
Bull Group Chemistry
@jamesabull
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Organic Chemistry Research Group at Imperial College London. Synthesis; Catalysis; Heterocycles. Updates on group news and papers. Account run by JAB
Imperial College
Joined June 2009
RT @ChemistryEur: New orthogonal SuFEx and SNAr reactivity of sulfonimidoyl fluorides and the automated synthesis of sulfonimidamides by @j….
chemistry-europe.onlinelibrary.wiley.com
GA: Sulfonimidoyl fluorides react with a diverse set of amines in a HOBt-catalyzed sulfur(VI) fluorine exchange reaction to access sulfonimidamides, including directly NH-sulfonimidamides, and in an...
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Our work on the divergent synthesis of difluorocyclobutanes, now published in #JOC @JOC_OL. Synthesis of gem-Difluorocyclobutanes: Organolanthanum Enabled Synthesis and Divergent Catalytic Functionalization of gem-Difluorocyclobutanols
pubs.acs.org
Fluorinated cycloalkyl motifs continue to receive intense interest in medicinal chemistry due to their potential to modulate physicochemical properties. In recent years, this interest has extended to...
Interested in strained rings or fluorine for medicinal chemistry - check out Hikaru’s work on divergent synthesis of difluorocyclobutanes, on ChemRxiv:.
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SuFEx and SNAr on Sulfonimidoyl Fluorides - pleased this is now published in @ChemistryEur. Catalytic SuFEx Reactivity of Sulfonimidoyl Fluorides with Functionalized Amines with Automation Applicable Conditions
chemistry-europe.onlinelibrary.wiley.com
GA: Sulfonimidoyl fluorides react with a diverse set of amines in a HOBt-catalyzed sulfur(VI) fluorine exchange reaction to access sulfonimidamides, including directly NH-sulfonimidamides, and in an...
Happy to report our work on catalytic SuFEx with sulfonimidoyl fluorides - and switchable SNAr reacts also. Congrats to Nikki on her paper now on ChemRxiv.
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Electrochemical Copper Catalysis: A Triple Catalytic System for Transient C(sp2)–H Functionalization Through Mediated Electrolysis | @ChemRxiv .Congrats Freeman @TszKanMa1 .
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Congrats to Freeman and Peerawat on our recent @ChemRxiv - Synthesis of Cyclic Sulfilimines and Sulfoximines via Copper Mediated C(sp2)–H Sulfanylation of Benzylamines with a Catalytic Transient Directing Group.
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** New PhD position ** We are advertising a chemical biology studentship with Profs Vilar and Mann, in collaboration with GSK, with ICB CDT @icbcdt . #automation, #Synthesis, #D2B. Fully funded at UK fees level.
findaphd.com
PhD Project - Development of automated workflows for direct-to-biology drug discovery of kinase inhibitors at Imperial College London, listed on FindAPhD.com
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RT @drughunter_com: Did you miss Ulrich Luecking’s talk about "Sulfoximines in Medicinal Chemistry: Unlocking Novel Opportunities in Drug D….
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RT @LcsoLab: Last update of our "useful link" website: we added a few computational tools and compound databases useful for organic chemist….
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We are advertising a 2nd fully funded PhD studentship with @TateScience and @icbcdt for October - .New dimensions for covalent enantioprobe chemoproteomics .#chemicalbiology, #synthesis, #chemoproteomics, #CHfunctionalisation.
findaphd.com
PhD Project - New dimensions for covalent enantioprobe chemoproteomics at Imperial College London, listed on FindAPhD.com
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RT @CheMResImperial: 🌟 Unlock Your Potential in Advanced Molecular Synthesis! .Join the MRes in Advanced Molecular Synthesis at @imperialco….
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RT @icbcdt: 🚀 Exciting Opportunity! We're offering 5 studentships for October 2025 entry at @imperialcollege:. 🔬 1+3 studentships (1-year M….
imperial.ac.uk
2025 Studentship Opportunities
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We are advertising an exciting PhD studentship related to covalent drug discovery with @TateScience and Vertex pharmaceuticals. Warheads take the strain in chemoproteomics #Synthesis, #Strained_rings, #Chemoproteomics. Applications through ICB CDT @icbcdt:.
imperial.ac.uk
2025 Studentship Opportunities
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We are recruiting for a postdoctoral Research Associate in Synthetic Chemistry to work in C-H functionalisation. Come join us @impchemistry! 3-year position. Closing 19-March-2025. #Chempostdoc, #CHfunctionalization, #Heterocycles.
imperial.ac.uk
Please note that job descriptions are not exhaustive, and you may be asked to take on additional duties that align with the key responsibilities ment...
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The RSC Organic Chemistry Community South-East Regional Meeting will be hosted by Imperial Chemistry @impchemistry on Friday 28th March 2025 with an excellent speaker line-up. For more details, to register, & submit poster abstract (PhD/PDRAs), see here:
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Our latest on oxetanes and azetidines. Congratulations and thanks to the team!.
Harnessing Oxetane and Azetidine Sulfonyl Fluorides for Opportunities in Drug Discovery | Journal of the American Chemical Society @ImperialSci.@imperialcollege @impchemistry #Oxetane #Azetidine #SulfonylFluoride #DrugDiscovery @TotalSyntheses
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RT @J_A_C_S: Harnessing Oxetane and Azetidine Sulfonyl Fluorides for Opportunities in Drug Discovery | Journal of the American Chemical Soc….
pubs.acs.org
Four-membered heterocycles such as oxetanes and azetidines represent attractive and emergent design options in medicinal chemistry due to their small and polar nature and potential to significantly...
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