Very happy to have this research project from my postdoc with @EKfarley out in Dev Cell! We wondered if single-nucleotide variants within heart enhancers can affect enhancer activity and phenotype.

How to write a scientific paper in fifteen steps. #ScientificPaper #PaperWriting @PLOSCompBiol https://t.co/GDMUxaZi5M

A great cover letter can make or break your manuscript submission. As an editor and author, I've seen how a strong cover letter helps editors grasp your paper’s significance. 🧵 [1/9]

Our work on mesoderm development in 2D gastruloids is now published in Nature Methods: https://t.co/cjb0yGhxCU

Interested in single cell genomics but need help getting started? Check out the full agenda for our Single Cell Genomics Day on Friday 4/25. All talks will be live-streamed (no registration required) at https://t.co/JqaO6urVPF

A red-yellow pigment dial in parrots: Was fortunate to take part in this cool story by my colleague @CorboLab, with Miguel Carneiro, Roberto Arbore, @JindraBrejcha, @M_Miguel_Araujo, et al. A non-coding SNP tunes an enzyme to control feather color:

Updated VISTA Enhancer Browser, 7 years in the making, out in @NAR_Open! >4,500 transgenic in vivo enhancer experiments for all your developmental biology, human variation and #evodevo needs. https://t.co/fE861VE3r7 #enhancers #embryos https://t.co/QxQDzGzBlf

Delighted to be at @ChEnected - American Institute of Chemical Engineers annual meeting at San Diego to meet friends/colleagues and explore exciting science and engineering. We are organizing three ‘Faculty Candidate Sessions’ within Area 15 (Food, Pharmaceuticals, and

Please join us for our 2024 Department of Pharmacology Distinguished Alumni Award and Lecture J. Craig Venter, Ph.D. Date: October 8th, 2024 at 12:00 noon (PST) Location: Biomedical Sciences Building, Liebow Auditorium, 2nd floor

Please RT! @UTD_Biology @UT_Dallas is hiring MULTIPLE faculty. https://t.co/qc3FaIATeq There are 3 priority areas: biochemistry, computational biology, and neurobiology, but we'll also consider ALL research areas that address broad & significant questions in Bio/Biomed sciences.

We had a spectacular Structural Birth Defects/Anomalies meeting at Baltimore the past two days. @StottmannLab and @ZohnIrene were the co-organizers and, along with the organizing committee did an amazing job. @SocDevBio provided logistical support and were amazing as always. /1

We ❤️ MODs! Want an easy way to support model organism databases? Cite them! Depending on the #zebrafish data you retrieve from @ZFINmod, you can show your support by using one of the formats below:

We're cooked.

First look at the genome sequence of Greenland shark to find possible clues that could explain their mind-boggling extreme lifespan of up to 400 years. - 70% of the genome is repetitive elements - many uniquely duplicated genes, many related to DNA repair pathway - p53 is not

My favorate piece of my postdoc work is published! We fused our favorite TFs with a deaminase domain that induces point mutations in DNA, mutagenizing TF binding sites across the genome. Will be a great reagent for exp. evo., as its name suggests :)

Enhancers have piqued the interest of researchers since their discovery in the early 1980s. In his lab @UCIrvine, geneticist @evgenykvon studies how they regulate gene expression during mammalian development. Learn more in this interview: https://t.co/XtUZ8P2HW5

Excited to share the white paper for the IGVF Consortium, supported by @genome_gov Deciphering the impact of genomic variation on function https://t.co/RxudNoG4QG

Happy to share CREsted, our latest package on enhancer modeling! CREsted allows for training sequence-based deep learning models from scATAC-seq data, enhancer decoding and enhancer design through a variety of methods. Check out the GitHub here: https://t.co/hesNelFprs. [1/9]

This is a fascinating article about the discovery of the first transcriptional activator gene. Jacob, Monod and others were skeptical of the positive control model. Of course today we know that it's much more widely used mechanism than repression. https://t.co/fVHcWw8Bzs

Loss of ETS sites in the ZRS enhancer of Shh has been linked to limb reduction in snakes. Here is another example of independent ETS site mutations in the ZRS linked to fin reduction in some lungfishes. Congrats to all authors of this tour de force study! https://t.co/BvWnWDKnrG