Andy I. Nguyen
@andy_i_nguyen
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Peptide self assembly, evolution, and bioinorganic chemistry. Assistant professor at UIC
Chicago, IL
Joined February 2018
We are excited to announce our @J_A_C_S paper on frameworks with metalloprotein-like sites! ɑ-helices designed to assemble by metal-coordination and the hydrophobic effect. Point mutations yield unique frameworks with diverse metalloprotein-like sites. https://t.co/UrnPe5jOJs
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Congratulations @Ruixuan3!
The Gaoab at #UIC reports a breakthrough in volumetric fluorescence imaging, featured on the cover of Science Magazine! Their new technique, VIPS (Volumetric Imaging via Photochemical Sectioning), enables reconstruction of 3D images of whole tissues with unprecedented detail.
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BREAKING NEWS The Royal Swedish Academy of Sciences has decided to award the 2025 #NobelPrize in Chemistry to Susumu Kitagawa, Richard Robson and Omar M. Yaghi “for the development of metal–organic frameworks.”
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In @J_A_C_S, the Adibekian and Dai groups report the total synthesis of (-)-neocucurbol C, a natural product found in deep-sea fungi. It contains an unprecedented 6/6/5/5/6 polycyclic skeleton. https://t.co/lhs3a63OSx
pubs.acs.org
We report an asymmetric total synthesis of (−)-neocucurbol C, a diterpene natural product possessing a unique and complex 6/6/5/5/6 polycyclic skeleton and nine stereocenters. Pattern-recognition...
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We detail the design & synthesis of metal-ɑ-helix frameworks. If you are just interested in learning how to make #peptides, we have provided a thorough procedure for setting up your first solid phase peptide synthesis (#SPPS)! Article free until Sept 6! https://t.co/yZBOrQbEY5
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Check out our latest work on asymmetric Chan-Lam coupling, now out in JACS! https://t.co/bJCoIC7WFR
pubs.acs.org
The Chan–Lam coupling represents one of the most effective methods for constructing C–N bonds due to its mild reaction conditions and broad functional group compatibility. However, asymmetric...
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🚨 New from UIC Chemistry! Led by the Hemley group, this @ScienceMagazine study reports the first 1-dimensional high-entropy oxide nanoribbons — materials that remain stable under extreme heat (1000°C), pressure (up to 12 GPa), and corrosive environments. https://t.co/4p1gDJ2XE9
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Our first paper in the battery space is now online @ACS_AMI🔋This study was led by Simon Gersib, who discovered that a certain Mo2 paddlewheel complex has beneficial effects on the Li metal SEI. Thanks to @GlusacGroup, Matt Li, and other collaborators!! https://t.co/AHWweL498p
pubs.acs.org
The use of electrolyte additives at millimolar loadings to control the surface chemistry of lithium metal anodes (LMAs) is a leading strategy to improve lithium metal batteries and promote electros...
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Discovery of an Interlocked and Interwoven Molecular Topology in Nanocarbons via Dynamic C–C Bond Formation | Journal of the American Chemical Society @BerkeleyLab @UCBerkeley @uclachem @UCLA
pubs.acs.org
Topologically complex carbon nanostructures are an exciting but largely unexplored class of materials due to their challenging synthesis. Previous methods are low yielding because they rely on...
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New @J_A_C_S from the Adibekian Lab, marking the 3rd JACS from #UIC Chemistry this week! 🍾🍾🍾 Read it here: https://t.co/PCZkNjokNR
pubs.acs.org
Carboxylate side chains in aspartic and glutamic acids play critical roles in protein structure and function due to their polarity and negative charge. These acidic residues, which are abundant in...
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Check out our Perspective on Al(II) chemistry in @JACS_Au led by @roushanpsingh. Thanks to the editors for inviting us to participate in their special issue on sustainable small molecule activation! https://t.co/f0psSERvTM
pubs.acs.org
Promoting societally important small molecule activation processes with earth-abundant metals is foundational for a sustainable chemistry future. In this context, mapping new reaction pathways that...
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Metal-α-Helix Peptide Frameworks | Journal of the American Chemical Society @thisisUIC
pubs.acs.org
Metal–peptide frameworks (MPFs) are a growing class of metal–organic frameworks with promising applications in metalloprotein mimicry, chiral separations, and catalysis. There are limited examples of...
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🚨 New in @J_A_C_S : The @GlusacGroup at @UIC has developed a new MOF composed of nanographene ligands (hexa-peri-hexabenzocoronene), which acts as a photocatalyst for CO2 reduction using water as the terminal electron donor. Read it here! https://t.co/ZyARtrPAKd
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Pi-stacking offers powerful strategies to design structured and functional peptide materials of all dimensions. Check out our review in just out in @TrendsChemistry! https://t.co/RfBv4T0Gby
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Check out our latest with Mo-catalyzed oxidation reactions. Loving the new Flash Comm format at @Orgmet_ACS
https://t.co/fCD95rAJT6
pubs.acs.org
Whereas homogeneous molybdenum catalysis typically promotes alkene epoxidation with peroxide oxidants, here, a molybdenum bis(dithiolene) compound is shown to instead catalyze oxidative alkene...
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The Cho group at #UIC has discovered that colorectal cancers driven by APC loss depend on high membrane cholesterol to activate β-catenin signaling. Blocking cholesterol–Dvl interaction halted tumor growth without harming normal cells. @nchembio
https://t.co/OWDu348DVy
nature.com
Nature Chemical Biology - Locally elevated cholesterol in colorectal cancer cells with adenomatous polyposis coli truncation was observed to drive Wnt–β-catenin signaling through...
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Now in @NatureComms - The Hu group at UIC developed NHS-ester dye labeling to tag live mammalian cell membranes for superresolution imaging—capturing dynamic protein distribution, cell-cell contacts, nanotube formation, and intercellular transfer in vivo.
Just published: our latest on enhancing cell membrane labeling for live super-resolution imaging! Congrats to Hirushi and team! @HirushiGunasek2 @ChemistryatUIC @thisisUIC @NatureComms
https://t.co/f51t7Ii47k
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We are hiring a postdoc (or similar) with experience in molecular and cellular neurobiology and neurodegenerative disease models (cellular and animal). Appreciation for MS-based proteomics and lipidomics a must. Interested applicants can email CV to Stephanie. No DMs, please RT
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Cooperative Heterobimetallic CO2 Activation Involving a Mononuclear Aluminum(II) Intermediate | Journal of the American Chemical Society @NealMankad @ChemistryatUIC @BYU
pubs.acs.org
Molecular chemistry of aluminum most commonly involves AlIII ions due to their noble gas electronic configurations. In contrast, the chemistry of AlII ions is underexplored and may contain undiscov...
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As Chicago's only public research university, UIC knows that research matters. Over the next several weeks, UIC will highlight the impactful research happening across campus and the importance of investing in this work. We invite you to do the same using #UICResearchMatters
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