Angela Bachi Lab
@bachi_lab
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Milan, Italy
Joined January 2020
The wait is over!! We are thrilled to announce that we have chosen Spatial Proteomics as 2024’s Method of the Year! 🥳 For more on Spatial Proteomics and a road map to this special issue, please see this month’s Editorial or read on in this thread. https://t.co/phXooJzJda
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#ESCP24 Packed lecture hall, interesting discussions with great scientific insights. This is how science should be 😊
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🎉 Excited to see our work now published @EmboMolMed Inhibition of Asparagine Synthetase Retards PKD progression. ASNS in PKD drives glutamine utilization. Work started by Christine Podrini, completed by @Sara_Cler Thanks to collaborators @FrezzaLab @bachi_lab @dalessandrolab
➡️Inhibition of #AsparagineSynthetase effectively retards #PolycysticKidneyDisease progression. By S. Clerici, C. Podrini, A. Boletta & colleagues @Boletta_Lab 🗞️ https://t.co/fiH8mG6DJE
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🚨New Study Alert!🚨 Our latest #TBT study out in @ScienceTM 💥 Acetyl-CoA carboxylase 1 controls a lipid droplet–peroxisome axis and is a vulnerability of endocrine-resistant ER+ breast cancer | Science Translational Medicine https://t.co/K0phz7ZeMJ a brief 🧵
science.org
Targeting ACC1 impairs lipid droplet– and peroxisome-dependent lipid metabolism and reverts aromatase inhibitor resistance in ER+ breast cancer.
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IFOM Women: Empowering Voices Join us for a month-long series featuring inspiring messages from the incredible IFOM women! Starting today with Silvia Marsoni until the end of February, get ready for uplifting words of wisdom & empowerment! #STEMwomen #unitednations
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Are you a student eager to dive into a dynamic research environment for your theses, master's, or PhD studies? We're excited to announce an exclusive Open Day on February 8 at our Campus! Check out e for more details: https://t.co/D9d2R5uf5c
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We are hiring!! 📢 A Predoc position is available in the lab to bridge toward Ph.D. fellowships by Oct. 2024. All at the intersection of mechanistics of self-renewal, stem cells and cancer. Links to apply below
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The Mark Foundation team spent a wonderful day of science, art, and espresso at @IFOMresearch hosted by @Albert0Bardelli - thanks for sharing your research with us! @BardelliLab @bachi_lab @FdAdF66 @LabPagani @polosimona1 @BeckyABC
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Elegant work by @KM_Havas @IFOMresearch showing how interclonal metabolic cooperation contributes to overcoming growth barriers to metastasis. Glad to have contributed with @KamradStephan @Guan06Rui @MRC_TU
science.org
Ecological interactions between tumor lineages stabilize diversity and enhance collective fitness during tumor emergence.
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How are #spatial technologies shaping our understanding of the #TME? What are the current and future challenges in the field? Find out this and more in the latest review article from the lab on the topic! https://t.co/dEBYQI5o27
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IFOM PI Dana Branzei has been awarded a prestigious Advanced Grant from the Italian Science Fund of the Ministry of University and Research, Congrats Dana and Team! ➡️ https://t.co/lrFzAxhafU
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10 amazing opportunities for PhD candidates @ IFOM through @semm_it in IFOM labs: explore them all, apply and pls circulate among your contacts! https://t.co/WQ5mGcpDHV
@BardelliLab | @bachi_lab | @LabPagani | @FdAdF66 |@yllidok | @polosimona1 | @scita_lab
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The courage of this woman scientist standing up for herself and for what's right reminds me of what Jennifer Doudna said when asked, by a female student, for career advice: "Walk into every room like you OWN THE PLACE." BRAVA! to this person and all #WomenInSTEM for doing so.
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The SEMM Call 2023 is open! many positions available at IFOM, check the call and apply!
Apply now for the innovative #PhD program in Systems Medicine: 72 positions open to work in the wide field of #biomedicine. Check out all the research lines available from #computationalbiology to #stemcells #neurobiology #structuralbiology #molecularoncology and many more
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Happy to share this publication. This was a side project for two very busy fellows, but we were lucky to have a very talented MSc student to help us. I am proud of how it turned out, thanks to @majimsa who lead all the publication process. 🧵 https://t.co/VzNJxxEAgi
onlinelibrary.wiley.com
Astrocytes react to Aβ plaques in AD, however, the precise response of astrocytes to amyloid-β (Aβ) remains uncertain. Here, we undertook a proteomic analysis of the astrocyte secretome in response...
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Glad to share this collaboration with @BeaGPerezNievas and @bachi_lab!Great work from Vittoria Matafora, Alena Gorb and Fangjia Yang, and thanks @wendyjnoble. Looking at #astrocyte secretome in response to amyloid beta👇🏻
onlinelibrary.wiley.com
Astrocytes react to Aβ plaques in AD, however, the precise response of astrocytes to amyloid-β (Aβ) remains uncertain. Here, we undertook a proteomic analysis of the astrocyte secretome in response...
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Our brand new instrument Orbitrap #Exploris240 from @thermofisher is finally flashing into new exciting metabolomics projects in @bachi_lab at @IFOMresearch! 👏🏻🎉👏🏻
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#SEMM #PROTEOMICS course -day2: today we talk of the plethora of applications for MS-proteomics, from modification profiling, to drug target reconciliation to #MALDI imaging and #structuralproteomics. Many talks (thanks to external and internal speakers) and ideas
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Ready to start the 2023 edition of the #SEMM course on #proteomics in biomedical research at #IEO #IFOM campus! Three full days of learning, exchange and discussion!
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