Linea Katharina Muhsal
@lineamuhsal
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Experimental ecology and evolution | multicellularity | evolution of cooperation | medical microbiology | microscopy
Osnabrรผck, Germany
Joined June 2020
RT @phylogenomics: Reading: . How a Biofilmโs Strange Shape Emerges From Cellular Geometry via @QuantaMagazine.
quantamagazine.org
Micro decisions can have macro consequences. A soft matter physicist reveals how interactions within simple cellular collectives can lead to emergent physical traits.
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RT @StelkensLab: Just out in PNAS! "The evolution of thermal performance curves in response to rising temperatureโฆ.
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A massive thank you to everyone involved @a_hamprecht, @CimenCansu, Janko Sattler, Lisa Theis, Oliver Nolte, @laurent_dortet, Rรฉmy Bonnin, Adrian Egli.
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The result is CarbaDetector, a free-to-use web-app for predicting the presence of carbapenemases in ๐๐ฏ๐ต๐ฆ๐ณ๐ฐ๐ฃ๐ข๐ค๐ต๐ฆ๐ณ๐ข๐ญ๐ฆ๐ด. Try it here: and let us know what you think or read the pre-print for more details.
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Using a dataset of 385 isolates and inhibition zone measurements for 8 antibiotics, we developed a machine-learning model to detect the presence of carbapenemases with high sensitivity and high specificity. This model was validated using 2 external datasets.
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such as ๐. ๐ฑ๐ฏ๐ฆ๐ถ๐ฎ๐ฐ๐ฏ๐ช๐ข๐ฆ and ๐. ๐ฎ๐ช๐ณ๐ข๐ฃ๐ช๐ญ๐ช๐ด are recognized as critical threats by the WHO. Detection of carbapenemases can be costly and/or requires a lot of workforce. Existing screening algorithms are often very sensitive, but show little specificity.
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Carbapenems are last-resort antibiotics used to treat infections with multidrug-resistant pathogens. Unfortunately, carbapenem-resistant pathogens are on the rise and pose a dangerous threat to global health. Specifically carbapenem-resistant ๐๐ฏ๐ต๐ฆ๐ณ๐ฐ๐ฃ๐ข๐ค๐ต๐ฆ๐ณ๐ข๐ญ๐ฆ๐ด,.
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Introducing CarbaDetector: A web-app to predict the presence of carbapenemases in ๐๐ฏ๐ต๐ฆ๐ณ๐ฐ๐ฃ๐ข๐ค๐ต๐ฆ๐ณ๐ข๐ญ๐ฆ๐ด based on disk diffusion tests. Check out the preprint here: . or read this thread for more info.
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RT @mdancho84: Understanding probability is essential in data science. In 4 minutes, I'll demolish your confusion. Let's go! https://t.cโฆ.
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RT @a_hamprecht: Neue Stelle als Postdoc (E13) am Institut fรผr medizinische Mikrobiologie und Virologie im schรถnen Oldenburg. Spannende Foโฆ.
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RT @iamsamayp: New paper alert!!๐๐ฅ๐๐.Survival of the resistant: When Myxococcus xanthus dies, antibiotic-resistant microbes rise, even withโฆ.
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RT @PRX_Life: Weโre accepting submissions for our new Collection on Adaption and Learning in Biological. If you study living systems with aโฆ.
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RT @MarcoMauri81: ๐จ Next Friday 21/02 at 15:30 EU time, Rinke van Tatenhove-Pel @RJvTatenhovePel (TU Delft) will present the talk. Populatiโฆ.
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RT @theStockerLab: ๐ The Experimental #Microfluidic Course is back @ETH!๐ . Join us to explore the fundamentals of microfluidic technologโฆ.
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After a productive, educational, and fun year as a PostDoc with @a_hamprecht working on medical microbiology, I am now back in the lab of @KostChristian to teach and investigate microbial ecology and evolution.
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RT @a_hamprecht: Heute in der Oldenburger Innenstadt im Pop-Up Store der Uni Oldenburg- wir informieren รผber Antibiotikaresistenz und unserโฆ.
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RT @barisch_c: ๐ฅ Exciting! First research article from the lab SUBMITTED! Time for celebrations ๐๐พ
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RT @HerwigBachmann: Do you think it is possible to train parasitic wasps to identify the microbes best suited to ferment plant-based substrโฆ.
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