Nephrology Journal Club
@NephJC
Followers
35,849
Following
1,252
Media
9,638
Statuses
49,356
A twice monthly nephrology journal club that meets on Twitter. Hashtag #NephJC
twittersphere
Joined April 2014
Don't wanna be here?
Send us removal request.
Explore trending content on Musk Viewer
namjoon
• 361397 Tweets
メイドの日
• 183461 Tweets
भगवान परशुराम
• 126176 Tweets
WIN NESPRESSO SUMMER
• 109599 Tweets
#ÖğretmenTekYürek
• 84979 Tweets
メイドさん
• 76762 Tweets
علي النبي
• 69770 Tweets
メイド服
• 59080 Tweets
#ArvindKejriwal
• 37887 Tweets
अरविंद केजरीवाल
• 36778 Tweets
सुप्रीम कोर्ट
• 35931 Tweets
Hayırlı Cumalar
• 35273 Tweets
太陽フレア
• 30746 Tweets
IS:SUE
• 30681 Tweets
通信障害
• 28214 Tweets
オーロラ
• 25691 Tweets
चुनाव प्रचार
• 24943 Tweets
RTTT
• 24749 Tweets
オレカバトル
• 22804 Tweets
Lunin
• 18208 Tweets
#SupremeCourt
• 17716 Tweets
ポケミク
• 16990 Tweets
マスターソード
• 15993 Tweets
Pinned Tweet
A bit later is better than never. Here is the distilled and refined
#NephJC
summary of this week on chapters 1, 2, and 6 from
@goKDIGO
chronic kidney disease guideline
✍️By
@stephanietr612
and
@DrMedhavi_G
⚔️Are you ready for the feisty discussions?
1
20
41
T0: HRS-1 is the diagnosis we hate to make, given it’s prognosis (untreated = median survival 2 weeks)
Here are the criteria for diagnosing HRS-1 (under the alternative name of HRS-AKI)
Do the criteria work? What’s good, what’s bad?
Image courtesy of
@drkeithsiau
#nephjc
13
70
184
Take a look at the amazing
#visualabstract
made by
@divyaa24
🎨
@goKDIGO
LN guideline has already started some controversies. ⚔️ If curious or if you'd add some perspective, come to
#NephJC
chats
💬Chat 1: 9 pm EDT, Feb 6
💬Chat 2: 9 pm IST, Feb 7
0
63
147
1/
#Tweetorial
#NephJC
#Hypernatremia
Reviews and guidelines say to correct hypernatremia in adults by no more than 10 mmol/L per day. This is based on little hard data, has little support in literature and may be harmful
4
81
137
This week we dive deep into Roxadustat for CKD-ND and Dialysis Its finally here...epo in a pill! Does roxa live up to the hype? -
1
57
122
Apparently, these SGLT2i drugs are pretty good for the kidney -
1
49
124
Freely Filtered 020: SGLT2i are diuretics, but not like any other diuretics
1
38
116
check out the awesome schematic from
@drlovygaur
about the trials and tribulations in DM nephropathy
#NephJC
8
69
118
Announcing the NSMC Internship Class of 2020
31
30
115
Who's ready for tomorrow? We're tackling the ISPD 2022 Peritonitis Guidelines!
Check out the VAs by
@Momen_Abbasi
+
@drpriyajohn
and the Summary by
@NephroSeeker
and
@Husamjz
#NephJC
3
66
107
See this table for all the major trials in a single pic from
@dilushiwijay
and
@priti899
#NephJC
#NephJC
1
43
104
The Top Nephrology Stories of 2022
0
72
101
10 Steps to Read a Paper
0
58
100
The Top Nephrology Stories of 2018
1
82
100
If you only read one
#TenTweetNephJC
this year, make it this one.
EMPA-KIDNEY is one of those landmark trials it is worth knowing inside-out, but you can still rapidly catch up on the key findings & author tweetchat secrets in the thread below👇
2
38
93
You might also find this useful table by
@sophia_kidney
helpful to keep track of the other trials we'll be referencing.
#nephjc
6
53
92
EMPA-Kidney: ‘Empa’sizing the role of Flozins in Chronic Kidney Disease
1
37
91
Welcome to
#TenTweetNephJC
✳️ Catch the key points, in 10 tweets ✳️
Up first - has an antibody that induces Minimal Change Disease finally been found?
2
37
90
The SGLT2i Crescendo with CREDENCE
4
41
90
#NephJC
has transformed to complete coverage for all things
#COVID19
#CoronaKidney
🦠
✔️ ACEi/ARB HTN
✔️ Transplant
✔️ Peds
✔️ Dialysis/CKD
✔️ AKI
4
47
90
T0i:
#NephJC
Glomerular endotheliosis= pathognomonic for PE
⚔️ Flt-1 inhibits VEGF
🔴Glom endotheliosis- swollen, vacuolated endothelial cells, swollen mesangial cells, subendothelial prot deposits+ tubular casts
Infographic by
@Nephroseeker
#Kireports
3
30
89
3
70
85
Hot Topic Alert: To Treat or Not to Treat: Bacteriuria in Kidney Transplant Recipients
5
28
81
DAPA-CKD: the visual abstract
DAPA-CKD: the visual abstract — NephJC
Superb visual abstract from Denisse Arellano !
www.nephjc.com
2
30
85
The
#NephJC
team has put together some resources for
#COVID19
from the kidney perspective here
We will keep updating it live
Keep checking back and share widely
#CoronaKidney
5
58
83
SGLT2 inhibitors: Mechanism
0
33
79
The 2021 KDIGO GN Guidelines
0
35
80
According to the American Society of Apheresis Guideline, AAV is a category II indication for PLEX (BUT not every AAV requires PLEX)
*RPGN (Cr ≥ 5.7 mg/dl) or,
*diffuse pulmonary hemorrhage.
Other AAV parameters fall into category III (below myeloma!). Do you agree??
#NephJC
5
37
79
So in summary, kidney pathology in COVID19 includes: ATI/ATN, glomerular ischemia/endothelial injury, virions, peritubular capillary congestion and/or fibrin thrombi, and collapsing glomerulopathy - possibly an exacerbation of APOL1 nephropathy.
#NephJC
4
30
77
Did you miss some of the nephrology literature in 2022?
Do you love rhyming couplets?
Then read our end of year round-up of the 23 most important papers in one thread!
(in the order all were covered by
#NephJC
, with links to the super-rapid
#TenTweetNephJC
trial catch-ups)
👇
2
32
74
perPLEXed by ANCA? Let PEXIVAS show you the path to less steroids and the end of plasma exchange
2
37
75
T0k: Since we are on this topic, how do you quantify congestion? Is seeing edema, or pulmonary asculation enough?
👇Look, here is a comprehensive approach
@escardio
@WilfriedMullens
@PieterMartensMD
@kevin_damman
#NephJC
3
30
73
T0c: Acetaminophen has 2 mechanisms for analgesic & antipyretic effects:
- By inhibiting the same COX, prostaglandin H2synthase. Different from NSAIDs, it blocks the enzyme at its peroxidase catalytic site.
- By interacting with cerebral endogenous cannabinoid receptors
#NephJC
4
18
72
T0b: Here’s our updated post on Landmark Trials in IgAN. Look at the topnotch chronology pod 2
#AQP2
made for IgAN 🤩
@NSMCinternship
@landmark_neph
#NephJC
1
35
74
Albuminuria = Proteinuria, Sorta?
0
31
71
The LUST Trial in Hemodialysis: Can Lung Ultrasound Guide Decongestive Therapy?
4
36
71
Time to Stop Starting RRT Early in AKI
0
36
72
T0e: Pathophysiology of pre-eclampsia
⚖️Central event is imbalance between angiogenic and antiangiogenic factors
#NephJC
👇The overview of pre-eclampsia pathogenesis from
@ASNKidney360
✍️By
@divyaa24
@silvishah
@NephroSeeker
@DrSandiDumanski
🔗
5
27
71
Terlipressin and Hepatorenal Syndrome: Winning the Battle and Losing the War?
0
26
69
The Coronavirus Conundrum: ACE2 and Hypertension Edition
2
40
67
T0j:
🧂 2013 US guidelines recommend <8 mEq/l for high risk pts and 10-12 mEq/l for normal risk/chronic hypoNa
🧂2014 European guidelines strictly recommend <10 mEq/l/24h correction rate in moderate, symptomatic hypoNa patients
✨Infographic by
@Nephroseeker
#NephJC
3
33
70
as we come to the end of the year, let's do a quick recap of the year in review for
#NephJC
We discussed 24 topics in 2021, including
14 RCTs
6 observational studies
3 guidelines
1 book club
2
24
69
Introducing Kidney Medicine NephJC Editorials
4
24
66
Announcing the NSMC Internship Class of 2019
1
24
68
Atrial Fibrillation, Anticoagulation and Dialysis: Do We Finally Have A Better Option?
5
41
66
The Top Nephrology Stories of 2021
#TopNephrology
@Nephro_Sparks
@krithicism
priti899
@drM_sudha
@M_Elraggal
@kidney_boy
@hswapnil
@rheault_m
1
39
66
💥 Treating Diuretic Resistance 💥
✅ Changing the route administration (IV vs oral)
✅ Albumin infusions
✅ Improve kidney perfusion
✅Sequential Nephron Blockade to Prevent Distal Sodium Reabsorption
#NephJC
#NephMadness
6
19
66
Fast or slow? How fast is fast in correcting hyponatremia?
Will a few sodium mEq/l make a difference in grand scheme of central myelinolysis or will it change the unbeatable mortal human condition?
👇Next
#NephJC
@NEJMEvidence
🧂Season ur arguments!
2
35
66
T0e: Taking this further, here is a great figure from in
@AJKDOnline
showing urine sediment and biomarkers based on different sites of nephron injury
#NephJC
3
21
64
#NephJC
Let’s get the fire started! Less than 1 hour ....
And a fascinating question for nephrologists: which one are you?
H/T
@torra_roser
, photo taken during
@ERAkidney
‘22 congress
4
23
65
Many nephrologists make decisions about which anticoagulant (if any) to recommend for atrial fibrillation in patients on haemodialysis on a weekly basis.
And we finally have more randomised data!
Enjoy a rapid catch-up with
#TenTweetNephJC
1
28
66
Re-TESTING Steroids for IgA Nephropathy
0
31
64
BEATing Calciphylaxis 👉a comprehensive summary by
@manasib33
, explaining what adaptative platform trials mean and how they can bring hope even to the darkest maladies in nephrology: calciphylaxis
Join
#Nephtrials
@ISNkidneycare
⏰ Nov 21, 9pm EST
2
29
64
T0e: Check out the summary of prior trials of ET-A antagonists in proteinuric renal diseases! And a bit of preview of today’s talk
#NephJC
🌈 infographic by
@DrPallaviPrasad
and
@Nephroseeker
4
30
62
T0c: C3G is subclassified in: C3GN and DDD.
Both share many overlapping features making it a diagnostic challenge.
Check out this nice overview❗️
#NephJC
🖼️ by
@AnvithaRangan
6
23
66
🤩Look at the beautiful
#visualabstract
on
@NEJM
trial DUPLEX, made by
@DrPallaviPrasad
Join
#NephJC
chats:
📆Nov 28th, 9 pm EST
📆Nov 29th, 9 pm EST
It will be fun and will learn a lot! 🪩🎉
0
24
63
Applications for the 2019 NSMC social media internship are closed.
We are really appreciative of the interest. This year 114 people applied, up 75% year over year.
1
14
62
The first NephJC Podcast is all about the NSAIDs in the Army study
5
25
62
COVID in the Kidney: An Autopsy Series
0
36
60
One Guideline for all CKD: BP Target 120
1
31
61
COVID and the Kidney Transplant Patient
3
42
60
NephJC Statement on Anti-Racism
0
25
60
T0b: What do we know so far about steroids in treating IgAN?
The
@landmark_neph
has a visual overview &
#NephJC
has recently discussed TESTING 2.0 👉
Beautifully updated
#IgAN
Trials infographic from
@divyaa24
👇
1
27
54
4
18
56
2021 KDIGO Updates for Glomerular Disease: The Visual Abstract
0
23
54
The SMART & SALT-ED Visual Abstract
0
33
55
Rituximab, Remission, & Relapses in ANCA-associated Vasculitis
This week we will discuss the resounding triumph of rituximab in maintenance therapy for ANCA-associated vasculitis.
🪦RIP Azathioprine?
👏 Summary by
@Myasirbaloch
&
@Nihal_Hamary
#NephJC
2
17
53
Tonight, we are rehashing the fluid war between balanced crystalloid vs saline in critically ill patients.
The link to the paper: ).
And here is the brilliant summary and VA by
@hellokidneyMD
.
#NephJC
3
13
53
T3d: There are few risk scores described in AAV, nephrologist can use:
- Berden classification: % crescents
- Mayo clinic: glomerular and tubulointerstitial involvement
- Brix score: histopath & GFR at diagnosis
Do you use any in your practice? When?
#NephJC
4
24
53
Immunoglobulin G4 (
#IgG4
)-related disease is a true chameleon with multisystem involvement.
Most common manifestation of IgG4-related disease in the kidneys is tubulointerstitial nephritis
#TIN
.
#NephJC
#NephMadness
@edgarvlermamd
1
17
53