Irina Mikheyeva
@micro_irina
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Manuscript Transfer Editor| ASM 🧫🔬 | she/her
Pittsburgh, PA
Joined July 2019
RT @ASMicrobiology: Don’t miss your chance to present at ASM’s first-ever Global Research Symposium in India! 🌏✨ Join global experts at the….
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What happens to the E.coli outer membrane when it can't efficiently insert proteins? OM asymmetry is lost and mislocalized outer leaflet phospholipids become crucial! . Check out our collab characterizing this process w/ @JiaweiSun19 and KC Huang! .
nature.com
Nature Communications - The outer membrane (OM) of Gram-negative bacteria is an asymmetric bilayer, with phospholipids in the inner leaflet. Here the authors show that a reduction in OM proteins...
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RT @Randi_Guest: Why do Pseudomonas aeruginosa have not one, but two MlaA-like proteins? Turns out that one protein is part of a classic ma….
pnas.org
The outer membrane of Gram-negative bacteria is unique in both structure and function. The surface-exposed outer leaflet is composed of lipopolysac...
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RT @McLellan_Lab: Big day! I'm honored to receive the Norman Hackerman Award from The Welch Foundation. Many thanks to all who helped make….
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RT @TAMU_Biology: The Angela Mitchell Lab wants you to #JoinMyLab! The Mitchell Lab investigates #AntibioticResistance under stress in gram….
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So proud of @Bridges_Bio! Here's a little snippet of his work and a guest appearance by yours truly.
2022 Blavatnik Regional Awards Finalist 🏅 Dr. Andrew Bridges studies the lifecycles of bacterial #biofilms. He uncovered the lifecycle of v. cholerae, the bacteria that causes #cholera @Bridges_Bio @Princeton @cmuscience .@nationalpostdoc #NPAW2022
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RT @hbernstein16: A fully funded postdoctoral position is available to study the assembly of bacterial outer membrane proteins, which are a….
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RT @AlHendiify: One of those mad subtle indicators of how bad things have become is how clear your windshield still is after a road trip.
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Exciting new work from the Silhavy lab!.
pnas.org
The biogenesis of integral β-barrel outer membrane proteins (OMPs) in gram-negative bacteria requires transport by molecular chaperones across the ...
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RT @AMitchellLab: Our latest publication is out in #EcoSalPlus! We review major discoveries made with suppressor mutants, types of suppress….
journals.asm.org
For decades, biologist have exploited the near boundless advantages that molecular and genetic tools and analysis provide for our ability to understand biological systems. One of these genetic tools,...
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RT @GeiselBiofilm: I am looking to recruit 2 postdocs to study surface sensing (PMID:34168081), biofilm maintenance (PMID:33531388), or cdG….
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RT @GeiselBiofilm: Save the date for the 50th-ish anniversary of Microbial Diversity Course, July 30, 2022 at the MBL. A great series of t….
mbl.edu
The Microbial Diversity Course Celebrates 50+ Years in 2022!
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Together, these images represent the highest-resolution microscopy data of live E. coli cells to-date!.
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We can also then perturb OM asymmetry by deleting the mlA/pldA system and show that mislocalized phospholipids form distinct morphology and significantly disrupt the OM.
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LPS islands are phase separated, they merge and divide over time but maintain their approximate lateral positions.
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The OM is densely filled with OM trimeric porins, which form a static imperfect lattice spanning from pole to pole. But there are also protein free regions in the OM. these are LPS islands!.
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Pleased to see our exciting collaboration finally online! We combine our OM genetics expertise with the AFM prowess of the @hoogenboom_lab to characterize E coli OM at nanoscale resolution. A 🧵 .
pnas.org
Gram-negative bacteria are surrounded by a protective outer membrane (OM) with phospholipids in its inner leaflet and lipopolysaccharides (LPS) in ...
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Looking for a postdoc? Interested in microbes? Find membranes fascinating? Come work with us and the absolute legend that is Tom Silhavy!.
The Silhavy Lab at Princeton University is looking for a Postdoc to study envelope biogenesis in Gram-negative bacteria. Apply here if you’re interested:
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