Our new preprint led by @eliscanu96 on modeling multiple genotypes/phenotypes of extra-chromosomal DNA is online. Glad that Elisa will continue to work on the application of her theoretical work on experimental and biological context. stay tuned! .

RT @EvoGamesPlus: After intense research discussions, day 2 wrapped up with an alternative Prague tour exploring underground gems!🚇🎨. EvoGa….

#EvoGamesPlus.

Do you agree with @Plektix ‘s assignments of the right evolutionary theory to the right person in Beatles?

RT @EvoGamesPlus: Day 3 of the Open End Conference is in full swing with in depth discussion sessions! 👩‍🔬🌍 . EvoGamesPlus researchers are….

RT @EvoGamesPlus: EvoGamesPlus Open-End Conference kicks off today in Prague! 🎉🎉 Discussion sessions, invited speakers, early stage researc….

RT @EvoGamesPlus: Wrapping up the early stage researcher talks on day 1 of the conference, we had insightful presentations from Christo Mor….

RT @CancerGrand: Today #CancerGrandChallenges team eDyNAmiC and their international collaborators published 3️⃣ papers in.@Nature 📣. They s….

RT @kinglhung: First of all, this was a great collaboration with co-lead authors @MattG_Jones @ivywtl EJ Curtis @mischellab @HowardYChang a….

Thanks for having us in the team!

RT @chilbe3: 📢 JOB ALERT: Post-Doc position 📢.Please join our group, and explore human social behavior on a fully funded 3y Post-Doc positi….

@BenjaminWerner_ Counterintuitively, the highest fraction of mix cells with both ecDNA types is maintained under intermediate rather than high switching probabilities.

This is a joint work with @BenjaminWerner_ . By using a minimal model with different values of switching probabilities (p) between different ecDNA types, we analyse dynamics of ecDNA genotypes through genetic mutations (small p) and ecDNA phenotypes by larger switching rates.

RT @BenjaminWerner_: A new preprint on the spatial temporal evolution of ecDNA amplified oncogenes in Glioblastoma. Great joined effort o….

Finally online: Accumulating waves of random mutations before fixation with Marius Moeller and @BenjaminWerner_ .

RT @QingliGuo: Thrilled to share our discovery of novel long-deletion #signatures—powerful markers for tracking #MMRd #CancerEvolution, eve….

RT @alexstein_: New manuscript with @BenjaminWerner_ online on bioRxiv!! 📑Our manuscript provides a theoretical investigation of genetic i….

Correspondingly, we observe cycles in antigenicity and immunogenicity dynamic coupled with irregular spikes in the population size.

In low immune effectiveness, we see little deviations compared to neutral expectation without cancer-immune interaction. When the immune system plays a larger role, significant difference is observed in those genetic markers, especially in the mutation burden information.