Jun Yang
@Junjyang
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Pharmacologist and geneticist through and through
Tennessee, USA
Joined October 2009
This is HUGE! No embargo needed for @AACR publications deposited in PubMed Central - enabling compliance with the NIH public access policy without spending exorbitant open access fees.
You can read the AACR journals' policy here: https://t.co/mq2WsdK9Pd "The Author Accepted Manuscript is permitted to be deposited in PMC and made available to the public on or after the first online publication date of the Version of Record."
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New paper alert! Our team published in @NatureComms on MeiHMM - a hidden Markov model that identifies meiotic nondisjunction error types in chromosomal abnormalities, like Down Syndrome, without parental data! #ComputationalBiology @StJudeResearch
https://t.co/kQCen4lBns
nature.com
Nature Communications - The authors report a computational framework for determining the meiotic/mitotic origin of nondisjunction (NDJ) in trisomies without parental data. Applying this to Down...
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Kudos to @maud_maillard on her new paper in @jclinicalinvest! Our findings indicate NUDT5 is a key regulator of thiopurine metabolism, offering new insights into how cells strike the balance between de novo vs salvage purine synthesis.
Thiopurines for the treatment of cancer or autoimmune disease are limited by their toxicity. @MaudMaillard @Junjyang @StJudeResearch identify germline NUDT5 variants that affect thiopurine metabolism and cytotoxicity in children with ALL, having implications for individualized
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One of my favorite meetings!
We are a go! #ESHALL2025 started this morning! We are happy to welcome participants in Malahide for the 2,5-day ESH 4th Translational Research Conference on ALL More information➡ https://t.co/adas9FSZCP Chairs: @kathrinbernt @CoolsJn @DombretHerve @ullawk
#ESHCONFERENCES #LEUsm
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Instead of listing my publications, as the year draws to an end, I want to put pressure on the commonplace assumption that productivity must always increase. Good research is disruptive and thinking time is central to high quality scholarship and necessary for disruptive research
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Why is #ALL highly curable in #kids but carries a much worse prognosis in #adults?? Check out our new paper @JCO_ASCO describing genomics of age-related differences in ALL drug sensitivity @StJudeResearch @MDAndersonNews @UChicagoLeuk @NitinJainMD
Researchers identified distinct molecular subtypes of B-ALL that occur in different age groups explaining why cure rates vary between children and adults. The study suggests treatments should be tailored based on underlying molecular groups beyond age. https://t.co/bLphZdNkJA
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In beautiful #Madrid for #EHA2024 @EHA_Hematology rooting for Carolin and her poster presentation re inotuzumab resistance in B-ALL
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Congratulations to Ching-Hon Pui, MD, for receiving the @AACR-@StBalrdricks Foundation Award for Outstanding Achievement in Pediatric Cancer Research. Your pioneering research is lifesaving, and your commitment is inspiring. https://t.co/JNESB5PcJy
#AACR24
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The stars are aligning (literally) for our paper to come out today 😂🌞 @jiyang_yu @StJudeResearch
By characterizing B-cells’ developmental stages, St. Jude scientists designed and tested a drug combination to effectively treat resistant B-cell leukemia and reduce side effects. Learn more about the research by @Jiyang_Yu and @JunJYang.
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One of the highest honors and deeply grateful to all current and past trainees! And also gratitude to my own mentors, especially @mrelling
Congratulations to @JunJYang, PhD, the St. Jude Postdoctoral Association Mentor of the Year Award winner. In a rich pool of nominees, Yang stood out among his peers for his work as a mentor, sponsor and coach, guiding early career scientists and researchers to paths of success.
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Kudos to @maud_maillard for leading this important work, with colleagues around the world #Singapore #India #Guatemala @cyrineeliana @COGorg @getinvolvedchla @pgrnhub @mrelling
Happy to share our latest work on mercaptopurine tolerance in patients with both TPMT and NUDT15 variants published in @JNCI_Now. Many thanks to collaborators all around the world, amazing PI @Junjyang, and patients! @StJudeResearch @cpicpgx @pharmgkb
https://t.co/l2WLwAzN6w
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🧐 Assessment of survival outcomes and drug sensitivities across various definitions of hyperdiploidy in childhood #AcuteLymphblasticLeukemia ➡️ https://t.co/qd1iWfxqkO
#leusm #pedcsm @shawnleehr @Junjyang
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Amazing story of a Nigerian pharmacist who identified issues in her health center, went through the literature for solutions, discovered PGx on her own, joined @PGRN, identified mentors, obtained a grant, wrote a paper, and conducted a PGx study at her hospital to help her people
Tomorrow!
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Another PGRN member taking on a major leadership role, demonstrating the impact of pharmacogenomics in pharmacy education, research, and practice! Congrats Deanna. @pgrnhub
Welcome, Dean Deanna Kroetz!🎉 "I can’t wait to meet more of you in the coming days and weeks. Go Buckeyes!" Be sure to say hi to our new dean around the college! #OSURx #ohiostateuniversity #pharmacybuckeyes #firstday
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Excited for the @AllofUsResearch half-day workshop tomorrow at 2023 PGRN Annual Meeting #PGRN2023 #PGx
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