BerkeLab
@berke_lab
Followers
1K
Following
86
Media
10
Statuses
43
We investigate neural mechanisms of motivation, learning, choice and action, and how these are altered in neurological & psychiatric disorders.
UCSF
Joined May 2018
The latest installment of the lab's story on DA dynamics is now published in Life. Work from @mohebial and Val Collins, in which we demonstrate how cholinergic interneurons in accumbens promote DA release and enable motivated approach.
elifesciences.org
In awake behaving rats, cholinergic interneurons in the nucleus accumbens drive dopamine release via nicotinic receptors, boosting motivation to work.
0
1
18
Checkout the latest preprint from the lab.
Folks- I have a preprint update on our #dopamine quest:."Cholinergic Interneurons Drive Motivation by Promoting Dopamine Release in the Nucleus Accumbens". I will try to summarize it here:.1/9.
0
0
5
A Spectrum of Time Horizons for Dopamine Signals.
Here's an updated version of our latest thoughts on dopamine. More data, more analyses, more words, same spirit. Will you check it out and let me know what you think?.
0
0
5
Latest preprint from our lab: Altered basal ganglia output during self-restraint .
biorxiv.org
Suppressing actions is essential for flexible behavior. Multiple neural circuits involved in behavioral inhibition converge upon a key basal ganglia output nucleus, the substantia nigra pars reticu...
0
3
11
RT @mohebial: Amin and I are delighted to host Josh @berke_lab this Thursday at 4:30pm to have a fun discussion about my favourite molecule….
0
3
0
Our new preprint is now available on biorxiv: "Striatal dopamine pulses follow a temporal discounting spectrum".
Here's a new dopamine idea we have been cooking for a while now. I think it's palatable now: Striatal dopamine pulses follow a temporal discounting spectrum. I will try to explain a few chirps, but to get the full story read our preprint. 1/n.
0
1
3
We have a position open for a staff research associate. Join our team! .
0
4
8
Join us tomorrow for the UCSF PARC international conference on pain and addiction. 8am-1:30pm PST.
0
1
4
RT @ChestekLab: Hot off the presses, #carbonfiber arrays for #electrophysiology or #dopamine sensing through #FSCV. Devices can also be pr….
0
1
0
RT @VidaConference: Hey old friends. We haven't talked for a while. ViDA is now back for an exciting one-day event in November. We are deli….
0
35
0
RT @UCSFNSGrad: As part of a new multiyear effort to increase the diversity of our faculty the Physiology Department and Neuroscience Progr….
0
13
0
0
36
0
RT @mohebial: Stop! There is a RdLight ahead. Of course, dLight is amazing, but RdLight is doubly fun. I am so happy that we got to collabo….
0
25
0
- Next-gen Cellular-scale (5x10um) silicon probes for high-density (256ch) neurophysiology with ultra-high-density packing (as little as 66µm between shanks). - Slice-in-place approach for precise registration of recording sites.
0
3
22
RT @VidaConference: Josh Berke (UCSF) @berke_lab .Dopamine firing versus dopamine release during motivated behavior. Moderator: Howard Fi….
0
6
0
RT @VidaConference: Here is our list of confirmed speakers so far. Submit an abstract by May 8th to present your own research! . You can al….
0
12
0
Preprint of a study spearheaded by Bon-Mi Gu. Here we investigated the population dynamics of rat GPe neurons during preparation-to-stop, stopping, and going. Check the full-text if you're interested!.
biorxiv.org
Flexible behavior requires restraint or cancellation of actions that are no longer appropriate. This behavioral inhibition critically relies on frontal cortex - basal ganglia circuits. A central node...
0
14
26
RT @NPP_Journal: Dopamine release drives motivation, independently from dopamine cell firing #nppjournal #hottopic from @berke_lab
https://….
0
3
0