STEM CELLS Journal
@StemCellsJournl
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STEM CELLS, a peer reviewed journal published monthly, provides a forum for prompt publication of original investigative papers and concise reviews.
Joined December 2014
This study investigated the role of N6 methyladenosine (m6A) in chondrogenic differentiation of bone marrow mesenchymal stem cells.
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METTL3 promotes osteogenesis by regulating N6-methyladenosine-dependent primary processing of hsa-miR-4526.
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Genetic ablation of p16 mitigates premature osteoporosis induced by PTHrP nuclear localization sequence and C-terminal deletion through inhibition of cellular senescence.
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Enrichment of spermatogonial stem cells and staging of the testis cycle in a dasyurid marsupial, the fat-tailed dunnart.
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Bone marrow mononuclear cell transplantation promotes bone healing via gap junction-mediated cell–cell interaction.
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This study makes a contribution to the understanding of the pathophysiology of Huntington's disease. The results reveal the disruptive impact of mHTT on the development of medium spiny neurons that likely contributes to neurodegeneration.
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A serum- and feeder-free system to generate CD4 and regulatory T cells from human iPSCs.
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Patterning effects of FGF17 and cAMP on generation of dopaminergic progenitors for cell replacement therapy in Parkinson’s disease.
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Changes in iPSC-astrocyte morphology reflect Alzheimer’s disease patient clinical markers.
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RT @jan_nolta: Consistent self-organized emergence of hyaline cartilage in hiPSC-derived multi-tissue organoids
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Abstract. Existing protocols for in vitro hyaline cartilage production utilizing human induced pluripotent stem cells (hiPSCs) have several challenges incl
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Decoding the epigenetic and transcriptional basis of direct cardiac reprogramming.
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Extracellular microvesicles/exosomes—magic bullets in horizontal transfer between cells of mitochondria and molecules regulating mitochondria activity.
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A small molecule K-3 promotes PDX1 expression and potentiates the differentiation of pluripotent stem cells into insulin-producing pancreatic β cells.
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First study to investigate the mechanism by which METTL3-mediated pri-miRNA m6A modification regulates human adipose-derived stem cell osteogenesis, presenting a novel therapeutic approach for bone defect repair and regeneration.
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This study demonstrated an unprecedented role of RUNX1 in regulating hematopoietic and mesenchymal fate decisions in human pluripotent stem cells-derived hematopoiesis.
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Senescence accelerated mouse-prone 8: a model of neuroinflammation and aging with features of sporadic Alzheimer’s disease.
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Optimizing approaches for targeted integration of transgenic cassettes by integrase-mediated cassette exchange in mouse and human stem cells.
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RT @jan_nolta: Congratulations to our amazing colleagues @UCDavisHealth for this excellent review in @StemCellsJournl!. Harnessing the dive….
academic.oup.com
Abstract. In our aging society, the degeneration of the musculoskeletal system and adjacent tissues is a growing orthopedic concern. As bones age, they bec
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Interesting work aimed at using marsupial models for next-generation conservation and de-extinction efforts.
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A serum- and feeder-free differentiation process, suitable for large-scale production of iPSC-derived CD4sp and regulatory T cells, is reported here.
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