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Jacob Hooker Profile
Jacob Hooker

@jmhooker

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Chemist turned neuroscientist. @MGHMartinos @MGHImaging. Editor-in-chief of @ACSChemNeurosci.

Boston, MA
Joined November 2013
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@Scott_LabUM
ScottLab
1 year
Our latest paper describes automated synthesis and preclinical imaging of a novel [18F]Fluorolidocaine analog via sequential C-H radiolabeling and is out in @rsc_medchem. Congrats @MadisonFrazier1 (1st paper!) @jays_wright @afallenbrooks. Read it here: https://t.co/9KTfc2r56Z
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@Eikonizo
Eikonizo Therapeutics
1 year
@Eikonizo is excited to be in Philly for the @alzassociation #AAIC24. A great opportunity to learn from and meet with some of the best and brightest in dementia research. If you see our CEO @RickLundberg, be sure to stop and say hello!
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@JohnOBrennan2
John O’Brennan
1 year
Wow. The Harris team are out of the blocks in lightening quick time with this superb ad
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@ACSChemNeurosci
ACSChemNeurosci
1 year
📢Stay up to date with the latest📢 This new collection of #ACSChemNeuro research joins the discussion around #MDMA as a potential breakthrough therapy Read the latest research ➡ https://t.co/PiwSg7FvIJ
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@Eikonizo
Eikonizo Therapeutics
1 year
And that's a wrap on #BIO2024! Our CEO, @RickLundberg, spent a busy few days meeting with #biotech & #pharma industry partners and investors while still making time to enjoy some of the sights in beautiful San Diego.
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@ACSChemNeurosci
ACSChemNeurosci
1 year
📢New collection of #ACSChemNeuro research as the FDA is expected to announce a decision on a new treatment involving #MDMA today ⏰ Read the latest research ➡ https://t.co/MiFPxVyOnt
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@ACSChemNeurosci
ACSChemNeurosci
1 year
FDA Advisory Committee votes against recommending Lykos' #MDMA treatment for PTSD Read our latest MDMA research here ➡ https://t.co/iFVKFwAa7U
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@jmhooker
Jacob Hooker
1 year
@ACSChemNeurosci @zenbrainest Super interesting discussion about expectancy bias… check out
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pubs.acs.org
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@jmhooker
Jacob Hooker
1 year
Overall, I thought the discussion was less focused on the tremendous unmet need. Maybe I’m a bit too cavalier, but I certainly felt the benefits outweigh the risks (with plenty of guardrail caveats).
@ACSChemNeurosci
ACSChemNeurosci
1 year
@jmhooker @zenbrainest want to kick off the discussion?
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@ACSChemNeurosci
ACSChemNeurosci
1 year
Fascinating discussions online today surrounding the FDA's consideration of a new #MDMA treatment for PTSD 🤔 When is a double-blinded study not enough? How can you blind for a treatment that includes such pronounced and well-known effects? Let us know what you think! ⬇
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@bsw5020
Brian Wallach
1 year
Today the world can watch a film that has been called “the best movie I have seen in 30 years.” For Love & Life: No Ordinary Campaign is now streaming on @PrimeVideo. After you watch the documentary, please review it on the Amazon page for the film. https://t.co/FO3gvK8Bhj
amazon.com
A deeply moving documentary illustrating the transformative power of love, hope and activism. The film follows Brian Wallach and his wife Sandra after his ALS diagnosis at age 37. Anchored by a deep...
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@zenbrainest
BryanRoth
1 year
Whoo hoo! Major paper now out in @science : "AlphaFold2 structures guide prospective ligand discovery" Collaboration with @RothLabUNC @BShoichet Skiniotis, Kruse, @EnamineLtd
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@Nature
nature
2 years
An orangutan in Sumatra surprised scientists when he was seen treating an open wound on his cheek with a poultice made from a medicinal plant
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nature.com
Nature - The Sumatran orangutan used a plant known to humans for its medicinal qualities.
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@PNASNews
PNASNews
2 years
Neuroimaging, blood proteomics, and health data from 30 military personnel show that increased exposure to explosive blasts was associated with structural and functional brain alterations and a decrease in health-related quality of life. In PNAS: https://t.co/lCOTXM1S0i
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@jmhooker
Jacob Hooker
2 years
Really excited to share the hard work of a killer team. This project was a long time in the making and hit the COVID shutdown timeline and “penalty” but the team saw it through and it’s really great science. @ACSCentSci
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pubs.acs.org
Cyclooxygenase-2 (COX-2) is an enzyme that plays a pivotal role in peripheral inflammation and pain via the prostaglandin pathway. In the central nervous system (CNS), COX-2 is implicated in neurod...
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@MGHMartinos
MGH Martinos Center
2 years
Multidisciplinary team at @MGHMartinos @MGH_CNTR studied 30 active-duty U.S. Special Operations Forces: https://t.co/hcqjtddoP6 Increased blast exposure was associated with structural, functional and neuroimmune changes in the brain detected by MRI & PET: https://t.co/bfm895SVII
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@ComaRecoveryLab
Brian Edlow
2 years
Impact of Repeated Blast Exposure in Active-Duty U.S. Special Operations Forces: https://t.co/lA3rqmi8MX We thank the 30 SOF participants, who bring the military one step closer to a diagnostic test for repeated blast brain injury. @MGHNeurology @MGHMartinos @MGH_CNTR
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