Amber Smith, PhD
@mathematista
Followers
1K
Following
2K
Media
82
Statuses
2K
Mathematical Biologist • Model-Driven Experimentalist • Respiratory Infection & Coinfection Pathogenesis
Memphis, TN
Joined April 2014
Read our latest work modeling heterogeneity in human influenza.
Multivariate Host-Pathogen Interactions Driving Heterogeneous Viral Shedding and CD8+ T cell Control of Influenza Virus Infection https://t.co/1TilAIQkss
#medRxiv
0
0
0
SMB President @Flasheff1 and other governance members with @KSMB_SMB2024 organizing co-chair Yangjin Kim at the SMB Annual General Meeting! #smb #ksmb
0
5
16
Super proud to have contributed to this important and first special issue on immunology methods in @naturemethods
.@naturemethods has increasingly focused its attention on methods development in immunology and presents a special issue that highlights methods and technologies that have galvanized immunological research. Editorial: https://t.co/MbyN0saugc Issue: https://t.co/DryhWAFfpC
1
1
7
The immune system is a uniquely dynamic environment. In a Comment, @mathematista discusses how custom-built mathematical models should complement experimental approaches to make immune kinetics more predictable. https://t.co/LfDL4NEcVR
0
3
12
#tldr on the methods: ✔️ customized models balance feasibility & usability ✔️data 🔁 models ✔️ modeling intracellular 🔗 cellular mechanisms = getting crafty ✔️ integrate clustering methods & mechanistic modeling …🤯➡️…immune digital twin
2
2
2
#tldr Mechanism 🤝 Mathematical model Correlation 🤝 AI/machine learning/deep learning Predicting immune kinetics = modeling the (nonlinear) feedback/forward loops Individualism ≠ individualized outcomes (ty✨nonlinearities✨) ➡️ need to rethink correlative biomarkers
1
1
2
Read my latest article on making immunology more predictable using custom-built mathematical models, published with @SpringerNature in @naturemethods
https://t.co/f4KPHI2NkT
4
17
84
New research: Toward mechanistic medical digital twins: some use cases in immunology https://t.co/nsS2kwJvZj
#digitalhealth
frontiersin.org
A fundamental challenge for personalized medicine is to capture enough of the complexity of an individual patient to determine an optimal way to keep them he...
0
2
1
🌟 Inviting early career researchers to showcase your mathematical model of a biological system at the BioModels' Model of the Year 2024 competition! Submit your exciting work, gain recognition, and win cash prize! Deadline: Feb 29, 2024. More info: https://t.co/x65oakyWRm
0
13
21
🌟 Our article on the Model of the Year 2023 is out! Check out the winners' innovative work in #FrontiersinSystemsBiology: https://t.co/PdtqZMBAsa 🏆 Dreaming of having your model in the spotlight? ☀️ Apply now for MOY2024 https://t.co/x65oakyp1O ⌛️Deadline: 29th Feb 2024!
1
7
17
🔊 #smb2024 joint annual meeting of KSMB and @SMB_MathBiology 📍 Konkuk University, Seoul, Republic of Korea 🗓️ June 30 - July 5, 2024. Abstracts due: Mini symposium : Oct 20 - Nov 30 Contributed talks/posters: Nov 20 - Dec 31 https://t.co/dQ34H0dIlp
0
18
19
Excited to share that our recent #OpenAccess article with @lab_craig @adrianne_jenner @pennymorel @mathcourtney @rosie_aogo is among the most cited papers in #PLOS Pathogens in 2022. Read the article at
journals.plos.org
Author summary Understanding of the diversity of immune responses to SARS-CoV-2 infections is critical for improving diagnostic and treatment approaches. Identifying which immune mechanisms lead to...
2
5
10
Successful @SMB_MathBiology Board Meeting in some old school swag to kick off #smb2023 Here’s to a great week 🎉
1
7
39
Go check out our latest pub on viral-viral coinfections. We used models to assess the possible mechanisms resulting in observed viral load and severity differences for RSV, rhinovirus, or SARS-CoV-2 coinfection with influenza. 🦠
❓How Interactions during Viral–Viral Coinfection Can Shape Infection Kinetics❓ by Lubna Pinky et al. https://t.co/0cUWkyKDqY
@mathematista
1
1
13
New preprint from our group on viral-viral coinfections. We used a data-driven modeling approach to predict mechanisms for influenza coinfection with RSV, rhinovirus, or SARS-CoV-2. @Lubna__Pinky
How Interactions During Viral-Viral Coinfection Can Shape Infection Kinetics https://t.co/kH61m7C7lB
#biorxiv_sysbio
1
3
4
Phenotype ➡️ Genotype with Clinical Isolates of SARS-CoV-2
🔎Taylor et al. investigated the #replication, innate #immune response, and #pathology of closely related, clinical variants of #SARS-CoV-2 circulating during the first wave of the #pandemic: https://t.co/JxWZfBmWBW
0
0
1
@SMB_MathBiology Annual Meeting is just 5 months away! 📍The Ohio State University 📆 July 16-21, 2023 Mini-symposia deadline: March 6th
0
4
6
In the last two years 0 of the 6 @ANZIAMnews award winners have been women. Over the last 5 years only 2/15 have been women. And it only gets worse the further it goes back. Let’s make sure us men nominate all the rocking women in applied math next year. No excuses #anziam2024
0
5
28