Dani Groves
@daniellegroves_
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Virus photographer 📸 @MRCDTP_IBR PhD student in @nicole_robb1's lab at Warwick Medical School 🦠🔬
Joined December 2021
I am so excited to share that our paper has officially been published in @NAR_Open! We set up the first single-molecule FRET based assay to study inhibition of the SARS-CoV-2 polymerase: https://t.co/AZXcpPAIfw. Thank you to @nicole_robb1, @JeremyKeown1 and @fodorlab members🔬💊
academic.oup.com
Abstract. The COVID-19 pandemic, caused by the SARS-CoV-2 virus, has resulted in significant global mortality, with over 7 million cases reported. Despite
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Just published—avian origin and pandemic PB1 genes from influenza A viruses influence replication and pathogenesis in an avian influenza viirus. Happy for this story to be out and thank you to my co-authors 🦠 #influenza #virology #womeninSTEM
https://t.co/NMv4KlkgNS
science.org
Past influenza pandemics contained polymerase genes from avian influenza viruses, affecting viral replication and pathogenicity.
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An image representing our work made the cover of Biophysical Reports! If you're interested check out the paper at https://t.co/XrimNVZfbp. Thanks again to everyone involved @CVRHutchinson @SwethaVijayakr1 @daniellegroves_ @Hafezelsayyed and not-on-X Andrew McMahon :)
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This year I have two projects available through the BBSRC-MIBTP at Warwick. Both focus on investigating the viral lifecycle of important RNA viruses. Please get in touch if you'd like to hear more. https://t.co/myER6rJL9d
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Check out the preprint for my first paper! Been working on this during my PhD and really happy with what we have achieved
CelFDrive: Artificial Intelligence assisted microscopy for automated detection of rare events https://t.co/yl2Qe7iWOS
#biorxiv_bioeng
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Beyond excited about my first, first author preprint on @biorxiv_micrbio, using single-molecule FRET to assess SARS-CoV-2 polymerase extension and inhibition: https://t.co/M55PJSg4s9 and thanks to all contributors @nicole_robb1 @AndrewPMcMahon @haitian_fan @JeremyKeown1 @fodorlab
biorxiv.org
The COVID-19 pandemic, caused by the SARS-CoV-2 virus, has resulted in significant global mortality and disruption. Despite extensive research, the precise molecular mechanisms underlying SARS-CoV-2...
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Very proud of our latest preprint - using single-molecule assays to explore SARS-CoV-2 replication and inhibition. Thanks to all awesome co-authors @daniellegroves_ @AndrewPMcMahon @haitian_fan @JeremyKeown1 @fodorlab Read it here: https://t.co/zzi3BRDSrF
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Mechanistic insights into the activity of SARS-CoV-2 RNA polymerase inhibitors using single-molecule FRET https://t.co/oqKDNaIg1p
#biorxiv_micrbio
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Very pleased to have been able to present my work at my first Options XII for the Control of Influenza conference in Brisbane, Australia! It’s been an amazing time of meeting old and new colleagues and discussing incredible science 🦠 spot the koala 😉🐨 #influenza @options2024
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🗓️ Join us on Thursday, October 24th at 5 PM BST for an Exciting Seminar with Dr. @nicole_robb1 of @uniofwarwick! 🔬 Mechanistic single-molecule FRET studies of viral replication complexes 📢 Reserve your spot now: https://t.co/R6w1rOVQqs Get insights into SARS-CoV-2
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Thrilled that this finally out - a biophysical model for why viruses form filaments. Thanks as always to all co-authors! @AndrewPMcMahon @SwethaVijayakr1 @Hafezelsayyed @daniellegroves_ @michaelajconley @CVRHutchinson 🦠💚
🚨New paper!🚨 Excited to have played a small part (alongside @CVRinfo's @michaelajconley and @SwethaVijayakr1) in a study where #AndrewMcMahon and @nicole_robb1 ask 'Why do respiratory viruses form filamentous virions?' https://t.co/cInJ7wP7Ll
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Massive congratulations to Dr @AmandaZihanZhu for passing her DPhil viva! Thanks to Ed Hutchinson @CVRHutchinson and @nicole_robb1 for being the examiners and thanks to the llama for the influenza virus polymerase nanobodies!
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Presented at the Warwick Institute of Engagement conference yesterday with @NReddyCycling @C_Cornbill and Shams, discussing how we use social media to share our experiences as PhD students and communicate science to the public 📱🗣️ @warwickengages
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Great to collaborate on this talk with others on the @MRCDTP_IBR , 😁 Sharing content and tips from our experience of using social media for science engagement!
Presented at the Warwick Institute of Engagement conference yesterday with @NReddyCycling @C_Cornbill and Shams, discussing how we use social media to share our experiences as PhD students and communicate science to the public 📱🗣️ @warwickengages
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We loved having all RNAP enthusiasts in Oxford @KavliOxford @lmhoxford @AchillesKap for the 35th RNA polymerase workshop. We loved hearing all your amazing new data and enjoyed this nice research family reunion. Can't wait for the 36th version next year @unibirmingham
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Thoroughly enjoyed getting the opportunity to speak at the 35th UK RNAP meeting! Such a friendly group and lots of great feedback. Huge thank you to @AchillesKap's group for organising @Hafezelsayyed, @jagadishhazra and @ojp25 🔬🧪
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It’s amazing what you can find in 106 yr-old autopsy samples—two, complete 1918 H1N1 genomes! Congrats to the authors and thank you for letting me contribute a small part to this fascinating study 🦠🫁 #flu #virology
https://t.co/QtSbd6Irkn
journals.asm.org
This study applied modern molecular biotechnology and high-throughput sequencing to formalin-fixed, paraffin-embedded autopsy lung samples from two fatal cases during the fall wave of the 1918...
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Seeing this image on a sci journal cover in my school library inspired me to study microscopic worlds - 1st through books and now at the 🔬 ‘So, Nat'ralists observe, a Flea; Hath smaller Fleas that on him prey; And these have smaller yet to bite 'em; And so proceed ad infinitum’
t-bacteriophage viruses injecting their dna into an e. coli to replicate within the bacterium using their tails as syringes (magnification 63,000x). there are more bacteriophages on the planet than every other organism, including bacteria, combined.
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Happy to have this piece of work out looking at the influenza virus polymerase. Produced by the great team of @alaa_baazaoui @CarriqueLoic @fodorlab and @jonathan_grimes.
Structural and functional characterisation of the interaction between the influenza A virus RNA polymerase and the CTD of host RNA ... https://t.co/DC2NvURn5R
#biorxiv_micrbio
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