Lonnie Pyne
@lp7777777
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Assistant Professor, Nephrologist, McMaster University
Hamilton, Ontario
Joined June 2010
"Tweet storm" on the topic of albuminuria lowering as a surrogate endpoint and why it's a bad idea. As requested by @S_brimble . Fair warning this isn't going to be short.
An important milestone and cause for celebration: “Change in Albuminuria and GFR as End Points for Clinical Trials in Early Stages of Chronic Kidney Disease”.
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RT @turbo_dc: Check out our latest publication in @NDTsocial on the meta-epidemiology of heart failure events in RCTs for adults receiving….
academic.oup.com
ABSTRACTBackground and hypothesis. Heart failure is characterized as cardiac dysfunction resulting in elevated cardiac filling pressures with symptoms and
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Hi. Lonnie Pyne. Nephrologist from Hamilton, Ontario, Canada at McMaster University.COI - one of the authors.#NephJC.
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Lonnie Pyne.Nephrologist in Hamilton, Ontario, Canada at McMaster University.COI - one of the authors. #NephJC.
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RT @kidney_boy: The next #NephJC will be about this Loni Pyne paper that @Nephro_Sparks discusses in the ASN kidney translation podcast.….
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RT @Nephro_Sparks: The first episode of the new @ASNKidney Kidney Translation podcast is live . PPI, Antivirals, and Cough Syrups: Nephroto….
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RT @AJKDonline: Sex and Gender in Randomized Controlled Trials of Adults Receiving Maintenance Dialysis: A Meta-epidemiologic Study . https….
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RT @turbo_dc: We recently published a meta-epidemiologic study of RCTs in maintenance dialysis published in high-impact medical, nephrology….
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RT @AALJaishi: It took 3+ years of study design and preparation and 4 years of study follow-up: The #MyTEMP trial is published in the @TheL….
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RT @mvaduganathan: Another win for IV iron in HF! Now with a different iron formulation. #IRONMAN now out in @TheLancet with #AHA22. http….
thelancet.com
For a broad range of patients with heart failure, reduced left ventricular ejection fraction and iron deficiency, intravenous ferric derisomaltose administration was associated with a lower risk of...
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I’m also a sad confused chlorthalidone-bro. Need deep dive to explain…and also save face from my aggressive HCTZ bashing.
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Come for the fantastic presentation on diuretic management in HTN by internal medicine residents extraordinaire Tamoor Afzaal (@TamoorAfzaal), Curtis Sobchak (@CurtisSobchak), and Alex Grindal. Stay for the well-deserved HCTZ bashing!.
Incase you missed the @HamHealthSci #MedicalRounds on #Hypertension and Chronic #kidneydisease, now available at #MedEd @McMasterU #BrighterWorld
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Lonnie Pyne from Canada joining in #NephJC. No COI. aside from a firm belief that proteinuria lowering isn't a valid surrogate, even when part of a nice sounding composite outcome :).
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RT @AJKDonline: Allopurinol: Good for Gout But Not for Preventing Loss of Kidney Function. (FREE). @lp7777777 @last….
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