MetAGE - Cluster of Excellence
@metage_coe
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🔬 Interdisciplinary research network exploring the metabolic control of ageing and age-related diseases. From basic science to clinical solutions.
Joined April 2025
🔬 Meet Dr. Brigitte Pertschy – Key Researcher @UniGraz & Head of our Training Unit She studies how ribosomes are built & how this process changes as we age. 💡 Recently awarded a €10M @ERC_Research Synergy Grant for the project 'snoOPERA'! Congrats! #HealthyAging #Ribosomes
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Tobias Madl & coworkers show how FOXO4 keeps scenecent “zombie cells” alive by binding to a disorderd region of p53. Blocking this with FOXO4-DRI initiates killing of aging cells - a potential key to anti-aging therapies. @MedUniGraz #senolytictherapies #healthyaging #metage
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👩🔬Meet our team: Dr. Martina Schweiger from @UniGraz studies how fat and metabolism shape health, aging & disease - from obesity to cachexia. Because having too much or too little fat affects us profoundly! #MetAGE #HealthyAging #Metabolism #adiposetissue
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Good commnication is what truly matters - no matter if young or old, in our body or beyond. What's your take on this? #sciencecommunication #Longevity #agingfinelikewine #MetAGE #agingresearch #metabolicsignaling #communication
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Meet Dr. Thomas Scherer – MetAGE Deputy Director of Research @MedUni_Wien As a clinician, he's not only interested in the mechanisms of age-related diseases, but also to integrate clinical intervention studies into his research. More👉 https://t.co/0NgGtccr7C
#AgingResearch
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Ever feel like your energy just doesn’t bounce back like it used to? It’s not just age. It's your cells losing their metabolic flexibility. Good news: we’re learning how to reverse it. 🔁 Join the conversation on healthy aging! 🧠 #AgingResearch #Metabolism #MetAGE
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🫀Obesity speeds up aging of the heart & vessels – through inflammation, cell stress, & mitochondrial dysfunction: MetAGE researchers @Mah_abdellatif & Frank Madeo have compiled current research. 🔗 https://t.co/JdwX0x4ljC
#MetAGE #HeartHealth #Obesity #AgingResearch #LONGEVITY
academic.oup.com
Abstract. A global obesity pandemic, coupled with an increasingly ageing population, is exacerbating the burden of cardiovascular disease. Indeed, clinical
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Grateful for the insights&exchanges - and excited to keep building connections that support healthy aging across generations. Want to discuss some points? Enter the conversation👇🔗 https://t.co/o4iwEz0Liw
#HealthyAging #MetAGE #LifelongLearning #Innovation #AgingWell #longevity
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✨ Some Takeaways: 🔹 When is “old” old? → mindset vs. reality 🔹 Don't just innovate for, but with older generation 🔹 Interdisciplinary collaboration is key 🔹 Innovation thrives when young & old work together 🔹 Lifelong learning will be essential in an ageing society
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🧠 We recently attended SENovation Styria, hosted by @medunigraz – an event on innovation for healthier aging with voices from science, business & healthcare.
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🎥 How does fat metabolism shape how we age? ORF featured 'MetAGE' in a short TV clip on our research about aging and metabolism in cell models and patients. @UniGraz
@MedUniGraz 📺 Watch here (in German): https://t.co/wr1N5BG8Qe
#healthyaging #longevity #metage
on.orf.at
Erste Details aus dem Landessicherheitsbeirat | Debatte um mehr Jugendschutz im Internet | Aktuelle Krone-Umfrage zeigt FPÖ im Aufwind | Präsentation der Alternative zum Leitspital Liezen | Klasnic...
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👋 Meet Dr. Mahmoud Abdellatif @Mah_abdellatif – MetAGE key researcher @MedUniGraz He studies how aging affects the heart and vessels at the cellular&molecular levels – and how we could slow it down. https://t.co/0NgGtccr7C
#HealthyAging #HeartHealth #AgingResearch
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🫀New publication from our cluster researchers: Blocking fat breakdown - not just eating less - may better treat #obesity-related heart failure (#HFpEF). Fat tissue might hold the key.👇 @simon_sedej @Mah_abdellatif @AndreasZirlik
@UniGraz @MedUniGraz @tugraz
#MetAGE
@CircRes Compendium on Interorgan Crosstalk in #HeartFailure and #Cardiometabolic Diseases @Instckner et al Research Letter "Inhibition of #Adipose Tissue #Lipolysis Treats #Obesity-Related #HFpEF" https://t.co/M7d8YxkUMQ
@simon_sedej @AndreasZirlik @mah_abdellatif
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Not the only, but one reason, why our research is so important 👇 #healthyaging #longevity #metage #metabolicflexibility
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Here's what our research cluster does: We study how aging affects metabolism and vice versa – and what we can do to increase our healthy life span. #HealthyAgeing #MetAGE #ScienceToAction #longevity #translationalresearch
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@rau_thomas from the @MartinaS_lab presents an easy to use approach for whole-mount labeling and quantification of neuron- and vessel-density in adipose tissue in journal of cell science (JCS), @UniGraz
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One of the first publications resulting from our Cluster of Excellence by @MartinaS_lab and colleagues (including this beautiful cover image)! Check it out 👇 #MetAGE #healthyaging #longevity #microscopy #adiposetissue
Our article has been selected to provide the Cover image in the Journal of Cell Science! The beauty of the network of nerves and vasculature in adipose tissue. @sfb_immunomet @rau_thomas @UniGraz
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