A uniquely dysfunctional set of T cells develops early in #NSCLC and may contribute to #CheckpointBlockade resistance, according to mouse study by @MIT researchers. https://t.co/4AjDWlvjnV

Cross-talk between innate immune cells helps to enhance the antitumor T cell response during #checkpointblockade therapy: https://t.co/w4wSjHVpVs #immunotherapy

Loss of mismatch-repair protein ARID1A in #cancer correlates with high mutation load & #checkpointblockade response, complementing MSI-based prognosis: https://t.co/U7J5euB7P2

Vitamin C has a long history in #cancer research. Now, scientists show high amounts of intraperitoneal #VitaminC delay the growth of many types of tumors and boost the power of immune checkpoint #immunotherapy in mice. @unito #CheckpointBlockade https://t.co/MMSA5ogQYi

A uniquely dysfunctional set of T cells develops early in #NSCLC and may contribute to #CheckpointBlockade resistance, according to mouse study by researchers in @SciImmunology. https://t.co/Mhh7ktYEAS

An exploratory randomized controlled clinical trial of #renalcell carcinoma identifies molecular patterns distinguishing responders to immune #checkpointblockade alone or combined with angiogenesis inhibitor versus angiogenesis inhibitor alone: https://t.co/nhahWTufeU

Excited to be boarding @Delta & headed to @Montreal to give a talk @KeystoneSymp on #Cancer #Immunotherapy efforts from @DaveMess10 @Shawn_M_Jensen @ChilesResearch @ProvHealth @OHSUSOM & @UbiVac to #FinishCancer #OX40 #CheckpointBlockade #PD-1 @Breastcancerorg

Studies in metastatic #melanoma, non-small-cell lung carcinoma and renal cell carcinoma indicate certain bacteria within the #gutmicrobiota enhance clinical responses to #checkpointblockade: https://t.co/OOFkIM1eeK

Preliminary evidence from two cases suggests that fecal microbiota transplantation may provide a viable treatment option for a severe adverse effect of immune #checkpointblockade therapy in patients with cancer: https://t.co/IzskPReCRm

An algorithm-selected gene signature focused on tumor immune evasion and suppression predicts response to immune #checkpointblockade in melanoma, exceeding the accuracy of current clinical biomarkers: https://t.co/IjeiLDfSg2 #immunotherapy

A class of bispecific antibodies that boosts the cancer-killing power of anti-PD-1 #immunotherapy in mice could allow for safer combination treatments based on #checkpointblockade. @Regeneron https://t.co/UuZOqW3TtX

In a multicenter phase 1 trial, scientists at @CIBERONC find that the localized, immune-stimulating compound BO-112 can shrink tumors and sensitize previously-resistant cancers to approved #CheckpointBlockade treatments. #Oncology https://t.co/eeFVV6kAZJ @ScienceTM

Blocking WNT/b-catenin pathway in #NSCLC with a high tumor mutational burden helped overcome resistance to #CheckpointBlockade therapy in mice. https://t.co/vZmGoOpvQH

A gene signature identified in spontaneously regressing neuroblastoma identifies responders to immune #checkpointblockade among patients with #melanoma with accuracy superior to previously reported biomarkers: https://t.co/oIR9G6eUet #immunotherapy

Read about how #MSS tumors with high #TMB respond to #CheckpointBlockade. https://t.co/9HgrUWcQvp #Immune2Cancer #CIM20

Prof Robert Ferris #cancer Center Dir @upmc & #HNSCC GURU /shows #PD1 on #NK Cells & its expression assoc w/improved clinical outcome to #checkpointBlockade #Bridge18 @BMS_ImmunOnc_US @3PSolution *SLIDE SET 1* @headandneckcan @sitcancer

How does the immune system work against cancer? Our video shows 3 types of #immunotherapy, including drugs known as immune checkpoint inhibitors: https://t.co/YfaQEzOEMU #CheckpointBlockade

March issue of NRI is a FOCUS on #CancerImmunotherapy. Find out the latest advances in harnessing the immune system to fight cancer. #checkpointblockade #cancervaccines #tumourmicroenvironment https://t.co/Q5JEmFNgL6

Thanks Prof Melief for introducing one of our speakers at the mechanisms of checkpoint blockade meeting in March 2020 - Jannie Borst, who works on novel checkpoints including CD27!! #BSI19 @bsicongress #immunology #cancer #immunotherapy #checkpointblockade

A new cell manufacturing technique from Miller and Valamehr can readily create high numbers of hard-to-source natural killer cells, which neutralized tumor cells and boosted #checkpointblockade in mouse models of #ovariancancer. @UMNews #Immunotherapy https://t.co/ptRy4kDbE6