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Mike Nikolaev Profile
Mike Nikolaev

@mike_nikolaev

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Scientist @Roche @IHB_Research, Alumni @TheLutolfLab, @EPFL Organoids bioengineering & microfabrication 👨‍🔬🧗🏔⛷

Switzerland
Joined March 2020
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@mike_nikolaev
Mike Nikolaev
1 year
I am thrilled that our new paper was published today! 🎉🎉🎉.We have developed human mini-colons and mini-intestines that closely recapitulate in vivo tissue diversity of mature and functional cell types, long-term homeostatic culture and physiological cell turnover! .🧵
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@mike_nikolaev
Mike Nikolaev
4 months
RT @BeumerJoep: We are searching for 2 talented MSc students to join the group! If you are interested in using advanced organoid models to….
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@mike_nikolaev
Mike Nikolaev
11 months
RT @GoogleDeepMind: We’re presenting AlphaProteo: an AI system for designing novel proteins that bind more successfully to target molecules….
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@mike_nikolaev
Mike Nikolaev
1 year
RT @organoidscience: If you haven't already, then check out this @Nature study from @IHB_Research scientists and their collaborators! ✅ . T….
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@mike_nikolaev
Mike Nikolaev
1 year
RT @NatureBiotech: Patient-derived mini-colons enable long-term modeling of tumor–microenvironment complexity https….
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@mike_nikolaev
Mike Nikolaev
1 year
Excited to share our latest paper that advances human mini-gut chip technology! . Leveraging laser ablation and hydrogel microstructuring technologies, we can now reconstruct realistic organ-level microenvironments. This organ-on-chip integrates patient cancer cells with their.
@TheLutolfLab
Matthias Lutolf
1 year
Following our recent breakthrough on mouse mini-intestines for ex vivo tumor development, we asked ourselves: can this technology be applied to cells from cancer patients? We are excited to announce the answer to this question in our latest publication:
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@mike_nikolaev
Mike Nikolaev
1 year
RT @Roche: 🔧 Engineering New Gut Models 🔧 .Innovative organoid-on-a-chip merges stem cell biology with advanced bioengineering for more acc….
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@mike_nikolaev
Mike Nikolaev
1 year
Congratulations to @olga_mitrofan, @NicoBroguiere , @TheLutolfLab, @GrayCampLab, @EPFL_en, @epflSV, @IHB_Research and all co-authors!.
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@mike_nikolaev
Mike Nikolaev
1 year
We believe that realistic bioengineered mini-organs have great potential to model intestinal physiology and function in vitro and will accelerate the drug development process.
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@mike_nikolaev
Mike Nikolaev
1 year
In this work, we are advancing the use of a new class of organ-on-chip devices that we introduced earlier with mouse mini-guts. Over the past few years, we have continued developing the unique toolkit of advanced bioengineering technologies and focused on growing human.
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@mike_nikolaev
Mike Nikolaev
1 year
Additional cell types such as fibroblasts, immune cells and microvasculature can be added to the matrix, allowing to study organ level multicellular interactions!
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@mike_nikolaev
Mike Nikolaev
1 year
The biomimicking matrix and tissue-specific microtopography in the core of the chip allows to recreate intestinal epithelium that look and function like real tissue!
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@mike_nikolaev
Mike Nikolaev
1 year
Join our team and contribute to the development of engineered models of intestinal inflammation to study #IBD and derive novel therapeutic approaches. This is a unique postdoc position hosted by the Immunology department within Roche pRED, in collaboration with the
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@mike_nikolaev
Mike Nikolaev
1 year
Excellent @Fusion_Conf #Stemgastro24, lots of insightful talks in a beautiful venue! Great to meet with collaborators for the first time in 3D😉 @kim_bak_jensen.
@olga_mitrofan
Olga Mitrofanova
1 year
Congratulations to @mike_nikolaev for winning the best poster prize! @IHB_Research #stemgastro24
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@mike_nikolaev
Mike Nikolaev
1 year
RT @yulia_navalnaya: Лёша, спасибо тебе за 26 лет абсолютного счастья. Да, даже за три последних года счастья. За любовь, за то, что всегда….
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@mike_nikolaev
Mike Nikolaev
1 year
RT @BorisJohnson: No one can be in any doubt that Alexei Navalny has been put to death by Vladimir Putin - simply because he had the courag….
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