Lee Lab
@jklee_lab
Followers
1K
Following
1K
Media
24
Statuses
510
Our lab @dgsomucla @uclajccc studies the functional genomics of cancer and develops cancer immunotherapies. #prostatecancer #bladdercancer #physicianscientist
Los Angeles, CA
Joined August 2019
Check out our efforts on combinatorial genetic modeling of cancer out now @NatureGenet. Special thanks to @FaltasLab @HsiehLab Michael Haffner @fredhutch and @BladderCancerUS @NIH_CommonFund @CDMRP @MissionBio. @UCLAJCCC @UCLAstemcell @parkerici @PCFnews
https://t.co/vLXSaqYfQY
nature.com
Nature Genetics - An approach combining infection of primary human epithelial cells with a barcoded lentiviral-based library followed by engraftment into mice yields biologically relevant models of...
12
29
123
Happy to see our work on an advanced CAR-T cell therapy for prostate cancer out now @natBME (open access). It was so nice to work with @BioengIshihara, @jklee_lab, @vipulbhatia24, @yutaAsano1991 and all the collaborators. https://t.co/kwCt5KC5WA.
nature.com
Nature Biomedical Engineering - CAR-T cells are engineered to express CBD-IL-12 upon STEAP1 recognition to enhance tumour-specific immune responses in mice.
1
3
8
Closing out DoM Research Day, Dr. John Lee provides the latest from his lab with an overview of the development and first-in-human clinical translation of chimeric antigen receptor and T cell receptor-transgenic T cell therapies targeting prostate and bladder cancer.
0
2
11
First-in-human phase I/II clinical trial of STEAP1 CAR T cell therapy for mCRPC now open to enrollment! NCT06236139 PI: @JessicaHawleyMD @fredhutch #NExT Program @NCItreatment
5
17
67
The new California Institute for Immunology and Immunotherapy at the UCLA Research Park aims to make LA the center of scientific innovation. Immunotherapy treatments are revolutionizing cancer care, and show promise in treating other diseases. Read more: https://t.co/KGrYrurOoT
1
9
32
Looking forward to the superstar @JessicaHawleyMD presenting @AmerUrological #AUA24 on T cell Tx for advanced GU cancers, current landscape for T cell engagers & autologous T cell Tx, upcoming trials, eg. IIT STEAP1 CART (NCT06236139), to open @fredhutch scientificPI: @jklee_lab
0
1
10
The Agency has given us the "study may proceed" for our first-in-human STEAP1 CAR T trial for mCRPC https://t.co/TRRbbNMyQa led by @JessicaHawleyMD @fredhutch! Truly a collaborative effort to tackle prostate cancer! @PCF_Science @CDMRP @Prostate_IPCR @NCItreatment
7
11
70
Dear colleagues with interest in GU cancers:we are hiring GU Med Onc clinician with focus on patient care & trials accrual! Spread the word! @fredhutch @UWMedicine @JessicaHawleyMD @spsutkaMD @gorejohn @DanLinMD @uwurology @HsiehLab @jklee_lab @OncoAlert
https://t.co/tTEt7BxnGw
careercenter.asco.org
The University of Washington (UW) Department of Medicine, Division of Medical Oncology is recruiting for a full-time clinical faculty member
1
10
48
Please RT Looking for vibrant energetic RAs to help with our research and translation to the clinic #ProstateCancer #CellPlasticity #Epigenetics #TME #Therapy @CPDR_Labs @nciccr_gmb @PCF_Science @jobRxiv
0
24
28
Incredibly honored to be elected to @the_asci! Very thankful to many mentors/supporters: @ToniRibas12, Owen Witte, @IntMedAbel, Pete Nelson, @HsiehLab, and @felixfengmd. #doubledocs @UCLAJCCC @parkerici @UCLAstemcell @fredhutch
We are pleased to announce the election of 100 new Active and International members for 2024. See the full list here: https://t.co/sipalWEZTu These members will be officially inducted on April 5, as part of the 2024 AAP/ASCI/APSA @JointMeeting!
11
5
58
Thanks to @UCLAJCCC @UCLAstemcell @UclaMcdb @UclaUrology for supporting our work. Pretty much all of my prior publications were small and took just a few years to complete. This one was different and required a lot of work, funding, and patience. So happy to have it out!
New paper out now in @NatureCellBio & led by @ASGoldstein6 helps explain why some prostate cancers become resistant to hormone therapy, laying the groundwork for developing improved therapies for treatment-resistant prostate tumors. https://t.co/n4zRWS9qLW
4
5
50
An opportunity to engage in cancer, immunology and metabolism research in my lab Job Opening ID: 308463 - Laboratory Research Assistant - IN-UROL #minorities are encouraged to apply For external candidates this is the link: https://t.co/P3N15yu1Qj
hrms.indiana.edu
Find your place at Indiana University. Explore faculty and staff positions on our seven campuses for a healthy, enriching, and balanced work life.
3
3
7
Congrats to Galina Semenova @fredhutch for her @PCFnews Young Investigator Award! She is soon to reunite with us @uclajccc!
CONGRATULATIONS to the Class of 2023 @PCFnews Young Investigator Awardees!!! 🥳🥳🥳👏👏👏🎉🎉🎉 We are so proud to fund these early career physicians and scientists who are committed to advancing the #ProstateCancer field!! https://t.co/0TjU1cS78X
4
4
41
Trainees in urological research--register for #SBUR2023 in San Antonio, TX on November 9-12 https://t.co/M1Q8JuEKuo and attend the Trainee Symposium! We have a great lineup of speakers and panelists to provide career advice--check out the flyer. @UrologySBUR
0
4
19
Impressive safety & efficacy data by Dr. Kelly on T cell engager targeting STEAP1 (xaluritamig)published in @CD_AACR supporting more development @myESMO @OncoAlert @JessicaHawleyMD @neerajaiims @DrChoueiri @TiansterZhang @DrRanaMcKay @urotoday @jklee_lab @HsiehLab @DrScottTagawa
0
13
37
Don't miss! #ESMO23 presentation by William Kelly - 1765O - Interim Results from a phase 1 study of AMG 509, a STEAP1 x CD3 XmAb 2+1 immune therapy, in patients with #mCRPC > https://t.co/LqaIlT4hJe
@myESMO
0
3
3
Looking to grow our computational team. Come and join a dynamic group and help us find an end to #ProstateCancer-Bioinformatics Research Associate II - Bethesda, Maryland @PCF_Science @nciccr_gmb
0
8
19
Very happy to share this collaborative effort published today @CRC_AACR with Colm Morrissey, Pete Nelson, @AlumkalJoshi, and others @UW and @fredhutch! @Prostate_IPCR @PCF_Science
Just published: Concurrent targeting of HDAC and PI3K to overcome phenotypic heterogeneity of castration-resistant and neuroendocrine #prostatecancers, by Zhang et al. https://t.co/hVzM9yKviq
@fredhutch #openaccess
3
7
37
Looking for a motivated postdoctoral fellow to lead research involving #prostatecancer #DNAdamage #epigenetics #therapeutics - Join a vibrant team at Center for Prostate Disease Research, @USUhealthsci @WRNMMC_DHA @nciccr_gmb
0
28
57
We’re hiring! (2x technicians and a post-doc) Are you interested in the molecular and epigenetic drivers of neuroendocrine prostate cancer development? Want to use novel GEMMs and organoid models? Look no further! Reach out to dsr2005@med.cornell.edu for more information.
0
9
15