Neuropsychopharmacology
@npp_journal
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Neuropsychopharmacology (NPP) is an official peer-reviewed publication of @ACNPorg. We report discoveries and promote training & outreach initiatives.
Nashville, TN
Joined February 2017
RT @dpn_journal: The 2025 Technology in Psychiatry Summit will take place virtually Dec 11-12! . Submissions for symposia, workshops, and p….
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RT @BlackInNeuro: We are Kicking off #BINW25 with 🔥. Join #BINSeminarSeries: Beyond the Tower ft. Dr. Tabia Pope, Sports SLP, CEO & educato….
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RT @zivacooper: Can terpenes in cannabis relieve pain? . Latest on cannabinoid-mediated analgesic effects of myrcene, a terpene found in ma….
journals.lww.com
ultitude of constituents, some of which possess analgesic potential, that have not been systematically investigated, including the terpene myrcene. Myrcene attenuates pain hypersensitivity in...
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RT @zivacooper: 🚨High-Potency Cannabis Pub🚨 .@UCLACannabis & @RANDCorporation #SystematicReview with @s_l_lake, @BeauKilmer, @conormurray p….
psychiatryonline.org
Objective: Amid continuously rising concentrations of delta-9-tetrahydrocannabinol (THC) in cannabis (i.e., potency), high-potency cannabis is a major topic in contemporary cannabis policy discussi...
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#ThisWeekInNPP. This 🔁Review🔁 highlights that early hearing loss in children, especially when combined with early life stress such as low socioeconomic status, can lead to lasting language, cognitive, & socioemotional deficits .
nature.com
Neuropsychopharmacology - Hearing and early life adversity: effects of developmental stress on sensory processing
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#ThisWeekInNPP. Unlike cocaine use alone, cocaine & alcohol polysubstance use disrupts glutamate signaling in the NAc during reinstatement of cocaine-seeking in 🐀; inhibiting prelimbic to NAc projections blocked reinstatement in cocaine-only 🐀.
nature.com
Neuropsychopharmacology - The role of the prelimbic cortex to nucleus accumbens core projection in the reinstatement of cocaine-seeking after cocaine-alcohol polysubstance use
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#ThisWeekInNPP. Compared to healthy controls, schizophrenia spectrum disorders patients showed⬆️ cell-free mitochondrial DNA levels in 🩸 & 🧠 extracellular vesicles, which correlated with ⬆️🧠 lactate levels & ⬆️ developmental stress & trauma .
nature.com
Neuropsychopharmacology - Blood and neuronal extracellular vesicle mitochondrial disruptions in schizophrenia
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#ThisWeekInNPP. Methylone (TSND-201) ⬆️ neurite branching & length in cortical neurons with effects blocked by monoamine transporter or trkB/mTOR pathway inhibitors. Methylone also⬆️ extinction recall, suggesting potential in PTSD treatment.
nature.com
Neuropsychopharmacology - Methylone promotes neurite outgrowth and has long-lasting effects on fear extinction learning
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#ThisWeekInNPP. In a🐀model of sporadic Alzheimer’s disease, chronic CBD treatment⬆️memory & social behavior, ⬇️ amyloid β and p-Tau levels, & ⬇️ neuroinflammatory markers; effects that were blocked by a CB1 receptor antagonist.
nature.com
Neuropsychopharmacology - Cannabidiol prevents cognitive and social deficits in a male rat model of Alzheimer’s disease through CB1 activation and inflammation modulation
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#ThisWeekInNPP. This✨Research Highlight ✨discusses that, despite previous hopes that CBD might buffer cannabis harms in schizophrenia, a recent RCT found no protective effect & even potential exacerbation. original article:
nature.com
Neuropsychopharmacology - For those with schizophrenia, does cannabidiol make cannabis use safer?
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#ThisWeekInNPP. This 🔥 Hot Topic 🔥 highlights wearable sleep EEG as a promising, low-burden alternative to traditional 🧠imaging for developing biomarkers in neurodevelopmental disorders, but advances in approach are needed.
nature.com
Neuropsychopharmacology - Toward scalable biomarkers: the promise of sleep wearables in neurodevelopmental research
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#ThisWeekInNPP. This 🔥 Hot Topic 🔥 emphasizes that ovarian hormone fluctuations - across the menstrual cycle, postpartum, & menopause - are key drivers of psychiatric risk in ♀️, yet remain understudied / @KundakovicLab @CognNeuroend .
nature.com
Neuropsychopharmacology - Leveraging high-resolution brain imaging and (epi)genomic approaches to improve women’s mental health
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#ThisWeekInNPP. Resting-state fMRI investigated 🧠 predictors of subjective response to methamphetamine in healthy adults. Functional connectivity patterns, especially in sensorimotor networks, reliably predicted subjective (not physiological) responses.
nature.com
Neuropsychopharmacology - Connectome-based encoding of subjective drug responses to acute oral methamphetamine
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#ThisWeekInNPP. Using a selective GPR3 agonist, the authors found significant ⬇️ in nicotine self-admin across varying doses in ♂️ & ♀️ 🐭, without affecting anxiety or general locomotion, with a focus on cholinergic neurons of the medial habenula .
nature.com
Neuropsychopharmacology - Targeting GPR3 as a novel approach for nicotine cessation therapeutic development
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What better way to kick off the week (especially after a long weekend) than with a 2-page installment of #ThisWeekInNPP 🤩 . We have the latest on nicotine, methamphetamine, CBD, polysubstance use, methylone, ovarian hormone fluctuations, & schizophrenia 👇
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This recent review article discusses how Social Determinants of Health (SDoH) shape 🧠 development & psychiatric risk (especially in early childhood) & highlights a need for targeted interventions during sensitive periods .
nature.com
Neuropsychopharmacology - Social Determinants of Health, the developing brain, and risk and resilience for psychopathology
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There are only a few hours left to submit your abstract for the annual @ACNPorg meeting ⌛️. Abstracts are due TODAY (Thurs Aug 28) by 5pm Central Time ‼️. Don't miss this opportunity to join us in the Bahamas for #ACNP2026 😎
Last chance! The deadline to submit poster abstracts is TODAY, August 28th at 5:00 pm Central. #ACNP2026
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RT @BlackInNeuro: Your neuro skills go way beyond the bench 🧠💼. Join #BlackInNeuroAltCareers at #BINW25 to hear how scientists are thriving….
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This recent study identified a role for m6A RNA methylation in MDD & suicide risk, highlighting m6A as a potential modulator of MDD pathophysiology & suicide vulnerability 🧠.
nature.com
Neuropsychopharmacology - M6A RNA epitranscriptome dynamics linked to major depressive disorder and suicide risk
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RT @dpn_journal: 🚨New Deep Dive🚨. This episode covers a recent study by Vizer et al investigating if language features extracted from smart….
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