
UCLA Broad Stem Cell
@UCLAstemcell
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Supporting innovation, excellence and the highest ethical standards focused on taking stem cell discoveries from the lab to the patient. (RT≠endorsement)
Los Angeles, CA
Joined June 2015
🔬For 20 years, our scientists have been redefining what’s possible in regenerative medicine — trailblazing therapies, transforming lives and shaping the future of human health. Dive into our story: https://t.co/VJBzi964pa
#StemCellScience #RegenerativeMedicine
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Ever wondered what makes stem cells so special? 🧫🔬 Stop by an interactive stem cell research exhibit at Powell Library to learn about the science that’s rewriting the future of human health. @UCLALibrary @UCLA
#StemCellAwarenessDay
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On #StemCellAwarenessDay, we reflect on CIRM’s mission since 2004: advancing stem cell & gene therapy research in California. To date, we've approved $4.6B to support innovation, education, & infrastructure. Take this fun quiz made by a CIRM Scholar: https://t.co/y3bjVuSfKb
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The FDA has approved Phase I clinical trials for a groundbreaking heart tissue regeneration drug developed by @UCLA cardiologists — funded entirely by taxpayer dollars. #ResearchPowersProgress @UCLAHealth @dgsomucla
https://t.co/mm0xiO0jIY
stemcell.ucla.edu
The body’s tissues can get injured in many ways, but while some injuries heal perfectly, others don’t heal at all. A cut in the skin, for example, usually heals all on its own, while internal organs,...
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Our center director, Dr. @Thomas_Rando, is among the 13 distinguished researchers who have joined the @stemcellreports Editorial Board! 📖
Stem Cell Reports welcomes new researchers to its Editorial Board. Their appointments reinforce the Board’s commitment to championing the journal, raising its global visibility, and ensuring rigorous, high-quality peer review. Read more: https://t.co/4EQadrxNFg
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After decades developing a proven gene therapy for ADA-SCID, @UCLA's Dr. Donald Kohn talks to @nytimes about his new mission: getting the life-saving therapy to the patients and families who've been waiting years. #ResearchPowersProgress
nytimes.com
Gene therapies for rare diseases are frequently developed then discarded by drug companies because they can’t afford to produce the treatment for more patients.
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Professor William Lowry is using stem cell research and an NIH grant to tackle health issues from baldness to cancer. Learn more about how UCLA #ResearchPowersProgress: https://t.co/csX403THnT
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UCLA scientists have received $4.7 million in @CIRMnews grants to advance stem cell-based treatments for female-specific diseases & childhood leukemia in Down syndrome. Congratulations to Dr. Kathrin Plath & Dr. Hanna Mikkola! #ResearchPowersProgress ➡️ https://t.co/0ehPzyoKTc
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CIRM has allocated $8M to support a @UCSFBenioffOAK & @UCLAstemcell trial using CRISPR to fix the mutation that causes #SickleCellDisease. This first-of-its-kind approach could help prevent complications before they start. Learn more: https://t.co/rGLxayfMjx
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Join us on Thursday, October 2 as Dr. @AlexShcheglovit 🇺🇦 of @UUtah presents, "Neural rosette-based brain organoids: A controlled stem cell-derived model to study human neurodevelopment and disease” at 12pm in CHS 13-105. Register today: ➡️ https://t.co/KvMgavy0rj
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A @UCLA study from the lab of Melody Li reveals how some mosquito-borne viruses, including chikungunya, breach the blood-brain barrier — and points toward new ways of stopping them. 🦟🧠 #ResearchPowersProgress
newsroom.ucla.edu
The findings reveal precise viral-host interactions that could be targeted with new antivirals or vaccines.
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Dr. Melody Li's team recently investigated alphavirus-blood-brain barrier interactions by pairing a physiologically relevant, hPSC-derived model of brain microvascular endothelial-like cells with sindbis virus strains of opposite neuroinvasiveness. 📖 More details here:
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Evie Junior, born with #SickleCellDisease, participated in a CIRM-funded trial at @UCLAstemcell, using his own modified stem cells. He’s now free from pain crises and meds. This #SickleCellAwarenessMonth, we highlight the promise of curative therapies. https://t.co/QCgAjq7Tog
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UCLA researchers have made strides in developing a stem cell gene therapy for alpha thalassemia major, a severe, inherited blood disorder in which patients lack the gene needed to produce hemoglobin.
newsroom.ucla.edu
In patient cells in culture, the gene therapy successfully restored normal alpha-globin protein production to healthy levels.
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In a 2024 study, @cnsiatucla member Donald Kohn (@UCLAstemcell) and a @UCLA team developed a stem cell gene therapy that could offer a one-time cure for children with alpha thalassemia major: https://t.co/yZudUSwmn9
#ResearchPowersProgress
cnsi.ucla.edu
Thanks to groundbreaking in-utero blood transfusion technology, what was once a fatal diagnosis in the womb can now result in live births. However, this medical advancement created a new challenge: a...
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A @UCLA research team led by Dr. Donald Kohn @Kohn_Lab is developing a one-time stem cell gene therapy treatment for deadly blood disorder alpha thalassemia major that’s potentially curative. #ResearchPowersProgress
newsroom.ucla.edu
In patient cells in culture, the gene therapy successfully restored normal alpha-globin protein production to healthy levels.
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What a wonderful weekend at the 2025 PICI retreat! Grad student Chris Ochoa had a presentation on cellular lineage of gynecologic carcinosarcomas & immune targeting. SRA Lauryn Ruegg had a poster on novel strategies to target unique vulnerabilities in ovarian cancers.
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Congratulations to Dr. Dawn Ward of the @UCLA Human Gene and Cell Therapy Facility for receiving a G-Rex Grant that will support production of a novel iNKT cell therapy developed by Dr. Lili Yang! 🦠🧪🧫 🔗 https://t.co/J1IsrmHige
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CIRM-funded @UCLAstemcell researchers reprogrammed blood stem cells to produce #cancer-targeting T cells—offering a renewable path for immunotherapy. Early results are promising for treatment-resistant tumors. https://t.co/6vB5hKgvI2
stemcell.ucla.edu
In a first-of-its-kind clinical trial, UCLA scientists have shown it’s possible to reprogram a patient’s blood-forming stem cells to generate a continuous supply of functional T cells, the immune...
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Video shows neural activity in hippocampal assembloids derived from patient stem cells. In the healthy control (L), neurons fire independently. In the assembloid w/ the SCN8A gene variant (R), neurons fire together in sudden flashes — an abnormal pattern associated w/ seizures.
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Using #stemcell models, @UCLA scientists find how epilepsy genes disrupt different brain regions. The study establishes the first hippocampal assembloid model, creating a new platform for studying epilepsy, autism and Alzheimer’s disease. 🔗 https://t.co/U0XxlVJ7L4
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