
Julie Feldstein,MD
@feldstej
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Chief Pathologist @Histowiz #Telepathology #DigitalPathology #AI @NCI @msk @CAP @mssm #mom #pathpower20 @PathOutlines @ASHScientificCommittee
New York, NY
Joined March 2012
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Cardiac myocytes (heart muscle cells) differentiating from iPS cells photographed through a microscope. Actin filaments and nuclei are shown. #CellBiology
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@feldstej They look like megas with a cohesin defect, such as a stag2 mutation. These peripheral wreath like megas are typical in gata2 deficiency with somatic stag2 variants. I’ve also seen them in the setting trisomy 8 and Cornelia de Lange syndrome (germline cohesinopathy)
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A high-res look inside an inflamed nasal tissue of a patient with chronic eosinophilic #rhinosinusitis! Disrupted #eosinophils and beautiful Charcot-Leyden crystals (blue) revealed by #ElectronMicroscopy! #Pathology #MicroscopyMonday
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