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Morten Orebo Holmström Profile
Morten Orebo Holmström

@holmstrom_mo

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MD, tumor immunologist and passionate surfer. Based at @CCITdk. Occupied with #immunotherapy for #MPNsm and #cancer in the #pancreas

Joined January 2021
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@holmstrom_mo
Morten Orebo Holmström
10 months
RT @CCITdk: 📣 PhD course "Cancer Immunology and Immunotherapy", 4th edition.📃 Course Description and registration 👉.
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@holmstrom_mo
Morten Orebo Holmström
1 year
New publication on #MPNsm from @CCITdk published in @BrJHaem: Peripheral blood lymphocytes (PBL) from patients with CALR mutant #MPNsm display increased levels of surface TGFb and GARP. Probably mediated by enhanced binding of activated platelets to PBL.
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onlinelibrary.wiley.com
T cells (green) and NK cells (purple) from patients with CALR exon 9 mutant myeloproliferative neoplasms display increased expression of LAP and GARP on their cell membrane compared with patients...
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@grok
Grok
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Join millions who have switched to Grok.
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@holmstrom_mo
Morten Orebo Holmström
2 years
Why go abroad for scientific talks when you can have the best at @CCITdk?.A huge thanks to the presenters during the last week @VPrasadMDMPH, @Alfdoc2 and @MadsMelbye, and to @DoniaMarco for organizing. 🙏
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@holmstrom_mo
Morten Orebo Holmström
2 years
As always a great honour and pleasure to present the potentials and perspectives of cancer #immunetherapy in #MPNsm at the @DanishMPN Patient Society annual meeting. Conclusion of the talk: We still have a lot of work to do at @CCITdk 🩸💉🧬🔬
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@holmstrom_mo
Morten Orebo Holmström
2 years
New publication from @CCITdk on #MPNsm. CALR specific T-cells induced by therapeutic vaccination fail to enrich in the bone marrow.💉. Transformed cells outnumber effector immune cells. The latter could impact the efficacy of immune therapy in MPN.
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@holmstrom_mo
Morten Orebo Holmström
2 years
Yay! First post-pandemic tumor immunology conference for me #cimt2023 🥳.Really nice talks. Amongst those a talk by @TheVinodLab on personalized mRNA cancer vaccines in #pancreas cancer inducing an amazingly high fraction of neo-antigen specific T-cells. Fascinating!.@C_IMT
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@holmstrom_mo
Morten Orebo Holmström
2 years
So exciting to attend the @GsgMpn annaul meeting in Aachen. Very interesting talks! Thank you to organizers @brummendorf and @SteffenKoschmi1 for inviting me to talk about cancer #immunetherapy in #MPNsm.@UniklinikAachen.@RWTH
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@holmstrom_mo
Morten Orebo Holmström
2 years
So well deserved!.
@CCITdk
CCIT-DK: National Center for Cancer Immune Therapy
2 years
#DSKO23 Danish Oncology Prize 2023 awarded to our Director, Professor Inge Marie Svane. Congratulations!
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@holmstrom_mo
Morten Orebo Holmström
2 years
Our newest publication from @CCITdk on TGFb-specific T-cell immunity in patients with pancreatic cancer receiving radiation therapy combined with cancer immune therapy. A big thanks to @novonordiskfond / @UCPH_BRIDGE and others for funding.
@jitcancer
Journal for ImmunoTherapy of Cancer
2 years
New #JITC article: Pre-existing TGF-β-specific T-cell immunity in patients with pancreatic cancer predicts survival after checkpoint inhibitors combined with radiotherapy @holmstrom_mo
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@holmstrom_mo
Morten Orebo Holmström
2 years
Over and out from my last @UCPH_BRIDGE course. Now time to reconnect with the Mothership at @CCITdk and continue the search for the #cureforcancer 🧬💉🧪
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@holmstrom_mo
Morten Orebo Holmström
3 years
Teaching the next generation a few things about #flowcytometry and #FACS at @CCITdk
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@holmstrom_mo
Morten Orebo Holmström
3 years
Antibodies to mutant CALR in serum from healthy donors. Yet another evidence of tumor immune surveillance against CALRmut #mpnsm. Thanks to Gunnar Houen, @DrFassi and others for a nice collaboration on this project. @CCITdk.
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@holmstrom_mo
Morten Orebo Holmström
3 years
We thank @HerlevGentofte Hospital for supporting the last dataclub at @CCITdk with X-mas sweets. Ho ho ho 🎅
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@holmstrom_mo
Morten Orebo Holmström
3 years
Some of my colleagues at @CCITdk made it to the @NEJM this week. Impressive work! Congrats to all of you. 👏💪.
@CCITdk
CCIT-DK: National Center for Cancer Immune Therapy
3 years
Treatment with tumor-infiltrating lymphocytes (#TILs) is a safe and effective treatment for advanced #melanoma. A decade of academic efforts by @CCITdk and @NKI_nl published on the @NEJM.Funding @cancer_dk @RegionH @HerlevGentofte and Dutch organizations.
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@holmstrom_mo
Morten Orebo Holmström
3 years
RT @MPN_Hub: Congratulations to Hans Hasselbalch on receiving the Medical Excellence Award during the 14th International Congress on MPN #M….
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@holmstrom_mo
Morten Orebo Holmström
3 years
Absolute and utter brain hard wiring 🤯😵‍💫🥴 doing #DAG / #directedacyclicgraph and #causalinference at the @UCPH_BRIDGE Big Data II course with a very patient @HRytgaard as teacher .#MachineLearning
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@holmstrom_mo
Morten Orebo Holmström
3 years
Peptide vaccines against mutant CALR incite strong T cell responses in patients with CALRmut #mpnsm but don't show any clinical effect.🤔.These days I perform an experiment at @CCITdk using this wonderfull machine, that will hopefully shed light on the lack of clinical response.
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@holmstrom_mo
Morten Orebo Holmström
3 years
RT @jesper_fisker: Banebrydende forskning 😀👏 T-celleterapi gi'r alvorligt syge modermærkekræftpatienter en ny chance! Så stolt over, at @ca….
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@holmstrom_mo
Morten Orebo Holmström
3 years
RT @CCITdk: Patients' own immune cells can be transformed into a potent #immunotherapy for #melanoma, an aggressive type of skin #cancer.….
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@holmstrom_mo
Morten Orebo Holmström
3 years
Presenting "the mother of all standard curves" with @KatrineBaumann, @song60887727 and @Moelsay at the @UCPH_BRIDGE Translational Tools II course at @UCPH_CPR. Even more impressing considering the fact that 50 % of the pipetters were MDs.🙃.@grith_hojfeldt
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