This @jbiolchem cover image depicts HDAC7 (colored protein) bound on chromatin in complex with Histone H3.3. ➡️"Inhibition of HDAC7 reprograms the histone H3.3 landscape to induce heterochromatin spreading and DNA replication defects in cancer cells" https://t.co/kkFnRnRiRJ

Just Published!⛄️ Histone deacetylase HDAC7 restricts CD8 + T cell tumor infiltration and limits #immunotherapy sensitivity in #bladdercancer: reversal by #pinocembrin Full text 👇 https://t.co/inplR4jV4D #HDAC7 #CD8  #Tcell #TumorInfiltration

👏 Proud of our in-house young & talented researchers! Yesterday, we had inspiring talks from: ▶️Lorea Villanueva on HDAC6 inhibitors ➕ ▶️Alba Azagra on the role of HDAC7 in B-cell development Histone deacetylases rule!

2-phenylbenzoyl hydroxamates are selective for immunological target HDAC7 over HDAC1 and potently inhibit class IIa HDACs : https://t.co/4hN9fFrUkB

Dr. Nikos Tapinos @Tapinos_Lab discusses very interesting results as to identification of HDAC7 as a druggable target in human glioblastoma. Collaboration with bioengineers on hydrogels with siRNA therapeutics are among the most interesting translational directions. The

Correlation between MMP-13 and HDAC7 expression in human knee osteoarthritis https://t.co/nVyScpK3qg

A histone deacetylase 7‐derived peptide promotes vascular regeneration via facilitating 14‐3‐3γ phosphorylation #HDAC7 #peptide #phosphorylation #sORF #vascularprogenitorcell #VEGF #stemcells #regneration https://t.co/95PPRNvnLn

Special day for our lab, with the Thesis defense of our (not anymore) PhD student Alba Azagra! Congrats for the great job and all the best for the future! #hdac7 #anewdoctorishere @idibell_cat @CarrerasIJC

Fantastic talk by my lab colleague @KaustavDasGupt8 on the differing roles of HDAC7 in macrophage inflammatory and antimicrobial pathways. #ASI2022MEL

Researchers show that IL24 is a direct target of HDAC7, and that it suppresses the growth of #CancerStemCells. https://t.co/TyBTQ5IRZk @uniud

And now closing #KSheartfail with the best talk: @austinchsu! SIK1- HDAC7 axis in cardiac hypertrophy @Gladstone_GO @GladstoneInst

Day 2 of #melbimmmetabsym, with my coffee, blanket and ugg boots. An entertaining scientific start to the day with Matt Sweet @TheSweetGroup showing how HDAC7 controls macrophage metabolism @ASImmunology

.@austinchsu @saptarsi_haldar @benoitbruneau @GladstoneInst: Salt-inducible kinase 1 maintains HDAC7 stability to promote pathologic cardiac remodeling https://t.co/VjNCebfSRP #Cardiology #MuscleBiology

Investigators explore the effects of miR-342-3p on #liver #CancerStemCells (LCSC) and related mechanisms. They show that miR-342-3p inhibited LCSC oncogenicity and cell stemness by promoting #PTEN and inhibiting HDAC7. 📎 https://t.co/LN00qDmGMX

[研究成果] メディカル情報生命専攻の合山進教授と張分宇特任研究員（研究当時）らは、赤白血病の治��標的としてHDAC7を同定しました❗️本件研究成果が発展することにより難治性で知られる赤白血病に対する画期的な治療薬の開発が期待されます✨ https://t.co/fCmJ5qIkpD

PATJ, a Crumbs polarity complex protein,⏫epithelial cell #Lumenogenesis #Ciliogenesis PATJ exhibits junctional+ciliary localizations, &⏬HDAC7, a ciliary protein HDAC7 KD rescues morphogenetic defects of PATJ crispant MDCK cells #CellMolLifeSci 2023 https://t.co/JDYbt9M1WK

Proud to say that @MelerAinara's thesis defense was amazing 👏 Ainara, from the @MaribelParraLAB, shone brightly today presenting her work on the role of the transcriptional modulator HDAC7 in B cell development and associated malignancies. Congratulations, new doctor! 🎓🎉

Huang Dingzhi's team from Tianjin Medical University Cancer Hospital discovered a new subtype of HDAC7+ SCLC and revealed the molecular mechanism of the positive correlation between the effect of XPO1 inhibitors and the expression level of HDAC7. #Medical #lungcancer #Tumor

“How can one little protein take so much of one’s life?” I have the same question as Prof. Matt Sweet here who gave a talk in the innate immunity session @ASImmunology about HDAC7- an immunometabolic switch in macrophages. #ASI2022MEL @TheSweetGroup