FIDO study
@fido_study
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Febrile Infant Diagnostic Assessment and Outcome (FIDO) Study @perukitweep @Rcollem @NIHRresearch @QUBelfast Tweets by: @timburgD Email: [email protected]
UK and Ireland
Joined March 2022
FIDO study is published. @eClinicalMed .Many thanks to all the authors, collaborators, families and patients for making this study possible. One for PEM JC. Many thanks to @RCollEM for funding and support from @QUBelfast @NIHRresearch @PERUKItweep.
thelancet.com
The AAP and BSAC CDAs are highly sensitive at excluding IBI, with a cost saving to hospital services when compared to a treat all approach. The substitution of CRP for PCT made no difference to the...
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Post Immunisation with MenB and febrile. What is the risk of IBI in this cohort of febrile infants? Another @fido_study publicaton. @timburgD @PERUKItweep @Damian_Roland @DrMBarrett @IPEM2025 @AssocPEM @danihalltweets .
mdpi.com
Objectives: To report the prevalence of invasive bacterial infection (IBI) in febrile infants ≤90 days presenting to hospital within 72 h of meningococcal B (MenB) immunisation. Methods: A secondary...
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RT @2_paeds: Our final podcast of 2024 drops tomorrow as we team up again with @PERUKItweep to discuss the @fido_study with lead author @ti….
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RT @PERUKItweep: Our latest podcast is now live! . We chat with @timburgD about the @fido_study - decision making tools in febrile infants.….
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RT @Damian_Roland: Always a pleasure listening to @timburgD discussing @fido_study. His enthusiasm a driving factor in the study’s success….
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RT @EAPaediatrics: 🌡️ Parents need to know: After negative cultures, home care is often safer for febrile infants. Early discharge reduces….
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RT @DemetriAth: Another one with team PEM MSc @spiroskarageo @helenawilcox27 - How should we assess febrile infants with a positive viral r….
dontforgetthebubbles.com
Explore the initial management of a young infant with a positive SARS-CoV-2 swab test. Understand the challenges and potential limitations based on the FIDO study.
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RT @tomasbreslin: Congrats @timburgD and team on your excellent lancet publication! Proud to have you here @MMUHED1 @MaterTrauma @Mater_ICU….
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RT @YaraAlGoraini: 🚨Clinical decision aids (CDAs) for young febrile infants (0-90 days), conducted in the UK & Ireland. Does it revolutioni….
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RT @HannahRubyNB: Huge day for @fido_study. An incredible project…this is one of many great FIDO publications addressing the importance of….
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RT @MeenuPandey_: @fido_study is a practice changing study. Useful messages:. - re-iterates that not all febrile babies <90 days need lumba….
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RT @timburgD: Delighted to see the FIDO study in print. A nice break down in the thread .@DFTBubbles @RCEMLearni….
thelancet.com
The AAP and BSAC CDAs are highly sensitive at excluding IBI, with a cost saving to hospital services when compared to a treat all approach. The substitution of CRP for PCT made no difference to the...
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RT @eClinicalMed: Performance of clinical decision aids (CDA) for the care of young febrile infants: a multicentre prospective cohort study….
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The FIDO study can help clinician have informed conversion with parents and carers about the care of febrile infants through our findings. Also it offers cost analsysis and peformance of tailored care for instutions and policy makers when making a decision on which CDA to adopt.
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The IBI rate in our cohort was 3.7% and E.Coli being the most common organism. Beyound admission and discharge, patients were also ambulated from home indicating an alternative form of managment.
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Main highlights are that the AAP and BSAC CDA offer the best sensitivity and while Arson and NICE fever under 5 had the best specificity. All CDAs were cost effective compared to treat all approach. There was no difference in performance between the AAP with CRP vs PCT.
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The FIDO study gives insight into the peformance of tailored CDA not depedent on PCT testing. It also compares the AAP guidances with CRP vs PCT. The FIDO study recruited over 1800 infants presenting to 35 UK and Irish centres over a 1 year period.
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