
Jacob Hooker
@jmhooker
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Chemist turned neuroscientist. @MGHMartinos @MGHImaging. Editor-in-chief of @ACSChemNeurosci.
Boston, MA
Joined November 2013
RT @Scott_LabUM: Our latest paper describes automated synthesis and preclinical imaging of a novel [18F]Fluorolidocaine analog via sequenti….
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RT @Eikonizo: @Eikonizo is excited to be in Philly for the @alzassociation #AAIC24. A great opportunity to learn from and meet with some of….
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RT @JohnOBrennan2: Wow. The Harris team are out of the blocks in lightening quick time with this superb ad.
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RT @ACSChemNeurosci: 📢Stay up to date with the latest📢 This new collection of #ACSChemNeuro research joins the discussion around #MDMA as a….
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RT @ACSChemNeurosci: 📢New collection of #ACSChemNeuro research as the FDA is expected to announce a decision on a new treatment involving #….
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RT @ACSChemNeurosci: FDA Advisory Committee votes against recommending Lykos' #MDMA treatment for PTSD. Read our latest MDMA research here….
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RT @jmhooker: @ACSChemNeurosci @zenbrainest Super interesting discussion about expectancy bias… check out
pubs.acs.org
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Overall, I thought the discussion was less focused on the tremendous unmet need. Maybe I’m a bit too cavalier, but I certainly felt the benefits outweigh the risks (with plenty of guardrail caveats).
@jmhooker @zenbrainest want to kick off the discussion?.
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RT @ACSChemNeurosci: Fascinating discussions online today surrounding the FDA's consideration of a new #MDMA treatment for PTSD 🤔. When is….
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RT @bsw5020: Today the world can watch a film that has been called “the best movie I have seen in 30 years.”. For Love & Life: No Ordinary….
amazon.com
A deeply moving documentary illustrating the transformative power of love, hope and activism. The film follows Brian Wallach and his wife Sandra after his ALS diagnosis at age 37. Anchored by a deep...
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RT @zenbrainest: Whoo hoo! Major paper now out in @science :."AlphaFold2 structures guide prospective ligand discovery".Collaboration with….
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RT @Nature: An orangutan in Sumatra surprised scientists when he was seen treating an open wound on his cheek with a poultice made from a m….
nature.com
Nature - The Sumatran orangutan used a plant known to humans for its medicinal qualities.
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Really excited to share the hard work of a killer team. This project was a long time in the making and hit the COVID shutdown timeline and “penalty” but the team saw it through and it’s really great science. @ACSCentSci
pubs.acs.org
Cyclooxygenase-2 (COX-2) is an enzyme that plays a pivotal role in peripheral inflammation and pain via the prostaglandin pathway. In the central nervous system (CNS), COX-2 is implicated in neurod...
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RT @MGHMartinos: Multidisciplinary team at @MGHMartinos @MGH_CNTR studied 30 active-duty U.S. Special Operations Forces: .
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RT @ComaRecoveryLab: Impact of Repeated Blast Exposure in Active-Duty U.S. Special Operations Forces: We thank the….
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RT @Nature: Nature research paper: Bitter taste receptor activation by cholesterol and an intracellular tastant
nature.com
Nature - Cryo-electron microscopy structures of the type 2 taste receptor TAS2R14 in complex with Ggust and Gi1 identify cholesterol as an orthosteric agonist and the bitter tastant cmpd28.1 as a...
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RT @zenbrainest: Wow!!.De novo design of drug-binding proteins with predictable binding energy and specificity | Science .
science.org
The de novo design of small molecule–binding proteins has seen exciting recent progress; however, high-affinity binding and tunable specificity typically require laborious screening and optimization...
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