eIisa
@mildTin
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Looking forward to a nearish future without disease, acute or chronic. Millions with Long Covid and ME/CFS working and waiting to get our lives back
Australia
Joined June 2013
Anti aging breakthrough Researchers have reported an advance that may reshape approaches to cellular ageing and tissue degeneration. New nanotech rejuvenate old and damaged human cells by replacing their mitochondria Researchers at Texas A&M have developed MoS₂ "nanoflowers"
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ME/CFS & Long COVID patients: we need your help! We’re validating a new tool to measure post-exertional malaise (PEM). Current questionnaires don’t capture its severity or impact. Your input changes that! English: https://t.co/OIRL7K0y6V German: https://t.co/Ya90kUbyZd 🫶🙏
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Ever since I learned the shelf for mitochondrial targeting drugs is bare and dusty I've been super excited at any mention of a mito drug in development
NIH researchers found that IVO-21, a new oral drug, stabilizes mitochondria and calms thromboinflammation in mice. It may safely treat the metabolic and vascular damage seen in long COVID.
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NIH researchers found that IVO-21, a new oral drug, stabilizes mitochondria and calms thromboinflammation in mice. It may safely treat the metabolic and vascular damage seen in long COVID.
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At Institut Fournier in Paris, 19 long COVID patients with severe GI symptoms took maraviroc and pravastatin. After 3 months, 78% showed major improvement, linked to fewer blood microclots and less viral material in platelets
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💪 Starkes Zeichen für den Einsatz gegen Long COVID & ME/CFS: Zum Start der „Allianz postinfektiöse Erkrankungen: Long COVID & ME/CFS“ tauschten sich Bundesgesundheitsministerin @ninawarken & Bundesforschungsministerin @DoroBaer mit Betroffenen sowie Expertinnen & Experten aus.
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3rd Long COVID International Conference 2025 🧵below
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5 science breakthroughs this week (🧵) 1. Lupus remission with cell therapy 18 patients with longstanding, treatment-resistant lupus were treated with B cell-depleting natural killer cells (CD19 CAR NK-cells) There results were pretty amazing: every patient was able to stop
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Shionogi (makers of ensitrelvir) is testing a long acting drug as a sarscov2 prophylaxis- currently recruiting
Phase 1 clinical trial for S-892216, a Pre-Exposure Prophylaxis (PrEP) for COVID-19 is recruiting in Kansas and Utah in the US. https://t.co/5rGp0OFa7C 1/
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More people with #Long COVID are now eligible for the ADDRESS-LC trial on Bezisterim! (1/2) The trial is now open to those who: -have had #Long COVID for more than 2 years -are taking LDN (up to 4.5mg per day) -have ADHD, if not treated with stimulants -are up to 69 years old
2 new sites are enrolling for the #LongCovid ADDRESS-LC trial on bezisterim: Mount Sinai (NY) & UCSF (SF)! Bezisterim is an investigational drug that has been studied in neurological disorders, including Alzheimer’s. Find a site near you: https://t.co/yS2GiXjCfV
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BREAKING: New machine learning study identifies distinct Long Covid symptom endotypes across four major cohorts 👉🏻PolyBio-supported research uses questionnaire-based machine learning to successfully identify global Long Covid endotypes 🧵
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Forschungsministerin Dorothee Bär und Gesundheitsministerin Nina Warken geben morgen ein gemeinsames Pressestatement zu Long COVID und ME/CFS ab. 👉 Den Livestream könnt ihr ab 15 Uhr direkt hier auf unserem X-Kanal verfolgen.
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Implications ➡️ This work maps a step-by-step causal chain: CHCHD2 mutation → mitochondrial failure → metabolic shift → ROS buildup → alpha-synuclein aggregation → Parkinson’s pathology ➡️ It supports the idea that mitochondrial defects may underlie many forms of
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NIH researchers tracked 3,659 US adults after COVID and found 5% had persistent Long COVID symptoms for 15 months while 12% had ongoing symptoms that fluctuated. Only 19% of those affected showed signs of recovery within a year. https://t.co/EFAhrycWP7
nature.com
Nature Communications - Long COVID has heterogeneous presentation and clinical trajectories are not well defined. Here, the authors define trajectories using data from a prospective cohort study in...
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Morgane Bomsel at Polybio's Fall Symposium - 66% of LC patients had spike detectable in plasma. Recovered patients had no spike, and spike is independent of vaccination
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Viral particles in nearly all post-covid samples!! Detectable in blood!
2/ Analysis of the first set of samples found SARS-CoV-2 viral particles in nearly all post-COVID samples
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#polybiofallsymposium2025: Dr. Shannon Stott described the ongoing testing of a microfluidics device detecting whole viral particles in Long Covid patient samples. 100 samples are currently being assessed for viral load, to determine if levels correlate with clinical
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NEW: "A significant step toward understanding viral persistence." Michael Peluso announced a new #LongCOVID trial, COMBAT-LC, that will test the combination of Pemgarda & Paxlovid. Check out our full live blog of the Polybio Fall 2025 symposium! https://t.co/PJaVKImv0u
thesicktimes.org
Leading Long COVID and related disease researchers are set to present updates to their work today at the PolyBio Research Foundation’s Fall 2025 Symposium. PolyBio supports some of the most highly-...
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A groundbreaking paper by @younis_sh1 et al. @stanfordimmuno provides an answer to the long-standing question about how EBV infections are linked to lupus. A short thread to explain the key findings. (1/) https://t.co/dUpz19IjEv
science.org
Epstein-Barr virus reprograms autoreactive B cells as antigen-presenting cells to promote pathogenic antinuclear T and B cell responses in lupus.
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