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Krauthammer Lab Profile
Krauthammer Lab

@krauthammerlab

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361

Clinical and translational informatics news from the lab of Michael Krauthammer | @UZH_en and @Unispital_USZ Ran by KLab members πŸ‘©β€πŸ’»πŸ‘¨β€πŸ’»

Joined April 2013
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@krauthammerlab
Krauthammer Lab
1 year
Our latest study "Machine learning prediction of prime editing efficiency across diverse chromatin contexts" is out @NatureBiotech! Shout out to our awesome collaborators @nicopmat @schwanklab @bvansteensellab and all (co)-authors πŸ‘ https://t.co/G5C7CgpSQ5 @UZH_Science @DQBM_uzh
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nature.com
Nature Biotechnology - A machine learning model for prime editing efficiency prediction takes into account chromatin context.
@nicopmat
Nicolas Mathis
1 year
Our paper exploring the effect of chromatin on prime editing and diverse pegRNA designs was published today! πŸ‘¨β€πŸ’»πŸ§¬πŸŽ‰ https://t.co/hoygYAHbPH https://t.co/xvSlhTJvNV @UZH_Science @NatureBiotech @schwanklab @krauthammerlab @bvansteensellab 🧡
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@krauthammerlab
Krauthammer Lab
10 months
Our preprint "TAMER: A Test-Time Adaptive MoE-Driven Framework for EHR Representation Learning" is out! A great work by @yhzhu99 @XiaochenZheng3 πŸ‘ Paper: https://t.co/8MDD76pJ4a #MachineLearning #Healthcare @UZH_en @DQBM_uzh
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@farhadnz
Farhad Nooralahzadeh, PhD
11 months
πŸš€ Wrapping up 2024 with a bang! Check out our exciting ArXiv paper: "Explainable Multi-Modal Data Exploration in Natural Language via LLM Agent." 🌟 AI just got smarter and more accessible. Here's to 2025! πŸŽ‰ #Multimodality #AgenticAI #ExplainableAI #LLMs https://t.co/RIjiWLHIhB
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arxiv.org
International enterprises, organizations, or hospitals collect large amounts of multi-modal data stored in databases, text documents, images, and videos. While there has been recent progress in...
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@krauthammerlab
Krauthammer Lab
10 months
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@krauthammerlab
Krauthammer Lab
10 months
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@krauthammerlab
Krauthammer Lab
10 months
π—˜π˜…π—°π—Άπ˜π—Άπ—»π—΄ 𝗣𝗡𝗗 π—’π—½π—½π—Όπ—Ώπ˜π˜‚π—»π—Άπ˜π˜† 𝗢𝗻 π—”π—œ 𝗳𝗼𝗿 π—£π—Ώπ—²π—°π—Άπ˜€π—Άπ—Όπ—» π—’π—»π—°π—Όπ—Ήπ—Όπ—΄π˜† in Our Lab! Candidate will work on AI-driven precision oncology, developing solutions that could revolutionize how we approach cancer treatment. Apply πŸ‘‰ https://t.co/Oo7hSW62vF
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@farhadnz
Farhad Nooralahzadeh, PhD
1 year
I am hiring a PhD student to join our team at the Medical Informatics at UZH and work on an exciting SNSF project starting early next year. SNF PhD position in Medical NLP Please share πŸ‘πŸ™Œ... https://t.co/zh1DIfYS3n #uzh, #krauthammerlab
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@krauthammerlab
Krauthammer Lab
1 year
πŸ’«We are hiring a PhD student to join us and work on an exciting SNSF project starting early next year. "SNF PhD position in Medical Informatics with a Focus on Natural Language Processing" Please share πŸ™Œ https://t.co/7DAJP9XcK6 @farhadnz
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@Amina_mollaysa
Amina Mollaysa
1 year
Bridging genome editing, protein engineering, and applied machine learning in biology: Great to see our latest study, spearheaded by @marquark, out in @naturemethods. Check out the paper! πŸ§¬πŸ“· https://t.co/hANtAKwFEm @nicopmat @schwanklab @krauthammerlab
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nature.com
Nature Methods - This work introduces engineered TnpBmax proteins with enhanced efficiency and an expanded targeting range. By leveraging an extensive dataset on editing efficiencies, it also...
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@naturemethods
Nature Methods
1 year
And read the Research Briefing on the work here: https://t.co/tfT2FyOl8a
@naturemethods
Nature Methods
1 year
.@schwanklab and colleagues describe TnpB variants with increased activity and a broader targeting range, along with a deep learning model to predict Ο‰RNA efficiency. @marquark @nicopmat @Amina_mollaysa @krauthammerlab https://t.co/lakYFNn3ot
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@naturemethods
Nature Methods
1 year
.@schwanklab and colleagues describe TnpB variants with increased activity and a broader targeting range, along with a deep learning model to predict Ο‰RNA efficiency. @marquark @nicopmat @Amina_mollaysa @krauthammerlab https://t.co/lakYFNn3ot
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@marquark
Kim Fabiano Marquart
1 year
If you're more of a visual learner, this explainer video is for you πŸ™Œ
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@marquark
Kim Fabiano Marquart
1 year
Our TnpB story has been published in @naturemethods πŸš€ Check out the thread by @schwanklab to dive right in.
@schwanklab
Gerald Schwank
1 year
Excited to share our latest study! Today in @naturemethods the @schwanklab and @krauthammerlab report in @marquark et al. 'Effective genome editing with an enhanced ISDra2 TnpB system and deep learning-predicted Ο‰RNAs' (1/6) https://t.co/lqDc5Kn2Xw
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@UZH_en
University of Zurich
1 year
TnpB is much smaller than the well-known CRISPR-Cas "gene scissors". The tool for targeted modification of the genome has now been improved to such an extent that it could one day be used to treat a genetic defect that leads to a lifelong high cholesterol level.
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@UZH_ch
UniversitΓ€t ZΓΌrich
1 year
TnpB ist viel kleiner als die bekannte Β«GenschereΒ» CRISPR-Cas. Nun wurde das Tool zur gezielten VerΓ€nderung des Genoms so verbessert, dass es dereinst zur Behandlung eines Gendefekts eingesetzt werden kΓΆnnte, der zu einem lebenslang stark erhΓΆhten Cholesterinspiegel fΓΌhrt.
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@marquark
Kim Fabiano Marquart
1 year
Check the @naturemethods research briefing associated with our latest study on TnpB for effective genome editing https://t.co/zmIfUECkxo
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@krauthammerlab
Krauthammer Lab
1 year
Our latest collab with @schwanklab is out today! "Effective genome editing with an enhanced ISDra2 TnpB system and deep learning-predicted Ο‰RNAs" https://t.co/K5EfaMgOKB Congrats to all authors & collaborators!πŸ‘πŸŽ‰ @marquark @Amina_mollaysa @DQBM_uzh @Unispital_USZ @UZH_H2R
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nature.com
Nature Methods - This work introduces engineered TnpBmax proteins with enhanced efficiency and an expanded targeting range. By leveraging an extensive dataset on editing efficiencies, it also...
@schwanklab
Gerald Schwank
1 year
Excited to share our latest study! Today in @naturemethods the @schwanklab and @krauthammerlab report in @marquark et al. 'Effective genome editing with an enhanced ISDra2 TnpB system and deep learning-predicted Ο‰RNAs' (1/6) https://t.co/lqDc5Kn2Xw
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@nicopmat
Nicolas Mathis
1 year
Bridging genome editing, protein engineering, and applied machine learning in biology: Great to see our latest study, spearheaded by @marquark, out today in @naturemethods. Check out the paper! πŸ§¬πŸ’» @UZH_Science @schwanklab @krauthammerlab
Tweet card summary image
nature.com
Nature Methods - This work introduces engineered TnpBmax proteins with enhanced efficiency and an expanded targeting range. By leveraging an extensive dataset on editing efficiencies, it also...
@schwanklab
Gerald Schwank
1 year
Excited to share our latest study! Today in @naturemethods the @schwanklab and @krauthammerlab report in @marquark et al. 'Effective genome editing with an enhanced ISDra2 TnpB system and deep learning-predicted Ο‰RNAs' (1/6) https://t.co/lqDc5Kn2Xw
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@krauthammerlab
Krauthammer Lab
1 year
Our work "Rethinking Molecular Design: Integrating Latent Variable and Auto-Regressive Models for Enhanced Goal Directed Generation" got accepted at the ICML 2024 Workshop AccMLBio! Great work by Arthur-Louis Heath and @Amina_mollaysa πŸ‘πŸŽ‰! πŸ—žοΈ https://t.co/sIFGryCcfa
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@krauthammerlab
Krauthammer Lab
1 year
'Explainable deep learning for disease activity prediction in chronic inflammatory joint diseases' is now out in @PLOSDigiHealth @cecile_tt @CarolineOspelt πŸ‘πŸŽ‰ Paper:
@krauthammerlab
Krauthammer Lab
2 years
Our preprint "Explainable deep learning for disease activity prediction in chronic inflammatory joint diseases" is out! A great work by @cecile_tt and all collaborators @CarolineOspelt at @Unispital_USZ πŸ‘πŸŽ‰! Paper: https://t.co/CWiIURHPU1
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