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leslie sheppard Profile
leslie sheppard

@leslieasheppard

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692
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AI Advisor Board Member World AiQ @MITDLab1 @MIT Alum AI Data Science Lab, Founder @MITRiskGroup Entrepreneur, SystemsEngineer [email protected]

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Joined April 2009
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@leslieasheppard
leslie sheppard
1 month
Materials Science + AI 🚀 “engineers can now predict and design materials across multiple scales – from the atomic blueprint up to real-world products – before they ever set foot in a factory. 🚨This approach, known as predictive multiscale materials design, merges
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@karpathy
Andrej Karpathy
8 hours
I packaged up the "autoresearch" project into a new self-contained minimal repo if people would like to play over the weekend. It's basically nanochat LLM training core stripped down to a single-GPU, one file version of ~630 lines of code, then: - the human iterates on the
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@james_y_zou
James Zou
2 days
We created AI agents based on scientists' personas (eg Einstein, Feynman) and built a Kaggle-like platform for them to freely post ideas, compete and collaborate. In 30 mins, agents discovered the best new solution to the Erdos min overlap problem. Great job by @federicobianchy
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@leslieasheppard
leslie sheppard
4 hours
Jevon’s Paradox: 🚀🚀 “It mathematically proves that as the unit cost of digital intelligence and coding drops, the aggregate demand for complex AI agents and the infrastructure to support them surges exponentially, creating a massive new downstream ecosystem that requires human
@rohanpaul_ai
Rohan Paul
22 hours
Brilliant economic paper directly models the "Structural Jevons Paradox" happening right now in the AI industry. The cost of running an LLM is dropping, but total computing energy is exploding anyway. It mathematically proves that as the unit cost of digital intelligence and
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@pmarca
Marc Andreessen 🇺🇸
22 hours
💯
@Dan_Jeffries1
Daniel Jeffries
2 days
The jobs apocalypse is the Population Bomb of our time. Instead we're seeing more hiring in the job most affected by AI: programming. That should have been clear and obvious to anyone with basic economics understanding and good handle on the history of technology but it's sadly
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@a16z
a16z
11 hours
"Not having a coding experience is becoming an advantage." Replit CEO Amjad Masad: "You don't need any development experience. You need grit. You need to be a fast learner." "If you're a good gamer, if you can jump in a game and figure it out really quickly, you're really good
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@aakashgupta
Aakash Gupta
9 hours
We’re spending $200B+ a year on data centers to power AI. One company raised $11M, grew human brain cells on a chip, and the cells taught themselves to play a 3D shooter in a week. Cortical Labs grew 200,000 human neurons on a silicon chip and taught them to play Doom. The cells
@MAstronomers
Curiosity
13 hours
🚨: A petri dish of human brain cells just learned to play DOOM
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@Citrini7
Citrini
8 hours
I originally published this financial history article in January 2023, but its core point about how markets have a habit of treating geopolitical risk as background noise right up until the moment it’s not seems relevant again. https://t.co/KjyIjzqpnb
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citriniresearch.com
A hundred years, ain't a damn thing changed.
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@JulienBek
Julien Bek
2 days
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@ArtificialAnlys
Artificial Analysis
1 day
AI is progressing rapidly: GPT-5.4 Pro (xhigh) has achieved a massive 10 point gain in CritPt, a benchmark where the highest score was only 9% in Nov ‘25 This is the largest incremental gain we have seen from a single release. CritPt is a benchmark with a private dataset that
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@forallcurious
All day Astronomy
2 days
🚨: Scientists have discovered hidden geometric structures inside matter that govern the fundamental rules of reality
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@jukan05
Jukan
2 days
Just in: Samsung, after raising NAND prices by 100% in the first quarter, is now planning another 100% NAND price increase in the second quarter. $SNDK
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@Variety
Variety
2 days
Netflix has acquired interpositive, a start-up founded by Ben Affleck that makes AI-powered tools for filmmakers. • The system builds AI models from a film’s dailies to assist with postproduction tasks like color, relighting and VFX while keeping filmmakers “at the center of
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@bearlyai
Bearly AI
2 days
Founder of Chicago-based prop trading firm DRW says compute will be world's top commodity in 10 years. People will spend more on GPUs than an oil, which means that there should be a futures financial market for GPUs.  Interesting implications for startups and cloud providers:
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@damianplayer
Damian Player
2 days
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@leslieasheppard
leslie sheppard
2 days
5.4 🚀
@IterIntellectus
vittorio
2 days
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@OpenAI
OpenAI
2 days
GPT-5.4 Thinking and GPT-5.4 Pro are rolling out now in ChatGPT. GPT-5.4 is also now available in the API and Codex. GPT-5.4 brings our advances in reasoning, coding, and agentic workflows into one frontier model.
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@demishassabis
Demis Hassabis
3 days
Still super underrated what the incredible @NotebookLM can do. It's magical - one of my favourite AI tools.
@NotebookLM
NotebookLM
3 days
Introducing Cinematic Video Overviews, the next evolution of the NotebookLM Studio. Unlike standard templates, these are powered by a novel combination of our most advanced models to create bespoke, immersive videos from your sources. Rolling out now for Ultra users in English!
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@MIT
Massachusetts Institute of Technology (MIT)
3 days
Over 10,000 Americans are waiting for a liver transplant. MIT Engineers developed injectable “mini livers” that could take over the functions of a failing liver. The technology could offer an alternative to transplantation or provide support until a donor organ is available.
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@MIT
Massachusetts Institute of Technology (MIT)
3 days
A team of MIT engineers wondered: Could an expert’s unconscious know-how be accessed, and even taught, to quickly bring a novice up to an expert’s level? The answer appears to be “yes,” at least for a particular type of visual-learning task.
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news.mit.edu
Patterns of gaze and attention can reveal how some people unconsciously figure out how to master a task, MIT researchers have shown.
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@ProfBuehlerMIT
Markus J. Buehler
22 days
Gave Gemini 3 Deep Think an image of a 3D spider web and asked for an interactive design tool. It generated a full design suite (procedural control, simulation, optimization) with STL export capability. I used it to engineer new metamaterials and a spider-web inspired bridge
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