https://t.co/A0zacCAkbj

We are thrilled to announce that Infinity Bio has closed our Series A investment, led by the amazing team at Illumina Ventures. As part of the deal, Infinity Bio has acquired Serimmune Inc, a complementary antibody reactome service provider. This event marks a major milestone

𝗖𝗼𝗵𝗼𝗿𝘁 𝘀𝘁𝘂𝗱𝘆 𝗼𝗳 𝘁𝗵𝗲 𝘄𝗲𝗲𝗸 - The article “𝘋𝘪𝘴𝘦𝘢𝘴𝘦 𝘥𝘪𝘢𝘨𝘯𝘰𝘴𝘵𝘪𝘤𝘴 𝘶𝘴𝘪𝘯𝘨 𝘮𝘢𝘤𝘩𝘪𝘯𝘦 𝘭𝘦𝘢𝘳𝘯𝘪𝘯𝘨 𝘰𝘧 𝘉 𝘤𝘦𝘭𝘭 𝘢𝘯𝘥 𝘛 𝘤𝘦𝘭𝘭 𝘳𝘦𝘤𝘦𝘱𝘵𝘰𝘳 𝘴𝘦𝘲𝘶𝘦𝘯𝘤𝘦𝘴” published in @ScienceMagazine from corresponding authors Anshul

There is an incredible amount “under the hood” here, which we hope will accelerate discovery of novel venom-derived lead compounds. Congrats to all involved for bringing this important project to fruition!

This paper is the culmination of a herculean effort to enable peptide therapeutic discovery using M13 hyperphage, which involved the development of new library design principles, and new cell-based panning and NGS analysis workflows.

Thank you for highlighting our work @us_hupo ! We’re very grateful for this recognition, especially since the project was such a labor of love that spanned many years and collaborations – most notably with the amazing Martin Steinegger @thesteinegger .

Portal and Veranome are currently considering strategic opportunities to advance the LISH-LnR technology and the adjacent supporting assays. If interested in learning more, please reach out!

We also report a system of “molecular rheostats” for tuning LISH-LnR assay performance, a complementary LISH-seq assay for probe panel qualification, and a QC method to determine the quality and availability of fixed tissue RNA.

Portal developed the chemistry in partnership with Veranome Biosystems, which developed an incredible instrument and software. LISH-LnR (Ligation In Situ Hybridization Lock’n’Roll) detects the spatial location of mRNA molecules within fixed (including FFPE) tissue architectures.

We’re so excited to present LISH-LnR, a powerful spatial transcriptomic platform spawned in my lab at Johns Hopkins and then spun into a startup company called Portal Bioscience. https://t.co/ApNHyW9n4V

🎉 Congratulations to @KateGrabowski , PhD (Associate Professor of Pathology, Johns Hopkins School of Medicine Faculty) for winning the Apple Vision Pro raffle at our Open House! 🥳 Thank you to everyone who joined us to explore our innovative MIPSA technology and antibody

Last week, we hosted students and faculty from Coppin Academy High School. It was inspiring to see Baltimore's best and brightest experience hands-on STEM experiments and immunology learnings- the future looks bright! 💫 #STEM #Baltimore #Immunology #Reactome

@EricTopol Absolutely agree with @EricTopol ! 🙌 Characterizing the "immunome"—from lifetime viral exposures to autoantibody reactivities—provides critical insights into disease mechanisms and biomarker development. We are the leader in comprehensive antibody reactome profiling, and are

Calling local biomedical professionals! Please attend our open house to learn how your cohort study can benefit from antibody reactome profiling. You'll get to see our beautiful Baltimore lab and can enter to win a new Apple Vision Pro 🤯 Please RT to help spread the word!

Taking Pharokka output as input, Phold uses the ProstT5 protein language model to rapidly convert amino acid sequences to Foldseek 3Di structural tokens, & then searches these with Foldseek against a database of 1M+ phage protein structures folded with Colabfold (2/n)

A fantastic collaboration with @thesteinegger and very excited about future projects using this type of approach to discover novel peptide therapeutics. If you have ideas for applications or indications, please reach out to us!

Leveraging antibody profiling for advanced healthcare insights

New paper ( https://t.co/KdFeOoEKqp) in @AdvSciNews (Advanced Materials) describes novel biomaterial scaffold, the “artificial lymph node matrix,” to stimulate production of antigen-specific T immune cells. @Natalie_K_L @HopkinsMedicine @JHUPath @JHUBME @JHUMaterials @TTECJHU

If you do epi or work on a cohort study, you’ve probably captured nature (genetics 🧬) --- now it’s time to capture nurture (exposures and infections 🦠), through the lens of the immune system! Please reach out to jp.laine@infinitybio.com for more info!

Check us out at https://t.co/gwS3LxcZ3Q. We have a state-of-the art purpose-built lab in Baltimore, MD, USA. Our quality assurance system and management team ensure that your samples and data are tracked safely and securely throughout the entire process.