Danny JJ Wang
@loft_lab
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Professor of Neurology and Radiology @USC, Director of LOFT lab
Los Angeles
Joined January 2023
Focused ultrasound with microbubbles can safely open BBB and the effect can be detected using DP pCASL MRI without contrast agent. Checkout the video and our preprint
biorxiv.org
This study applied diffusion-prepared pseudo-continuous arterial spin labeling (DP-pCASL) to quantify cerebral blood flow (CBF), arterial transit time (ATT), and blood-brain barrier (BBB) water...
📽️ New week, new animation with data from @loft_lab!. Focused ultrasound with microbubbles can temporarily open the blood-brain barrier, enabling noninvasive, targeted drug delivery while minimizing risk 🧠. Stay tuned for something big coming out of @loft_lab 👀
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Focused ultrasound induced BBB opening in the Dorsal Striatum of Non-Human Primates can be detected by BBB water exchange imaging using DP pCASL
biorxiv.org
This study applied diffusion-prepared pseudo-continuous arterial spin labeling (DP-pCASL) to quantify cerebral blood flow (CBF), arterial transit time (ATT), and blood-brain barrier (BBB) water...
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RT @NewsfromScience: The National Institutes of Health’s budget, and structure, would be preserved under a Senate bill for the 2026 fiscal….
science.org
Republicans on spending committee push back against proposed reorganization and overhead cuts
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Honored to attend SMART Africa MRI workshop focusing on ASL in Lagos Nigeria 🇳🇬 impressed by the growth and passion of MRI in Africa, glad to share ASL experience and contribute to global MRI, congrats to @SMARTA_NETWORK
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The 3rd annual meeting of 7T Translational Alliance of North America (7TANA) was successfully held at UTSW July 14-15 2025, great progresses in multiple frontiers of 7T clinical translations. Congrats to organizers Dr. Anke Henning and Sheeba Anteraper at UTSW see y'all next year
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ASL CBF changes with AD stages, indicating the value of ASL for detecting and monitoring AD progression.
🌟 New week, new animation 🧠.Research by our @loft_lab uses noninvasive ASL MRI to show that brain blood flow decreases even in the earliest stages of Alzheimer’s — before memory problems appear. This could help doctors catch the disease earlier and track treatment over time.
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Glymphatic dysfunction in Alzheimer’s disease: A critical appraisal | Science
science.org
Thirteen years after the initial publication defining the glymphatic system, we critically reappraise the role of its dysfunction in Alzheimer’s disease (AD). Our understanding of glymphatic function...
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Thanks for @audreypfan invite to visit UC Davis BME and imaging research center, impressive program great exchange with faculty and students, beautiful campus with an arboretum also thx @ydavidzhu
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Nice to attend #ASNR2025 ultrahigh field MRI in clinical neuroradiology session with @EMiddlebrooksMD @CanOzutemiz Dr Mai-Lan Ho and @PaechDC
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RT @NeuroscienceNew: Alzheimer’s Disrupts the Whole Body, Not Just the Brain. New research shows that Alzheimer’s disease impacts not only….
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Congrats to class 2025 of ISMRM junior and senior fellows, gold medalists especially to my mentor Dr Detre for winning gold medal 🥇 well deserved for career achievement
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RT @Wilcock_v2: Thank you @60Minutes for giving the devastating NIH pauses and proposed budget cuts the attention they deserve. ALL America….
cbsnews.com
Former National Institutes of Health Director Dr. Francis Collins, who abruptly left his NIH research lab in February, fears aggressive downsizing could impact Americans’ health.
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RT @NIH: Today, NIH announced a new initiative to expand innovative, human-based science while reducing the use of animals in research. Thi….
nih.gov
New initiative aims to reduce use of animals in NIH-funded research.
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Projected Lifetime Cancer Risks From Current Computed Tomography Imaging
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glad to join SMART MRI workshop to promote MRI and ASL in Africa.
The world of MRI science is evolving, and YOU can be a part of this exciting future! Join the 4th SMART Africa MRI Workshop in Lagos, July 23-25, 2025. Register by June 15, 2025!. Click the link below to register.
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RT @USCLONI: White matter tracts in the human brain by our medical animator Jim Stanis with data from our work on the @HumanConnectome Proj….
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