
jay brophy
@brophyj
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Slightly contrarian cardiologist & epidemiologist living and working in Montreal Canada
Joined January 2009
A slightly longer version (4 min read) of my take on the new revascularization guidelines as they pertain to LM disease can be found here @VictorDayan1 @kaulcsmc @drjohnm @DavidLBrownMD.
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So AC e boarding downloads still not working. They don't seem to really care. Looks like I'll need a printer to board later today. Thanks for the lack of help. @AirCanada.
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New @nejm study median 5.1 years MACE = 4.81/1000PY in #pitavastatin and 7.32/1000PY in placebo. Text claims 5 year NNT = 106. What am I missing? Looks like 5 year NNT = 1/(7.32/1000-4.81/1000) = 398 to me. Statistically significant but clinically?.
nejm.org
The risk of cardiovascular disease is increased among persons with human immunodeficiency virus (HIV) infection, so data regarding primary prevention strategies in this population are needed. In th...
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Have a short article deals with teaching, research, biases, critical reading, and foundational past research. No natural home and no interested publisher. So 1st use of Also available on my webpage
medium.com
In the winter semester we teach a small group learning course on critical appraisal for MPH students. The goal is not simply to “trash”…
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Kudos for #nejm article tackling challenging Q of extracorporeal CPR vs conventional CPR. Can Bayesian analysis provide additional insights into the published conclusion of “similar effects on survival”? One answer here @f2harrell @kaulcsmc @drjohnm
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Once again the BMJ is ahead of the curve @KamranAbbasi @fgodlee.
bmj.com
Regulatory decisions fall short of the wise stewardship required during a pandemic On 1 October 2021 Merck issued a press release1 reporting an interim analysis of Move-Out, a phase 3 randomised...
Just out @TheLancet .Failure of Molnupiravir to reduce Covid hospitalizations or deaths in a very large randomized trial (N>25,000 participants, mean age 57, 99% vaccinated)
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