Pablo M. Garcia-Roves
@m_roves
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Scientist, healthy living, energy metabolism, mitochondria, lifestyle, exercise, university, research.
Spain
Joined July 2020
@davisis79 Many thanks @davisis79 . Proud of Pau. Great dissertation. Many thanks @mardelmala, @AntonioZorzano, @Amaia_777 and @VillenaLab. And special thanks to all our collaborators that contributed to this work
biorxiv.org
Metabolic plasticity is the ability of a biological system to adapt its metabolic phenotype to different environmental stressors. We used a whole-body and tissue-specific phenotypic, functional,...
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RT @Madam_Mito: Pleiotropic effects of mitochondria in aging | Nature Aging
nature.com
Nature Aging - This Review provides an update on the pleiotropic effects of mitochondria in aging and discusses how defects in mitochondrial stress pathways contribute to the decline in cellular...
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RT @KevinMurachPhD: Prioritizing skeletal muscle health for successful aging @OpenAccessGov #myotwitter “The beneficial effects of exercise….
openaccessgovernment.org
Kevin A. Murach talks us through prioritizing skeletal muscle health for successful aging, beginning with a primer on skeletal muscle aging
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RT @NatMetabolism: #Throwback. REVIEW | T Nguyen & @CorveraLab. Adipose tissue as a linchpin of organismal ageing.
nature.com
Nature Metabolism - Nguyen and Corvera review distinct changes that occur in adipose tissue during ageing, discuss potential mechanisms by which these changes impact whole-body metabolism, immunity...
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RT @Gonzalez_JT: 🚨 3-year Post-doc opportunity at the Centre for Nutrition, Exercise and Metabolism, @CNEM_Bath @UniofBath . Opportunity to….
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RT @DrDylanThompson: New Research Associate opportunity in nutrition and metabolism at @UniofBath funded by @BBSRC - closing date 20th Augu….
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RT @NatMetabolism: #Throwback. REVIEW | L Ferrucci, D D’Amico et al. Mitophagy in human health, ageing and disease.
nature.com
Nature Metabolism - This Review discusses the role of mitophagy in cellular and organismal health and disease, with a specific focus on human ageing and evidence obtained in clinical studies.
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RT @cell_club: Mitochondrial origins of the pressure to sleep | Nature
nature.com
Nature - Research on Drosophila neurons shows links between the need to sleep and aerobic metabolism, indicating that the pressure to sleep may have a mitochondrial origin.
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RT @NatMetabolism: Mitochondrial age-classes expand the heterogeneity of tissue-resident stem cells
nature.com
Nature Metabolism - During cell division, a subset of intestinal stem cells (ISCs) inherits old mitochondria that increase intracellular α-ketoglutarate levels. α-Ketoglutarate...
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RT @D_Morales_Alamo: New study reveals targeted remodelling of the adipose tissue niche in obesity and after weight loss, highlighting pote….
nature.com
Nature - An atlas study of adipose tissue in people with obesity undergoing weight loss and their lean counterparts reveals that weight loss reduces cell senescence but cannot reverse all the...
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RT @Pluchinolab: Plasma proteomics links brain and immune system aging with healthspan and longevity.
nature.com
Nature Medicine - In a large-scale proteomic study of biological aging of 11 organs from 44,498 individuals in the UK Biobank, the biological ages of the brain and immune system emerged as strong...
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RT @Madam_Mito: pDCs drive immunopathology by sensing oxidized mitochondrial DNA | Nature Immunology
nature.com
Nature Immunology - Plasmacytoid dendritic cells are known for their ability to produce large amounts of type I interferons, which can contribute to autoimmunity. Research now shows that this...
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RT @Madam_Mito: Molecular machineries and pathways of mitochondrial protein transport | Nature Reviews Molecular Cell Biology https://t.co/….
nature.com
Nature Reviews Molecular Cell Biology - Mitochondrial proteins encoded in the nucleus are imported into mitochondria by specialized transport machineries located in the outer and inner...
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RT @NatMetabolism: Multi-omic analysis reveals transkingdom gut dysbiosis in metabolic dysfunction-associated steatotic liver disease https….
nature.com
Nature Metabolism - High-resolution multi-omic profiling indicates widespread gut dysbiosis in individuals with MASLD, also affecting the virome, and reveals microbial signatures that can classify...
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RT @OroborosI: Use pathway-control ratios and efficiencies to quantify N-, S-, and NS-pathway contributions under convergent electron flow.….
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RT @NatureRevEndo: New content online: Adipose tissue ageing: implications for metabolic health and lifespan https:….
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