine: It’s truly an honor to receive this year’s @ScienceMagazine Noster Microbiome prize. Here’s my essay on how we can en….
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RT @MCB_Harvard: Carolyn Elya Receives Prestigious Klingenstein Fellowship in Neuroscience @RachelleGaudet @mlgredler @MicrobiomeTcell @rne….
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RT @conor_mcclune: Today in @Nature we report a systematic strategy to activate & identify gene sets in plants. We identify 8 new genes fro….
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RT @yokoyama_ryo: Ipecac alkaloid biosynthesis in two evolutionarily distant plants @nchembio.
nature.com
Nature Chemical Biology - Ipecac alkaloids are plant-derived compounds historically used to induce vomiting. Here the authors elucidate how two evolutionary distant plant species have evolved to...
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RT @MPlantPCom: Rising Stars in Plant Sciences 2025 (RSPS2025) | Finalist Oral Presentation Contest | Jun 4 12:55-15:30pm & Jun 5 13:00-15:….
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RT @MCB_Harvard: Recognizing Excellence in Mentorship: 2025 MCB Mentorship Award Recipients @claireangj @karalmckinley @cyhkim @LabWhipple….
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RT @psnaofficial: 📢🌱Join leading experts in plant science this June at York University, Toronto:. Elizabeth Sattely (Stanford).Mark Lange (….
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