calliecoombs
@calliecoombsmd
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Associate clinical professor at UC Irvine focused on CLL/SLL with side interest in CHIP/CCUS. Animal and nature lover. Tweets are my own.
San Diego, CA
Joined August 2017
RT @CllSociety: Every September 1, on World CLL Day, the global CLL community unites to raise awareness about CHRONIC LYMPHOCYTIC LEUKEMIA….
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Happy to share the long awaited manuscript on Pirtobrutinib in R/R Follicular Lymphoma - ORR 50% with mPFS of 5.8 months #MedTwitter
ashpublications.org
Key Points. Pirtobrutinib demonstrates efficacy in relapsed/refractory follicular lymphoma with an ORR of 52.1% and median DOR of 10.2 monthsPirtobrutinib
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Love it. Now, for patients needing to get imaging guided LP, what are chances radiology will listen? 🙉 #MedTwitter.
Such a useful practical study !.
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Holy smokes this will majorly change AE profiles of so many agents.
But perhaps the BIGGEST change that will affect my interpretation of trials is new neutropenia cutoffs!. v5 = Gr1 is LLN to 1500, Gr2 is 1000-1500, Gr3 is 500-1000, Gr4 is <500. Now in v6 = Gr1 is 1000-1500, Gr2 is 500-1000, Gr3 is 100-500, Gr4 is <100!!!.
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Starting as associate program director of our fellowship program and agreeing to be coordinating reviewer for ASH abstracts is making August a particularly spicy month, with so many abstracts and applications to review! But also exciting! #MedTwitter #ASH25 @UCIrvine.
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Activity looks very good but the patients on the studies don’t look quite as heavily pretreated as some other studies in this space - will be interesting to cont to follow though.
🚨 NEWS 🚨.@US_FDA grants fast track designation to birelentinib (DZD8586), a dual LYN/BTK inhibitor, for the treatment of patients with R/R CLL/SLL who have received ≥2 prior lines of therapy. Read more: #lymsm #leusm #MedNews #MedEd
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Well, this is big news! Will be important to see all the details, hopefully in an upcoming presentation
investor.lilly.com
The Investor Relations website contains information about Eli Lilly and Company's business for stockholders, potential investors, and financial analysts.
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RT @GreatDebatesCME: The real value of events like Great Debates in Hematologic Malignancies? The people. Conversations in the hallways, s….
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Looking forward to the meeting tomorrow!.
The wait is almost over. Great Debates in Hematologic Malignancies kicks off tomorrow in Los Angeles!. We’re looking forward to a weekend of dynamic debates, practical takeaways, and clinical connections you won’t find anywhere else. #Hematology #cancercare #oncology #GDHEM
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RT @GreatDebatesCME: The wait is almost over. Great Debates in Hematologic Malignancies kicks off tomorrow in Los Angeles!. We’re looking f….
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I sometimes like to think I’m a good dresser but I will never be able to top Dr. Birhiray #fASHion - great visit to Indy!
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Yikes these are sobering data - well done @BrianHill_MDPhD.
Very proud of my @ClevelandClinic mentor Dr. @BrianHill_MDPhD and former co-fellow Dr Taylor Brooks (@RoswellPark contributed) and their large study on outcomes with BSAbs in #DLBCL. Great option but more research greatly needed especially post #CART #lymsm.
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Great to see the long-term results, still remember when the study was open when I was at UNC, great work @cedittus1 and @Jmarksloan!.
Have been working w/ @Jmarksloan on this for a decade: BV-CHEP for 1L ATLL. @BrJHaem . N=16 .CR: 62.5%.ORR: 87.5%.mOS: 15.7m.AlloSCT: 5 pts; mOS: NR.Tox: cytopenias, mucositis, PN.New consideration for aggressive ATLL.
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It’s my first time attending a “Great Debates” meeting but really learning a lot from some great educators - @LymphClinician, John Leonard, Morton Coleman, and now to brush up on lower risk MDS with Dr Shastri! @GreatDebatesCME #GDHEM
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RT @ldandersonjr: FDA Eliminates REMS for Chimeric Antigen Receptor (CAR) T cell Immunotherapies. Pts now only need to remain close to CAR….
fda.gov
The REMS for currently approved BCMA- and CD19-directed autologous chimeric antigen receptor (CAR) T cell immunotherapies have been eliminated because the FDA has determined that a REMS is no longer...
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RT @RahulBanerjeeMD: 1/ Excellent news for 🇺🇸 patients receiving CAR-T therapy!. FDA has listened to data and relaxed CRS monitoring and dr….
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Oh no! This is beyond disappointing 😟.
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Wow first and maybe only time I’ll be called an influencer 😎 (majority of my views were from fan girling the LGL leukemia oral) #EHA2025.
#EHA2025 #mmsm #amlsm #leusm #cllsm #lymsm . @Eddie_Cliff @doctorpemm @Larvol @calliecoombsmd @FadiHaddad_MD @mtmdphd @sanamloghavi @tamaciro @OncoAlert
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