Laura Medlock, PhD
@laurmedlock
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Postdoc Fellow at @UHN & Krembil Brain Institute with @stressynomics. Computational neuroscience, neural coding, and pain/stress. 🧠🧑💻 they/them.
University of Toronto, Canada
Joined March 2017
RT @PrescottLab: Our latest work uses @RAMalgoTheRobot to investigate the role of different somatosensory afferents in pain sensitivity 💢.
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Out now in @SfNJournals! 👋 Our latest work on touch and vibration sensing in rodent mechanoreceptors. A beautiful experimental and modelling collaboration thanks to Dhekra Al-Basha, @Chris_Dedek, @AHalawa99 and the whole @PrescottLab team.
www.jneurosci.org
Somatosensory coding in rodents has been mostly studied in the whisker system and hairy skin, whereas the function of low-threshold mechanoreceptors (LTMRs) in the rodent glabrous skin has received...
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RT @PrescottLab: Interested in Na+ channels and pain? . Come talk to Stephanie at #SfN2024 about our recent work showing that different Nav….
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I’m at #SfN2024 presenting my latest work on spinal receptive fields and pain. We show that spatially and temporally disorganized stimuli preferentially activates inhibition! . Come chat about the implications for therapeutic neuromodulation on Sunday from 1-5pm at 112.01 🤩
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Thanks @CEEA_ACEG for the opportunity to share the USRP program at @UofTEngineering. A bigger thanks to @KilkennyDawn for letting me be a part of this awesome program. 🎉.
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On route to @CEEA_ACEG in Edmonton! ✈️🏔️ I will be giving a talk on my latest work with @KilkennyDawn at @UofTEngineering on our development of USRP – a support program for Undergraduate Engineers doing summer research at @UofT. #CEEA2024
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RT @PrescottLab: That’s a wrap on #CAN2024! Thanks everyone for stopping by our posters and for the great feedback 👋 @CAN_ACN
https://t.co/….
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I’m presenting on spatiotemporal processing and spinal receptive fields tomorrow at #CAN2024 🔘. Stop by P3-D-439 for a lil’ neural coding!
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RT @RAMalgoTheRobot: This just in: There are better ways to perform nociceptive behaviour tests! Read the latest @_TheTransmitter article h….
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RT @VAbraira: 🔬 Check out our study on glycinergic interneurons in the mouse spinal cord, revealing their key role in controlling motor per….
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Out now in @NeuroCellPress 👏 Such a pleasure to be included by @SpinalCordMark and @VAbraira on this project.
Excited to be part of this incredible work by @SpinalCordMark and @VAbraira, out now in @NeuroCellPress! 🎉. In this work, @laurmedlock uses a network model to show how PV+ inhibitory neurons in the deep dorsal horn gate cutaneous-evoked muscle activity.
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RT @PrescottLab: Check out this great summary of our latest work in @NeuroCellPress on high-frequency #SpinalCordStimulation. ⚡️ Thanks @MC….
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This #heterogeneity in RA tuning suggests that co-activation patterns play a greater role in #populationcoding in rodents than other dichotomously tuned species. 🐁 (4/4)
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To explore this spectrum we built models of LTMRs. They showed that the integration window of different RAs transitions from wide ➡️ narrow as frequency preference moves from low ➡️ high frequencies. (3/4)
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⚡️ We found that unlike the dichotomous frequency preference of RAI and RAII afferents in other species (e.g. primates), rodent RAs form a continuum of frequency preferences. (2/4)
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Our latest #preprint on touch encoding in rodent mechanoreceptors is out now! 👈. 🔗 Many thanks to the huge, collaborative effort from the @PrescottLab that spans (most of) my PhD! 🥳(@Chris_Dedek @AHalawa99 @SickKidsNews @bme_uoft) (1/4).
www.biorxiv.org
Somatosensory coding in rodents has been mostly studied in the whisker system and hairy skin, whereas the function of low-threshold mechanoreceptors (LTMRs) in rodent glabrous skin has received scant...
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RT @nschawor: updated for 2024: list of summer schools & short courses in the realm of (computational) neuroscience or data analysis of EEG….
docs.google.com
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RT @PrescottLab: 20 years ago, Chesler et al. showed that the greatest source of variability in evoked pain responses was the experimenter.….
www.cell.com
Preclinical pain testing traditionally utilizes techniques—such as stimulating by hand and measuring responses by eye—that limit reproducibility. Dedek et al. describe a device for consistent...
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Our latest #SpinalCordStimulation work from the @PrescottLab is out now in @NeuroCellPress 🥳. Incredible work by @Sagalajev_B and the whole team! I was happy to be included in such a collaborative (and long-anticipated!) project.
Five years in the making and our #SpinalCordStimulation work by @Sagalajev_B and amazing collaborators is finally published @NeuroCellPress! 🤩. Read it here: #PainResearchForum #Pain #ChronicPain #Neuromodulation
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