Aparna Nathan
@aparnanathan
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Single-cell + genetics + teaching @HarvardDBMI • writing @PopSci, @novapbs, @AAASMassMedia/@phillyhealthsci, @DrugDiscovNews and others
Boston, MA
Joined June 2015
I’m excited to share our latest work on enhancing the power to detect response expression quantitative trait loci (reQTLs) at single-cell resolution across different perturbations conditions: https://t.co/FQL0lQfvHD with @soumya_boston @broadinstitute and co-authors 👇
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Excited to share a review led by @kalaga27 describing the relationship between human autoimmunity and T cell functional traits! https://t.co/PywwMQ27k1
@broadinstitute @BrighamResearch @aparnanathan
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Very excited to share our highly collaborative work as part of the @NIH_NIAMS AMP-RA/SLE network. We mapped single cell tissue states in #rheumatoid #arthritis. https://t.co/Pqrcm1mX2u
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Hot off the press! 📢✨ Check out our in-depth review on “Methods and Insights from Single-Cell Expression Quantitative Trait Loci” 🧬📖! @AnnualReviews Had a great time writing with @Raveancic @aparnanathan @nicolesoranzo @soumya_boston
https://t.co/YRKLRa6ET4
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Single-cell genomics meets human genetics https://t.co/BHPDqhJsO5
#Review by @AnnaSECuomo, @aparnanathan, @soumya_boston, @dgmacarthur and @drjosephpowell #singlecellgenetics
nature.com
Nature Reviews Genetics - In this Review, the authors describe the emerging field of single-cell genetics, which lies at the intersection of single-cell genomics and human genetics. They review the...
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On July 1, I officially begin my position as Assistant Professor at the University of California San Diego (UCSD) in the Halıcıoğlu Data Science Institute and the Department of Medicine. I'll be recruiting grad students, postdocs, and comp techs!
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Excited to see our single-cell eQTL project finally published! It ties together everything I've worked on during my PhD, with a lot of help from @asgari_samira and @Kazu_Ishigaki
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"From building trust with readers to indulging your own curiosity, local reporters share tips for finding science stories for local audiences."
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And extra thanks to @RachelZamzow @SiriCarpenter and @beecycles for feedback (all @AAASMassMedia alums!)
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Inspired by my time at @PhillyInquirer this summer, I wrote about local science reporting for @Open_Notebook. Thanks to @sabrinaamorenoo, Mark Johnson, @MoNscience, @swadely, and @amyqin12 for sharing your wisdom
theopennotebook.com
Local media outlets often have close ties with their communities, making them unique platforms for informing and empowering readers with science stories that matter for their daily lives. This means...
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1/ Thrilled to share our work presenting the AMP ( @NIH_NIAMS @NIAIDNews) #rheumatoidarthritis single cell resource with @FanZhang_Jessie, @AHelenaJonsson1, @aparnanathan, Kevin Wei, @nghia_millard, many others. https://t.co/SkYKVUkiW9 🧵
biorxiv.org
Rheumatoid arthritis (RA) is a prototypical autoimmune disease that causes destructive tissue inflammation in joints and elsewhere. Clinical challenges in RA include the empirical selection of drugs...
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📢📢Excited to share our latest work on a genome-to-genome study of tuberculosis to search for associations between human host DNA 🧬 and the genome of the infectious agent Mtb 🦠. Here goes a 🧵 for our key findings:
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The Zhang lab @CUMedicalSchool is looking for a talented #postdoc to work on our established project using #machinelearning and #singlecell multi-omics to study immune-mediated disease! Apply at https://t.co/oXGt1zlEZa🎉 Send your CV to fanzhanglab@gmail.com if you are interested
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To hear more about my experience this summer, check out this video from @AmstatNews:
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Highly recommend applying to the AAAS MMF! I had an amazing time at @phillyhealthsci this summer—not only training as a science writer, but also getting insight into how the public engages with science
Applications are now open for the 2022 Mass Media Fellowship! If you're a STEM student or postdoc who wants to write about the top science stories next summer, consider applying before January 2nd, 2022! #scicomm Learn more and apply here:
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🥳🥳🥳 I will join @SinaiGenHealth & @SinaiGenetics as Ass. Prof. from next year. We will use statistical, population & functional genomics approaches to understand the human genetic basis of infectious diseases. AND we are hiring a postdoc, ping me if interested to chat more.
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Thrilled to share Symphony, our method for single-cell reference mapping, out now in @NatureComms 🎉: https://t.co/Ob6uqWmTe3
@ilyakorsunsky @soumya_boston
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White-tailed deer "might be picking up more than nuts and berries this year," writes @AAASMassMedia's @aparnanathan, in this reminder that zoonosis goes in both ways: https://t.co/HqUvpxNRVC
inquirer.com
White-tailed deer seemed particularly vulnerable to the virus, as they thrive in suburban and urban areas near human settlements and have similar ACE2 receptors to humans.
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My other (academic) writing project this summer: our new memory T cell eQTL study, at single-cell resolution!
Pleased to share with @aparnanathan our latest on the genetics of gene regulation in T cells, and its dynamic nature: single-cell resolution eQTL study of >500,000 resting memory T cells capturing physiologic states from 259 individuals. https://t.co/E9XTMVdHKA
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My latest for @PhillyInquirer: diving into new CDC data to figure out what we know about vaccines and variants w/@TomAvril1 @SarahGantz @AAASMassMedia @AmstatNews
inquirer.com
An important component of the CDC document was new data published Friday from a July outbreak in Massachusetts, which CDC Director Rochelle Walensky called “concerning” and “a pivotal discovery.”
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